GPHT LEC - Inflammation Flashcards

1
Q

A complex reaction to various injurious agents

A

Inflammation

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2
Q

 Consists of vascular responses, migration and activation of leukocytes, and systemic reactions

A

Inflammation

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3
Q

Unique features of inflammation

A

◦ Reaction of blood vessels

◦ Accumulation of fluids and electrolytes in extravascular space

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4
Q

components of inflammatory response

A

vascular and cellular rxn

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5
Q

vascular rxn composed of

A

vasodilation

increased permeability

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6
Q

cellular rxn composed of

A
 Margination
 Rolling
 Adhesion
 Transmigration 
 Migration
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7
Q

Inflammation is terminated when

A

the inciting agent is eliminated and the mediators have degenerated.

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8
Q

A rapid response to an injurious agent that aims to rapidly bring mediators of inflammation to the site of injury

A

acute inflammation

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9
Q

characteristics of acute inflammation

A

◦ Alterations in blood flow
◦ Increased vascular permeability
◦ Emigration,accumulation,and activation of neutrophils

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10
Q

distinctive feature of acute inflammation

A

Infiltration by polymorphonuclear cells (neutrophils, eosinophils, basophils)

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11
Q

Hallmark of acute inflammation:

A

◦ Increased vascular

permeability

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12
Q

Refers to an excess fluid in the interstitial tissue or serous cavities

A

edema

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13
Q
The escape of fluid, proteins, and blood cells from the vascular system into interstitial tissue or body cavities
Two types
◦ ◦
 
Exudate Transudate
A

exudation

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14
Q

two types of exudate

high cellularity, sp gr and protein

A

exudate

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15
Q

two types of exudate

low to none cellularity, sp gr and protein

A

transudate

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16
Q

An exudate rich in inflammatory cells (leukocytes) and cellular debris

A

pus

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17
Q

morphologic patterns of acute inflammation

◦ Plasma-like effusion with no cells

A

Serous

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18
Q

morphologic patterns of acute inflammation

◦ There is abundant protein- rich fluid exudate with a relatively low cellular content

A

Serous

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19
Q

morphologic patterns of acute inflammation

◦ Early inflammation,heart failure, pleural effusions

A

Serous

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20
Q

morphologic patterns of acute inflammation
◦ Inflammation of the serous
cavities, such as peritonitis, and inflammation of a synovial joint, acute synovitis

A

Serous

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21
Q

morphologic patterns of acute inflammation

◦ Vascular dilatation may be apparent to the naked eye

A

Serous

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22
Q

morphologic patterns of acute inflammation

◦ Contains dying and degenerate neutrophils,proteins,tissue debris, infecting organisms

A

Serous

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23
Q

morphologic patterns of acute inflammation
◦ The pus may become walled-off by granulation tissue or fibrous
tissue to produce an abscess (a localized collection of pus in a tissue)

A

Serous

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24
Q

morphologic patterns of acute inflammation

◦ Caused by pyogenic bacteria

A

Serous

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25
Q

(a localized collection of pus in a tissue)

A

abscess

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26
Q

If a hollow viscus fills with pus,this is called an

A

empyema,

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27
Q

accumulation of fluid in body cavities

A

effusion

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28
Q

morphologic patterns of acute inflammation

Contains large amounts of fibrinogen

A

fibrinous

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29
Q

morphologic patterns of acute inflammation
◦ Forms thick, sticky meshwork that may cause areas to stick
together

A

fibrinous

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30
Q

morphologic patterns of acute inflammation
◦ Often seen in acute pericarditis giving the parietal and visceral
pericardium a ‘bread and butter’ appearance.

A

fibrinous

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31
Q

morphologic patterns of acute inflammation

◦ Thick fibrin coating

A

fibrinous

32
Q

morphologic patterns of acute inflammation
◦ Contains fibrinous or fibrinopurulent material with necrotic cells

A

Membranous

33
Q

morphologic patterns of acute inflammation

◦ Contains both serous and hemorrhagic materials

A

Serosanguinous

34
Q

morphologic patterns of acute inflammation

◦ Often found in mucous membranes, some microbial infection

A

Membranous

35
Q

morphologic patterns of acute inflammation

◦ Caused by bleeding, serous exudation like injury and burns

A

Serosanguinous

36
Q

Exudates in Inflammatory Processes

Contains large amount of RBCs and other cells

A

Hemorrhagic

37
Q

Exudates in Inflammatory Processes
◦ Damaged or vascular injury or permeable blood vessels or depletion of
coagulation factors

A

Hemorrhagic

38
Q

Exudates in Inflammatory Processes
◦ Acute pancreatitis due to proteolytic destruction of vascular walls, and
in meningococcal septicemia due to disseminated intravascular coagulation

A

Hemorrhagic

39
Q

Exudates in Inflammatory Processes

◦ Contains large amount of mucous and epithelial cells

A

Mucinous or Catarrhal

40
Q

Exudates in Inflammatory Processes

◦ When mucus hypersecretion accompanies acute inflammation of a mucous membrane

A

Mucinous or Catarrhal

41
Q

Exudates in Inflammatory Processes

◦ Inflammatory conditions like allergic rhinitis,common

A

Mucinous or Catarrhal

42
Q

Types of Inflammation According to Location
Localized collection of pus in a part of the body, surrounded by an inflamed area

A

abscess

43
Q

Types of Inflammation According to Location

The area will most likely look like a giant boil or cyst that can become extremely red and infected

A

abscess

44
Q

Types of Inflammation According to Location
An open sore of the skin, eyes or mucous membrane, often caused by an initial abrasion and generally maintained by an inflammation and/or an infection

A

ulcer

45
Q

Types of Inflammation According to Location
Mucosal surface
Thick mucous and white blood cells

A

catarrhal

46
Q

Types of Inflammation According to Location
Formed by the fibrin and necrotic surface epithelium

A

pseudomembranous

47
Q

Types of Inflammation According to Location

A structure which resembles the luminal surface of the tissue (looks like the affected tissue is covered by a membrane)

A

pseudomembranous

48
Q

Types of Inflammation According to Location
 An epithelium becomes coated by fibrin, desquamated epithelial cells and inflammatory cells

A

membranous

49
Q

Types of Inflammation According to Location

An example is the grey membrane seen in pharyngitis or laryngitis due to Corynebaeterium diphtheriae

A

membranous

50
Q

mononuclear cells in chronic inflammation

A

plasma cells, macrophages, lymphocytes

51
Q

slimy film covering

what morphologic pattern of acute inflam

A

membranous

52
Q

what morphologic pattern of acute inflam

in cancers, trauma, lungs

A

serosanguinous

53
Q

what morphologic pattern of acute inflam

bloody but not as viscous as blood

A

serosanguinous

54
Q

what morphologic pattern of acute inflam

diluted pink hemorrhagic material

A

serosanguinous

55
Q

mucinous exudates common in organs like

A

organs of RT and GT

56
Q

prototype of hemorrhagic exudate

A

acute pancreatitis

57
Q

common exudate, encountered by many

A

mucinous or catarrhal

58
Q

most frequent cause of abscess

A

bacteria

59
Q

what type of inflammation accdg to location/appearance

acute appendicitis

A

abscess

60
Q

what type of inflammation accdg to location/appearance

found in nose and GIT

A

catarrhal

61
Q

what type of inflammation accdg to location/appearance

found in GIT

A

pseudomembranous

62
Q

extensive deposition of collagen

A

hypertrophic scar

63
Q

CT replacement accomplished by two processes

A

angiogenesis and fibrosis

64
Q

haphazard activity of reparative cells

A

cheloid

65
Q

cells predominant in acute

A

neut

66
Q

cells predominant in chronic

A

lympho

67
Q

nucleoli in granuloma

A

horseshoe

68
Q

formation of the mature scar

A

cicatrization

69
Q

less vascular, pale, contracting tissue

A

cicatrix

69
Q

Type of inflam according to extent

Interstitial pneumonia

A

Diffuse

70
Q

Sarcoidosis type of inflammationo

A

Granulomatous inflammation

71
Q

No discernible granule type of granulomatous inflammation

A

Immune granuloma

72
Q

Type of replacement by a CT scar

Reorganization of the fibrous tissue, contraction of wound edges

A

Remodeling

73
Q

Fibrinous inflammation may lead to

A

Scarring

74
Q

Central region of abscess

A

Necrotic leukocytes and tissue cells