Pharm HIV antivirals Flashcards
covid and masks are not
allowing ppl to build immunities
rsv
is flu for infants - they breathe so their nose - need to know how to suction
herp 2
2 ovaries
chickenpox called
vzv
cyotmegalovirus
often seen in HIV - causes blindness
herpes zoster test is the
pcr test
acylovir
1 drug for chickenpox, herpes 1 and 2
canciclovir
CMV retinitis - can cause blindness in HIV. can do occular implants w/ meds. Can cause bone toxicity - low RBC, low platelets, what CBC count carefully.
oseltamirvir (tamaflu)
start within 2 days. causes N/V - to be expected.
zanamivir (Relenza)
for flu
ribavirin
need to wear PPE (check this), it’s teratogenic - also can cause it in men. Also used to treat for Hep C.
Hep C
leading cause of liver failure and transplant
A patient with a perioral infection with herpes simplex virus (HSV-1) can expect the antiviral medication to cure the lesions, but drug therapy cannot cure genital herpes
False
An82-year-oldwomanisunabletotakethe influenzavaccinedue to allergies, but she has been exposed to the virus through a family reunion. Shedoes not yet have symptoms of the flu. Which option would be best for her?
She should begin oral oseltamivir therapy as soon as possible.
adherence
antiretroviral
assembly
budding
CD+ T cells
CCR5 antagonists
CD+ T cells
highlyactive antiretroviral therapy
(HAART)
entry inhibitors
immune response
Reverse transcriptase (RT)
Long Term Survival= 10-15 years
finish these terms
HIV - Transmitted by
sexual activity, intravenous drug use, perinatally from mother to child
Time between infection & enough antibodies for a positive HIV test
Duration: approximately 6 wks to 3 months
Primary Goal HIV
viral load < 50 Copies/mL- considered undetectable
Seroconversion - (check this term)
Point at which HIV test becomes positive
Time period between seroconversion and onset of HIV/AIDS-related illness
Duration variable: < 1 year to > 15 years
Time period between seroconversion and onset of HIV/AIDS-related illness
Duration variable: < 1 year to > 15 years
HIV to AIDS
The CD4 count is above 500 cells/mL - HIV.
CD4 below 200 (AIDS) =ProphyaltIc Treatment AIDS
Anti-retroviral Drugs
Monitor for signs of opportunistic diseases
Highly Active Antiretroviral Therapy (HAART)
Highly Active Antiretroviral Therapy (HAART) is
the current treatment recommendation. combo of all antretroviruses.
HAART goals
Decreased viral load to undetectable levels (<50
Copies/mL)
Improved CD4+ T cell count (>500/mm3)
HIV numbers
500 – 1600: normal
200 – 500: Beginning of HIV illness
< 200: AIDS
Nucleoside/Nucleotide
side - Sugar tide - Train
zidovudine (Retrovir®) A Z T
mother loves baby from A to Z.
Sustiva® (Efavirenz, Stocrin) - s/s
suicidal thoughts
Entry Inhibitors -Fusion Inhibitor
* Fuzeon®
fuzzy coat - your inhibiting from getting into the cell
sub q
always assess the site
Raltegravir (Isentress®)
cola colored urine
HIV
TB is the main one
usually take antivirals
in the am
lactic acid test
for sepsis?
