CenB: ZSO15A Transportmechanisme III (blad 4) Flashcards

1
Q

HCO3- concentratie in de cel

A

15 mM

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2
Q

HCO3- concentratie buiten de cel

A

24 mM

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3
Q

Ca2+ concentratie in de cel

A

10^-7 M

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4
Q

Ca2+ concentratie buiten de cel

A

10^-3 M

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5
Q

Functies van de Na-K-pomp

A
  • Concentratiegradiënt voor Na+ en K+ genereren.
  • Binnen negatieve Vm genereren.
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6
Q

concentratie Na+ in del

A

15 mM

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7
Q

concentratie Na+ buiten de cel

A

145 mM

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8
Q

concentratie K+ in de cel

A

120 mM

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9
Q

concentratie K+ buiten de cel

A

4,5 mM

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10
Q

Gevolg remming van de Na-K-pomp door ouabaïne

A

ICF Na+ stijgt, ICF K+ daalt

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11
Q

Hoezo zorgt de Na-K-pomp voor een negatieve Vm in de cel

A

Het is een elektrogene pomp, er is een netto uitgaande stroom van +1

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12
Q

Hoe is de elektrochemische gradiënt van calcium gericht

A

Naar binnen:
- membraanspanning naar binnen
- chemische gradiënt naar binnen

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