Pharm Final 3

Question 1

Clinical use of Sympathomimetics
a
a
a
c
o
a
n

Answer 1

asthma 
anaphylactic shock 
ADHD (not Epi, but other related drugs)
Cardiac arrest 
Ocular surgery 
Adjunct with local anesthesia
nasal decongestant

Question 2

Not epi, but related drugs are used for ADHD. They stimulate areas in the brain to retain focus. They’re related to

Answer 2

amphetamines

Question 3

Epi is good for eye surgery b/c (1) it dilates the pupil and (2) it constricts the eye __ to reduce blood loss

Answer 3

artery

Question 4

Sympathomimetics can be used as nasal decongestant by

Answer 4

decreasing blood flow that had accumulated from inflammation

Question 5

examples of sympathomemitics used as nasal decongestants are

Answer 5

pseudoephedrine and ephedrine (which are used to make crystal meth)

Question 6

Toxic effects of sympathomemitics

Answer 6

tachycardia, arrhythmias, CV hemorrhage hypertension

Question 7

phenylephrine is which class of drug

Answer 7

sympathomimetic

Question 8

unlike epinephrine which is nonspecific, phenylephrine is _ specific

Answer 8

alpha specific

Question 9

phenylephrine, agonist or antagonist?

Answer 9

agonist

Question 10

all alpha specific sympathomimetic drugs do what to blood vessels

Answer 10

constrict

Question 11

phenylephrine does what to blood vessels

Answer 11

constricts

Question 12

is used to treat cold/allergy symptoms (like nasal congestion)

Answer 12

phenylephrine

Question 13

2 contraindications for phenylephrine

Answer 13

hypertension and narrow angle glaucoma

Question 14

phenylephrine interaction with MAO inhibitors causes

Answer 14

hypertension

Question 15

phenylephrine interaction with TCA causes increased ___ effect

Answer 15

sympathomimetic effect

Question 16

Example of a sympathomimetic Beta agonist

Answer 16

Albuterol

Question 17

albuterol side effects include tremor, dizzy, nervous, excited, insomnia, and

Answer 17

tachycardia

Question 18

Albuterol is contraindicated in CV disorder, __ and __

Answer 18

diabetes and hyperthyroidism

Question 19

phenylephrine has drug interactions with __ inhibitors and __

Answer 19

MAO inhibitors and TCA

Question 20

example of sympathetic alpha blockers

Answer 20

Prazosin

Question 21

sympathetic alpha blockers (Prazosin) effect on BP

Answer 21

decrease

Question 22

used to treat BP in pheochromocytoma

Answer 22

sympathetic alpha blockers (Prazosin)

Question 23

benign tumor of the adrenal gland resulting in increase secretion of NE and EPI

Answer 23

pheochromocytoma

Question 24

Used to reverse the vasoconstrictive effects of DA and NE

Answer 24

sympathetic alpha blockers (Prazosin)

Question 25

Used for benign prostatic hyperplasia

Answer 25

sympathetic alpha blockers (Prazosin)

Question 26

side effects include orthostatic hypotension, miosis (constricting pupil), tachycardia, nasal congestion, confusion, headache, dry mouth, cant ejaculate

Answer 26

sympathetic alpha blockers (Prazosin)

Question 27

the tachycardia side effect of sympathetic alpha blockers (Prazosin) is in response to the dropping

Answer 27

BP

Question 28

Do not take sympathetic alpha blockers (Prazosin) with ___ drugs because you will get hypertension and tachycardia

Answer 28

sympathomimetic

Question 29

Example of a sympathetic beta blocker

Answer 29

Propranolol

Question 30

the suffix "olol" means its what class of drug

Answer 30

sympathetic beta blocker

Question 31

Propranolol causes decrease in renin released from kidneys. This causes BP to

Answer 31

decrease

Question 32

parasympathetic system has _ receptors

Answer 32

m receptors

Question 33

_ receptor is found in the skeletal muscle and ganglion

Answer 33

N receptor

Question 34

Sweat glands are activated by the SNS, but instead of NE, __ is involved (even though it's the SNS)

Answer 34

ACH

Question 35

drug that you need to withdraw slowly to avoid tremors and headaches

Answer 35

propranolol

Question 36

class of drug derived from fungus

Answer 36

Ergot alkaloids

Question 37

ergot alkaloid prototype

Answer 37

ergotamine

Question 38

Ergot amine interacts with DA and ___ receptors

Answer 38

adrenergic

Question 39

ergotamine pregnancy category

Answer 39

X

Question 40

used for treatment of acute migraine

Answer 40

ergotamine

Question 41

ergotamine treats migraines by preventing ____

Answer 41

vasodilation

Question 42

parasympathomimetic drugs, you have direct acting and indirect acting. Indirect acting drug work by inhibiting

Answer 42

acetycholinesterase

Question 43

Prototype, sympathomimetic non specific

Answer 43

epinephrine

Question 44

Prototype, sympathomimetic a-adrenergic agonist

Answer 44

phenylephrine

Question 45

Prototype, sympathomimetic b-agonist

Answer 45

albuterol

Question 46

Prototype, sympathetic a blocker

Answer 46

prazosin

Question 47

Prototype, sympathetic b blocker

Answer 47

propranolol

Question 48

Prototype, cholinergic/parasympathomimetic, direct acting

Answer 48

bethanechol

Question 49

Prototype, cholinergic/parasympathomimetic, indirect acting, crosses BBB

Answer 49

Tacrine

Question 50

Prototype, cholinergic/parasympathomimetic, indirect acting, does not cross BBB

Answer 50

pyridostigmine

Question 51

Prototype, parasympathomimetic blockers (3 of them)

Answer 51

atropine Ipratropium bromide oxybutyrin