HESI Cardiovascular system Part 2 Flashcards

1
Q

Within the intercalated discs, adjacent cells are connected by ___ and ____ ___

A

desmosomes

gap junctions

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2
Q

action potentials in the heart come form specialized cardiac muscle cells called ______ cells

A

autorhythmic cells

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3
Q

The autorhythmic cells are concentrated in 2 areas, the ___ __ and the ___ ___

A

sinoatrial node

atrioventricular node

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4
Q

The sinoatrial node is located in the

A

right atrium

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5
Q

The atrioventricular node gets its action potential from the

A

sinoatrial node

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6
Q

The cardiac cycle is initiated by the

A

sinoatrial node

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7
Q

The atrioventricular node sends action potential to the

A

atrioventricular bundle (bundle of His)

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8
Q

The ventricles are stimulated by impulses from the ___ ___

A

atrioventricular bundle

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9
Q

the ___ ___ conduct the action potential from the inter ventricular septum down to the apex and back up through the ventricles

A

purkinje fibers

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10
Q

the first step in cardiac muscle contraction, depolarization occurs when channels open to allow ___ to enter

A

Na+

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11
Q

the second step in cardiac muscle contraction, ___ enters the cytosol from the sarcoplasmic reticulum and also form outside the cell

A

Ca2+

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12
Q

Within the cell, Ca2+ binds to

A

troponin

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13
Q

Once Ca2+ binds to troponin, this stimulates ___-___ binding which leads to the sliding of actin filaments past myosin filaments

A

cross-bridge

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14
Q

repolarization occurs as ___ channels opens and ___ diffuses out of the cell

A

K and K

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15
Q

Compared to skeletal muscle, the refractory period of cardiac muscle is

A

longer, ensuring each contraction is followed by enough time to allow the heart chamber to refill with blood before the next contraction

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16
Q

In an ECG, the ___ wave is small, representing the depolarization of the atria.

A

P

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17
Q

During this wave, muscles of the atria are contracting

A

P

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18
Q

ECG, a rapid down-up-down movement

A

QRS

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19
Q

Represents the depolarization of the ventricles

A

QRS

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20
Q

represents the repolarization of the ventricles

A

T

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21
Q

A contraction event (of either atria or ventricles) is called

A

systole

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22
Q

a relaxation event is referred to as

A

diastole

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23
Q

The ___ ventricular relaxation is the period during which the ventricles are released and the AV and semilunar valves are still closed. The volume of the ventricles remains unchanged

A

isovolumetric ventricular relaxation

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24
Q

Ventricular filling begins as the AV valves open and blood fills the ventricles. The ventricles remain in ___ during this time

A

diastole

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25
Blood fills the ventricles in 3 phases. First it flows in quick since there's plenty of space. Second it flows slower since there's less room. Third, atrial systole forces the last of the blood in. The final amount of blood at this point is called the ___ ___
end-diastolic volume
26
Ventricular contraction (systole) starts as the action potential form the ___ node enters the ventricle.
AV node
27
___ contraction occurs when the AV valves are forced shut. During this brief period, while semilunar valves are still closed, the volume of the ventricles remains unchanged
isovolumetric contraction
28
The amount of blood remaining in the ventricles after relaxing is the ___ ___
end-systolic volume
29
___ ___ is the volume of blood ejected by each ventricle during a single contraction
stroke volume
30
___ ___ is the number of heartbeats per minute
heart rate
31
___ ___ is the volume of blood pumped out of the right or left ventricle per minute
Cardiac output
32
If you're in really good shape, your cardiac output while exercising could be 7 times your cardiac output during resting! The ratio between the maximum and resting cardiac output is called the ___ ___
cardiac reserve
33
a factor of stroke volume is ___, which is the degree to which cardiac cells are stretched by blood entering the chambers
preload
34
a factor of stroke volume is ___, the degree to which cardiac cells contract as a result of extrinsic influences
contractility
35
a factor of stroke volume is ___ which is a measure of the pressure that must be generated by the ventricles to force the semilunar valves open
afterload
36
The greater the after load, the smaller the stroke volume. ___ (which is narrowing of blood arteries) and high blood pressure increase after load and reduce stroke volume
arteriosclerosis
37
The ___ nervous system may influence heart rate
autonomic
38
blood vessels have 3 layers, tunica ___, tunica ___, tunica ___
tunica intima tunica media tunica adventitia
39
The inner layer facing the blood
tunica intima
40
tunica media is made of ___ ___
smooth muscle
41
tunica adventitia is made of ___ tissue
connective tissue
42
3 kinds of arteries
Elastic, muscular, arterioles
43
The biggest kind of artery
elastic artery
44
capillaries are microscopic with very thin walls, they only have 1 layer which is the tunica ___
intima
45
type of capillary, the blood vessels between arterioles and venules.
metarterioles (precapillaries)
46
metarterioles (precapillaries) are not true capillaries because they have __ __
smooth muscle
47
type of capillary, makes up the bulk of the capillary bed
true capillary
48
true capillaries don't have muscle in their walls, but they do have a ring of smooth muscle (fact)
nothing
49
three kinds of true capillaries
Continuous Fenestrated Sinusoidal
50
most common true capillary
continuous capillary
51
true capillary with pores (fenestrations)
fenestrated capillary
52
type of capillary used in the kidney because it is especially porous
fenestrated capillary
53
true capillary that has large gaps that allow blood cells to pass through. Found in the bone marrow, spleen, liver
sinusoidal capillary
54
3 kinds of veins
postcapillary venule venules veins
55
type of vein thats very porous with scattered smooth muscle
postcapillary venule
56
In veins, the tunica intima and tunica media are ___ compared to arteries
thinner
57
One thing veins have that arteries dont
valves (to prevent back flow)
58
Many regions of the body receive blood supplies from 2 or more arteries. The points where these arteries merge are called arterial ___
arterial anastomoses
59
the pressure measured during contraction of the ventricles
systolic pressure
60
systolic pressure average ___ mm Hg in arteries of the systemic circulation
110
61
the pressure measured during ventricular relaxation
diastolic pressure
62
diastolic pressure averages ___ mm Hg
75
63
Blood pressure is basically ___ mm Hg in the veins
0
64
Because there's no blood pressure in the veins, 2 pumps move the blood
muscular pump | respiratory pump
65
veinous pump, arises from contractions in skeletal muscle surrounding veins (squeezes them and the blood has no where else to go because of the valves)
muscular pump
66
veinous pump, moves blood by pressure changing during inhalation
respiratory pump
67
the part of the brain that regulates blood pressure
medulla oblongata
68
The cardiovascular center receives information about the state of the body from 3 sources
Baroreceptors Chemoreceptors Higher brain regions
69
sensory neurons that monitor arterial blood pressure
Baroreceptors
70
sensory neurons that monitor levels of CO2 and O2
chemoreceptors
71
The ___ provide a hormonal mechanism for the regulation of BP by managing blood volume
kidneys
72
In response to rising blood pressure, cells in kidneys secrete ___ into the blood
renin
73
___ and ___, hormones secreted by the adrenal medulla, raise blood pressure by increasing heart rate and the contractility of the heart muscles. These hormones are secreted as part of fight-or-flight response
epinephrine and norepinephrine
74
___ hormone, a hormone made by the hypothalamus and released by the posterior pituitary, raises blood pressure by stimulating the kidneys to retain water
Antidiuretic hormone
75
___ ___ ___, a hormone secreted by the atria of the heart, lowers blood pressure by causing vasodilation and by stimulating the kidneys to excrete more water and Na+
Atrial natriuretic peptide