cardiac peds Flashcards
group A hemolytic strep (GAS) connected to what disease?
connected to rheumatic fever
Rheumatic Fever (RF)- Definition - think rheumatic
- Inflammatory connective tissue disease following -
Group A B-hemolytic streptococcal pharyngitis (GAS) infection - Potentially serious consequences to the heart * Affects: joints, brain, skin tissues
Rheumatic Fever - patho (just antibodies)
Autoimmune response
– Body generates antibodies – to destroy bacteria
– Structural similarity between the bacterial cell wall and heart valve tissue
– Results in damage to the valves from the body’s own immune system
know difference between
rheumatic fever and rheumatic heart disease
Rheumatic Fever - FACTS
Favored by poor living conditions & overcrowding
* Lack of health care * Lack of knowledge
Rheumatic Fever Etiology - when do hallmark signs appear?
(Rhemy is my fav number)
- Major or hallmark signs may occur 1-3 weeks
- After untreated or partially treated group A beta-hemolytic streptococcal infection
5 Major Clinical Manifestations (rheumatic fever is a SPECC on the door)
- Carditis
- Polyarthritis
- Erythema marginatum
- Subcutaneous nodules
- Chorea
Rheumatic Fever - which test for the criteria? (it’s a name)
jones - on test
Rheumatic Fever affects what part of the heart?
heart valves
1st Major Manifestation: Carditis
Inflammation of the heart
* Types:
* Pericarditis: inflammation of the pericardium
* Myocarditis: inflammation of myocardium-heart muscle
* Endocarditis: inflammation of the endocardium
Carditis - symptoms - what kind of heart sounds?
- Chest pain
- Fatigue
- Fever
- Tachycardia
- Pericardial friction rub
- CHF – signs and symptoms
- Cardiomegaly
- Chest x-ray
- Echocardiogram
- Activity restrictions
Carditis - does it cause permanent damage?
Progressive valve damage in time * Involvement of mitral or aortic
* ONLY manifestation
to cause permanent damage
Polyarthritis - RF
Polyarthritis: 2 or More Large Joints
Polyarthritis - what locations in the body?
- Wrists
- Hips
- Elbows
- Shoulders * Knees
- Ankles
- Pain
- Swelling – (edema) * Tenderness
- Heat
- Erythema - Red
- Inflammation
know mitral
aortic valves
5th Major Manifestation: Chorea - RF
(corey is a spaz)
St Vitus Dance
or Sydenham chorea (SD)
* Involuntary, purposeless, jerking movements of arms, legs, and face
* Facial grimacing
* Speech disturbances
* Emotional changes
5th Major Manifestation: Chorea - does it go away? after how long?
(Korea is only 5)
Increased by anxiety & attempts at fine motor
* Will eventually disappear – Can last 5-15 weeks
Antistreptolysis (ALSO) (ASOT)
Antistreptolysis-O (ASLO) titers
measures the concentration of antibodies formed in the blood against Streptolysin-O
* Titers rise 7 days after onset reach maximum levels 4-6 weeks
* (2) rising ASLO evidence recent strep infection
Clinical Management for RF - what meds?
- Penicillin – acute & long term (Intramuscular benzathine Penicillin G)
- Or erythromycin
- Aspirin – fever, arthritis, & arthralgia’s
- Corticosteroids - if significant Carditis
People who have RF or RHD - does it reoccur?
- At risks for recurrent episodes
- Following streptococcal throat infection * IF –they do not receive regular penicillin * Injections or oral
ALSO is
(also the titer)
the titer
Kawasaki Disease (KD) - is there a fever?
- Acute febrile, systemic vascular inflammatory disorder
- Leading cause of acquired heart disease
- Generalized vasculitis of unknown etiology
Who’s at Risk? Kawasaki Disease (KD)
50% occur in children under 2 years old * 80% are younger than 5 Years-old
* Higher incidence in
– Asian and Pacific Island origin
use aspirin instead of tylenol
because of the platelets
Kawasaki Disease (KD) - is it person to person?
- Etiology unknown
- Not spread person-person
- Geographic & seasonal outbreaks * Late winter and early spring
- Pediatric illness which suggests (?) passive immunity
Etiology and Pathophysiology - Kawasaki Disease (KD) - what part of the heart is affected?
- Infectious or possibly toxic trigger initiates immune response
- Multisystem inflammatory disease
- Affects small, midsize, & coronary arteries * Can cause aneurysms
Pathophysiology - kawaski
- Infiltration causes edema and inflammation
- Weakened vascular walls
- Leading to aneurysms
- Fibrous connective tissue forms
- Thickening and scarring the vascular walls