Pancreas Flashcards
pancreas releases (pancakes are TAL)
alkaline juices that neutralize acidity in stomach. trypsin - protein, lipase - fat, amalyse - carbs.
Exocrine
Exocrine: amylase, trypsin, lipase, secretin
Endocrine
Endocrine: insulin, glucagon, somatostatin
med if your pancreas doesn’t work (and give with what)
Pancrealipase (Creon). Need to take with food. Must give with COLD water.
Pancrealipase - side effects
usually due to insulin.
pancreas also releases (pancakes are bi)
Bicarbonate and water are secreted by the epithelial cells that line the pancreatic ducts-this neutralizes the acid form the stomach
acute pancreatitis
Inflammation of pancreas…micro and macrovascular failure…resulting autodigestion…SIRS…
3 stages of acute pancreatitis
Trypsin and other enzymes prematurely activate
Amylase and lipase
Intrapancreatic inflammation
Extrapancreatic/systemic injury
result of pancreatitis
Results in pancreatic pain, tissue edema, necrosis of pancreatic tissue and possibly hemorrhage
acute pancreatitis does not mean you’ll get
chronic pancreatitis
can develop what types of shock with pancreatitis?
hypovolemic, sepsis, and hemoragic.
Chronic pancreatitis (alchys get fibrous)
Chronic: progressive inflammatory disorder with destruction of the pancreas; cells are replaced by fibrous tissue; pressure within the pancreas increases, obstructing the pancreatic and common bile ducts
acute pancreatitis (just a block)
pancreatic duct becomes obstructed, and enzymes back up, causing autodigestion and inflammation of the pancreas
acute pancreatitis causes
gallstones (30%)
Alcohol (30%)
Gall bladder disease
Drugs
Hypercalcemia, hypertryglyceridemia
Infection
IBD
PUD
Trauma
Toxins
chronic pancreatitis causes
alcohol
pancreatitis - s/sx (painful pancake in my stomach and back) (these pancakes are rigid)
Pain- upper abdominal/back
Abdominal distension/ascites
Rigid abdomen, guarding
Cullen’s or Turner’s signs (bruising)
Fever
N/V
Jaundice
Hypotension
Confusion or agitation