fluid and electrolytes Flashcards
homeostasis
Volume and composition of each space remains constant. ie - disruption, vomiting, diaerrhea, ace inhibitors, diuretics
water - how much is body weight? And needed for what? (water temp eliminates and transports)
Primary component of body
Accounts for approx 60% of body wt (varies by age)
Adequate balance is necessary for- maintenance of temp - elimination of waste products - all transportation within body.
solutes - electrolytes
Chemical compounds that develop an ionic charge when dissolved in water. either + or - charge.
All body fluids contain electrolytes.
Regulation of electrolyte levels is critical for (electra on acid with muscles and bad metabolism)
maintenance of body fluid osmolality (The concentration of particles dissolved in a fluid)
acid balance
neuromuscular function
cell metabolism
nonelectrolytes - measured by what? and ex (not electra, weigh and love sugar, urea, crete, proteins)
Do not dissociate in solution
measured by wt
Glucose - Urea - Creatinine - Bilirubin - Proteins
transcellular fluids and ex.
not subject to significant gains or losses) (aceities - a fluid collects in spaces within your abdomen)
fluid spacing - 1st spacing
Normal distribution of fluid (homeostasis)
movement of body fluids
Fluid constantly moves among intracellular, interstitial and vascular spaces to maintain body fluid balance
Moves through permeable membranes
- permits movement of water and some solutes
osmosis - when is it important to consider? (intravenous is simply osmosis)
Osmosis stops when equilibrium is reached
Major force in body fluid movement
Important to consider with IV therapy
osmotic pressure (Osmosis with pebbles)
holds the water. Protein in capillary draws water into it.
Refers to pulling power of a solution for water
The higher the osmolality of a solution, greater pulling power for water
oncotic pressure (onka with colloids)
colloids (larger molecules, like protein) pull back into capillaries and plasma.
filtration (filter the straw)
Movement of fluids and solutes from an area of high hydrostatic pressure to an area of low hydrostatic pressure into or out of the capillary
Dependent on forces favoring filtration & opposing it
Think of as a tug of war - pushing and pulling
forces that work with filtration (oppposites - cap and inter)
Capillary hydrostatic pressure (blood pressure)
Interstitial oncotic pressure (water-pulling)
forces favoring reabsorption (onca reabsorbs the plasma)
Plasma oncotic pressure (water-pulling)
Interstitial hydrostatic pressure
Interstitial fluid to plasma - ex. (socks push plasma)
Fluid drawn into plasma space whenever there is increase in plasma osmotic or oncotic pressure
Wearing of compression stockings or hose is a therapeutic action on this effect
active transport
Movement of solute from an area of lower solute concentration to an area of higher solute concentration
Depends on ATP
Example is Sodium- Potassium pump
ADH
Hormone synthesized by hypothalamus
Secreted by posterior pituitary. it’s stimulated by a change in osmolarity. ie eating a lot of potato chips. ADH acts on kidneys to retain water
regulation of body fluids - so basic it’s crazy…
Thirst Mechanism
Stimulated by thirst receptors in hypothalamus
Primary protection against hyperosmolality***
Normally occurs with even small fluid losses
Stimulates release of ADH and aldosterone
causes of fluid volume excess (FVE)
Renal Disease
Too rapid infusion of IV fluids
Steroid Therapy
Production of ADH
Cardiac Disease
causes of fluid volume deficit (FVD) and what type of spacing?
NPO
Drains
Surgery
Blood loss
Fluid loss from GI tract
Profuse sweating
polyuria
fever
third spacing
decreased intake
intracellular elecrolytes (Ps indoors)
potassium and phosphorus
extracellular (plasma) electrolytes - which ones are on the outside? (outdoor pool)
sodium and chloride
most of our water in cells or plasma?
cells
Second spacing - (the 2nd you walk, you have intertitial fluid) and ex.
Abnormal accumulation of interstitial fluid. ex. - increased bp and walking a long time, then have edema in lower extremities.
third spacing (3rd base is tight) and ex.
Abnormal accumulation in areas that have no or little amt of fluid
Fluid unavailable for use ex. ascities. body has the fluid but it’s trapped in other areas, not for circulation.
hypotonic (cell is opposite of vj)
cell is swollen - more solute to water inside cell than water surrounding it. at risk for cerebral edema