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aa Orgo > Pharm Final 3 > Flashcards

Pharm Final 3 Flashcards

1
Q 
Clinical use of Sympathomimetics
a
a
a
c
o
a
n
A 
asthma 
anaphylactic shock 
ADHD (not Epi, but other related drugs)
Cardiac arrest 
Ocular surgery 
Adjunct with local anesthesia
nasal decongestant
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2
Q

Not epi, but related drugs are used for ADHD. They stimulate areas in the brain to retain focus. They’re related to

A

amphetamines

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3
Q

Epi is good for eye surgery b/c (1) it dilates the pupil and (2) it constricts the eye __ to reduce blood loss

A

artery

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4
Q

Sympathomimetics can be used as nasal decongestant by

A

decreasing blood flow that had accumulated from inflammation

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5
Q

examples of sympathomemitics used as nasal decongestants are

A

pseudoephedrine and ephedrine (which are used to make crystal meth)

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6
Q

Toxic effects of sympathomemitics

A

tachycardia, arrhythmias, CV hemorrhage hypertension

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7
Q

phenylephrine is which class of drug

A

sympathomimetic

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8
Q

unlike epinephrine which is nonspecific, phenylephrine is _ specific

A

alpha specific

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9
Q

phenylephrine, agonist or antagonist?

A

agonist

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10
Q

all alpha specific sympathomimetic drugs do what to blood vessels

A

constrict

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11
Q

phenylephrine does what to blood vessels

A

constricts

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12
Q

is used to treat cold/allergy symptoms (like nasal congestion)

A

phenylephrine

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13
Q

2 contraindications for phenylephrine

A

hypertension and narrow angle glaucoma

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14
Q

phenylephrine interaction with MAO inhibitors causes

A

hypertension

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15
Q

phenylephrine interaction with TCA causes increased ___ effect

A

sympathomimetic effect

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16
Q

Example of a sympathomimetic Beta agonist

A

Albuterol

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17
Q

albuterol side effects include tremor, dizzy, nervous, excited, insomnia, and

A

tachycardia

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18
Q

Albuterol is contraindicated in CV disorder, __ and __

A

diabetes and hyperthyroidism

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19
Q

phenylephrine has drug interactions with __ inhibitors and __

A

MAO inhibitors and TCA

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20
Q

example of sympathetic alpha blockers

A

Prazosin

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21
Q

sympathetic alpha blockers (Prazosin) effect on BP

A

decrease

22
Q

used to treat BP in pheochromocytoma

A

sympathetic alpha blockers (Prazosin)

23
Q

benign tumor of the adrenal gland resulting in increase secretion of NE and EPI

A

pheochromocytoma

24
Q

Used to reverse the vasoconstrictive effects of DA and NE

A

sympathetic alpha blockers (Prazosin)

25
Q

Used for benign prostatic hyperplasia

A

sympathetic alpha blockers (Prazosin)

26
Q

side effects include orthostatic hypotension, miosis (constricting pupil), tachycardia, nasal congestion, confusion, headache, dry mouth, cant ejaculate

A

sympathetic alpha blockers (Prazosin)

27
Q

the tachycardia side effect of sympathetic alpha blockers (Prazosin) is in response to the dropping

A

BP

28
Q

Do not take sympathetic alpha blockers (Prazosin) with ___ drugs because you will get hypertension and tachycardia

A

sympathomimetic

29
Q

Example of a sympathetic beta blocker

A

Propranolol

30
Q

the suffix “olol” means its what class of drug

A

sympathetic beta blocker

31
Q

Propranolol causes decrease in renin released from kidneys. This causes BP to

A

decrease

32
Q

parasympathetic system has _ receptors

A

m receptors

33
Q

_ receptor is found in the skeletal muscle and ganglion

A

N receptor

34
Q

Sweat glands are activated by the SNS, but instead of NE, __ is involved (even though it’s the SNS)

A

ACH

35
Q

drug that you need to withdraw slowly to avoid tremors and headaches

A

propranolol

36
Q

class of drug derived from fungus

A

Ergot alkaloids

37
Q

ergot alkaloid prototype

A

ergotamine

38
Q

Ergot amine interacts with DA and ___ receptors

A

adrenergic

39
Q

ergotamine pregnancy category

A

X

40
Q

used for treatment of acute migraine

A

ergotamine

41
Q

ergotamine treats migraines by preventing ____

A

vasodilation

42
Q

parasympathomimetic drugs, you have direct acting and indirect acting. Indirect acting drug work by inhibiting

A

acetycholinesterase

43
Q

Prototype, sympathomimetic non specific

A

epinephrine

44
Q

Prototype, sympathomimetic a-adrenergic agonist

A

phenylephrine

45
Q

Prototype, sympathomimetic b-agonist

A

albuterol

46
Q

Prototype, sympathetic a blocker

A

prazosin

47
Q

Prototype, sympathetic b blocker

A

propranolol

48
Q

Prototype, cholinergic/parasympathomimetic, direct acting

A

bethanechol

49
Q

Prototype, cholinergic/parasympathomimetic, indirect acting, crosses BBB

A

Tacrine

50
Q

Prototype, cholinergic/parasympathomimetic, indirect acting, does not cross BBB

A

pyridostigmine

51
Q

Prototype, parasympathomimetic blockers (3 of them)

A

atropine
Ipratropium bromide
oxybutyrin

aa Orgo (196 decks)

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