upper gi oral cancer

Question 1

2 types of oral cancer

Answer 1

oral cavity cancer and oropharyngeal cancer

Question 2

Oral Cavity Cancer

Answer 2

starts in mouth

Question 3

Oropharyngeal Cancer

Answer 3

Starts in oropharynx

Question 4

Head and neck squamous cell carcinoma (HNSCC)

Answer 4

Term used for cancers of the oral cavity, pharynx and larynx

Question 5

oral cancer causes (no one knows oral)

Answer 5

exact cause unknown

Question 6

oral cancer - Predisposing factors

Answer 6

▪ Constant overexposure to sun ▪ Poor oral hygiene
▪ Tobacco use
▪ Chronic ETOH use
▪ Chronic irritation
▪ Syphilis
▪ HSV
▪ HPV
▪ Immunosuppression

Question 7

Oral Cancer
Clinical Manifestations

Answer 7

Leukoplakia, Erythroplakia, 30% of pts have asymptomatic neck mass, Lip CA usually presents with indurated, painless ulcer, Tongue CA usually presents with tongue ulcer or area of thickening

Question 8

Leukoplakia (luke = white)

Answer 8

▪ White patch on mouth mucosa or tongue
▪ Precancerous lesion
▪ <15% turn into CA
▪ Patch keritonizes (becomes hard and leathery)

Question 9

Erythroplakia

Answer 9

▪ Red velvety patch on the mouth or tongue ▪ Precancerous lesion
▪ >50% progress to CA

Question 10

oral cancer - 30% of pts have

Answer 10

asymptomatic neck mass

Question 11

Lip CA usually presents with

Answer 11

indurated, painless ulcer

Question 12

Tongue CA usually presents with

Answer 12

tongue ulcer or area of thickening. ▪ Pain may occur, especially when eating hot or spicy foods
▪Later s/sx
increased salivation, slurred speech, dysphagia, toothache, earache

Question 13

Oral Cancer Diagnostic Studies

Answer 13

▪ Oral exfoliative cytologic study
▪ Scrapes suspicious lesions for microscopic examination
▪ Toluidine blue test
▪ Test for oral CA
▪ Toluidine blue is taken up by CA cells ▪ CT
▪ MRI ▪ PET