BB Lec - HISTORICAL PERSPECTIVES Flashcards
Blood was taken from 3 young men & given to the stricken
Pope Innocent VII
recommended sodium phosphate.
Braxton Hicks
Braxton Hicks recommended
sodium phosphate
discovered ABO blood groups and explained the serious reactions that occur in humans as a result of incompatible transfusions.
KARL LANDSTEINER
KARL LANDSTEINER discovered
ABO blood groups
carried out vein-vein transfusion of blood using multiple syringes & a special cannula for puncturing the vein thru the skin.
EDWARD LINDEMANN
EDWARD LINDEMANN carried out vein-vein transfusion of blood using ___ & ___ for puncturing the vein thru the skin.
multiple syringes & a special cannula
designed his syringe-valve apparatus that transfusions from donor to patient by an unassisted physician
UNGER
UNGER designed his ___that transfusions from donor to patient
syringe-valve apparatus
UNGER: designed his syringe-valve apparatus that transfusions from donor to patient by ____
an unassisted physician
reported the use of sodium citrate as an anticoagulant solution for transfusions
Hustin
Hustin reported the _______ as an anticoagulant solution for transfusions
use of sodium citrate
determined the minimum amount of citrate needed for anticoagulation and demonstrated its non toxicity in small amounts
Lewisohn
Lewisohn determined the __
minimum amount of citrate needed for anticoagulation
Rous and Turner introduced ___ for the preservation of blood
citrate-dextrose solution
when: the function of glucose in RBC metabolism is established
1930
WW II: ___ pioneered the establishment of blood banks.
Charles Drew
accomplishment of Charles Drew
establishment of blood banks
introduced the formula for the preservative acid-citrate dextrose (ACD)
Loutit and Mollison of England
accomplishment of Loutit and Mollison of England
formula for the preservative acid-citrate dextrose (ACD)
the ____ devoted nearly a dozen of papers to blood preservation
Journal of Clinical Investigation
introduced an improve preservative solution, citrate-phosphate-dextrose (CPD).
Gibson
eventually replaced ACD as the standard preservative used for blood bag
CPD
accomplishment of Gibson
citrate-phosphate-dextrose (CPD).
resolves problem in WB transfusions
COMPONENT THERAPY
AABB STANDARD: THE MAXIMUM AMOUNT OF BLOOD THAT CAN BE DONATED OR COLLECTED AT ONE TIME INCLUDING AN AMOUNT FOR SAMPLES SHALL BE
10.5 mL
A 110-lb donor can donate how many ml (maximum volume)
525 mL
A ?-lb donor can donate 525 ml
110
Total Blood Volume:
10-12 pints
Donors can replenish the fluid lost from donation of 1 pint in
24 hours.
Donor red cells are replaced w/in how many months after donation.
1-2
Donors can donate blood every ?? weeks
8
The donation process: (3 steps)
Educational reading materials.
Donor health history questionnaire
Abbreviated physical examination
Clotting was the principal obstacle in transfusion
clotting
device that requires many assistant during transfusion
Lindemanns device
was appointed director of the 1st American Red Cross Blood bank at Presbyterian Hospital.
Dr. Drew
The pilot program that he established became the model for the national volunteer blood donor program of the american red cross. Who is this person
Dr. Drew
which is less acidic? CPD or ACD
CPD
Component therapy: what are the 3 components of WB:
packed RBCs, Platelets, Plasma
became the model for the national volunteer blood donor program of the American red cross.
Pilot program of Dr. Drew
WB unit :
450 mL +/- 10%
THE MAXIMUM AMOUNT OF BLOOD THAT CAN BE DONATED OR COLLECTED AT ONE TIME INCLUDING AN AMOUNT FOR SAMPLES SHALL BE 10.5 mL. What do you call this standard
AABB Standard
