4092 6 cancer Flashcards

1
Q

teletherapy

A

a type of radiation therapy that uses an external beam

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2
Q

brachytherapy

A

Internal radiation therapy

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3
Q

3 Routes of administration of chemotherapy administration

A

IV, regional, oral

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4
Q

Myelosuppression

A

Bone marrow suppression; which means there’s less RBCs, WBCs, and platelets

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5
Q

Stomatitis

A

swelling/sores of the mouth (its a side effect of cancer treatment)

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6
Q

Neoplasm

A

a new and abnormal growth of tissue in some part of the body, especially as a characteristic of cancer.

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7
Q

Tumor

A

a swelling of a part of the body, generally without inflammation, caused by an abnormal growth of tissue, whether benign or malignant

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8
Q

4 Stages of Carcinogenesis

A

Initiation
Promotion
Malignant conversion
Progression

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9
Q

Cell Cycle Replication

A
G0 phase
G1 phase
S phase
G2 phase
M phase
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10
Q

3 Benign tissue examples

A

Fibromas
Lipomas
Leiomyomas

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11
Q

3 Malignant tissue examples

A

Carcinoma in situ
Malignant fibrosarcomas
Bronchogenic carcinomas

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12
Q

promote cell proliferation and are capable of triggering cancerous characteristics

A

Oncogenes

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13
Q

the expression of oncogenes may be caused by the decrease in the body’s immune surveillance (caused by ___, ___)

A

stress, carcinogens

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14
Q

Central to the theories of cancer: damaged ___

A

DNA

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15
Q

Central to the theories of cancer: Impairment of the

A

immune system

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16
Q

Cellular Mutation: Initiation: Permanent

A

Permanent damage in the cellular DNA as a result to exposure to a carcinogen (radiation, chemicals)

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17
Q

Cellular Mutation: Promotion: May

A

May last for years, includes conditions such as smoking or alcohol use that act repeatedly on the already affected cells

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18
Q

Cellular Mutation: Progression: Inherited

A

Inherited changes acquired during the cell replication develop into a cancer

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19
Q

CA Risk Factors: p____

A

poverty

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20
Q

Carcinogens: hormones like

A

estrogen and testosterone

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21
Q

Carcinogens: End products of metabolism, (eg. ___ ___)

A

Bile acids

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22
Q

Yearly mammograms are recommended starting at age

23
Q

Cervical Cancer: Screening should begin approximately

A

three years after a women begins having vaginal intercourse, but no later than 21 years of age

24
Q

Cervical Cancer: Screening should be done every year with Pap tests or

A

every two years using liquid-based tests

25
Cervical Cancer: At or after age 30, women who have had three normal test results in a row may get screened
every 2-3 years
26
Cervical Cancer: Women 70 and older who have had three or more consecutive Pap tests in the last ten years may
choose to stop cervical cancer screening
27
Cervical Cancer: Screening after a total hysterectomy (with removal of the cervix) is not necessary unless
the surgery was done as a treatment for cervical cancer
28
Colon Cancer: starting at 50 you can do one of these 5 choices
- FOBT, yearly - sigmoidoscopy, 5 years - FOBT plus sigmoidoscopy, 5 years - double-contrast barium enema, 5 years - colonoscopy, 10 years
29
Prostate Cancer: The prostate-specific antigen (PSA) test and the digital rectal examination (DRE) should be offered annually, beginning at age
50
30
Primary prevention:
limiting exposure to carcinogens and increasing protective factors
31
Secondary prevention:
Identifying high risk groups, screening them
32
a measure of cancer occurrence in terms of cancer incidence and mortalilty
Absolute risk
33
an estimate of increased probability of developing a certain cancer based on amount of exposure to the associated risk factors. The higher the relative risk, the greater the risk of developing that specific cancer
Relative risk
34
the arithmetic difference in cancer rates between the group exposed to the factor and the unexposed group factor
Attributable risk
35
Benign tumors do not
metastasize
36
highly differentiated tumor
Benign
37
slow growing tumor
Benign
38
poorly differentiated tumor
Malignant
39
tumor that is Cohesive
Benign
40
tumor that has Well-defined borders
Benign
41
tumor that Pushes other tissues out of the way
Benign
42
tumor that Does not recur
Benign
43
tumor that Does not stop at tissue border
Malignant
44
tumor that Invades and destroys surrounding tissues
Malignant
45
tumor that Metastasizes to distant sites
Malignant
46
Malignant Cells have simplified
metabolic activity (work is more simple that normal cells)
47
``` C A U T I O N ```
``` Change in bowel habits A sore that won't heal Unusual bleeding Thickening of a lump Indigestion Obvious change is a mole Nagging cough/hoarseness ```
48
Dx testing: hormones you might look for
HCG | Calcitonin
49
Dx testing: Oncofetal antiagens you might look for
CEA | AFP
50
Dx testing: Specific proteins you might look for
PSA Immunoglobulin (monoclonal) CA 125 CA-19-9
51
the treatment of choice for most types of cancer
chemo
52
Chemotherapy may be use as adjuvant treatment with
surgery and radiation
53
destroys cancer cells with minimal exposure of normal cells to the damaging effects
Radiation therapy
54
effective on tissues directly within the path of the beam
Radiation therapy