VASCULITIS CLINICAL

Question 1

based on histo exam and P-ANCA

with non specific systemic reactions:
fever, weight loss
renal failure
hypertension
abdominal pain

Answer 1

polyarteritis nodosa

Question 2

C-ANCA in 95% of patients

Answer 2

wegener’s granulomatosis

Question 3

palpable purpura
P-ANCA in 70% of cases
hemoptysis, hematuria, and proteinuria
bowel pain and bleeding
muscle pain and weakness

Answer 3

microscopic polyarteritis

Question 4

age > 50; F:M
50% of cases develop in background of polymyalgia rheumatica
diplopia to transient or complete vision loss
nonspecific symptoms: fever, fatigue, wt loss, facial pain, headache

Answer 4

giant cell arteritis

Question 5

females < 40 y/o

symptoms: vascular insufficiency, leg claudication, pulmonary hypertension, cor pulmonale

Answer 5

takayasu’s arteritis

Question 6

fever
bilateral non-purulent conjunctivitis
erythema of palms and soles with edema processing to desquamation
rash of red plaques or pustules
lymphodenopathy
cardiac manifestations: arrhythmia, dilation, CHF, MI

Answer 6

kawasaki’s disease

Question 7

prominent painful lesions of extremities, remitting, relapsing inflammation

thromboses of medium sized arteries and veins of extremities

young adult smokers

Answer 7

thromboangiitis obliterans (Buerger’s disease)

Question 8

pallor, cyanosis
young, healthy women
no morphologic changes

Answer 8

raynauds disease/phenom