CNS INJURY HIGH YIELD I

Question 1

neurons are organized how in the CNS?

Answer 1

topographically organized into nuclei, ganglia, and columns

Question 2

marked H/E staining in hypoxic injuries

Answer 2

cell body shrinks
pyknosis of nucleus
nucleolus disappears
nissl is lost
eosinophilia
axonal swelling
disruption of axonal transport

Question 3

neural injury patterns

Answer 3

evident acute injury
coagulative necrosis
apoptosis
chromatolysis

Question 4

main patterns of neuronal injury

Answer 4

acute hypoxic ischemic injury
axonal spheroids
axonal injury, swelling of the body

Question 5

astrocytes are responsible for what?

Answer 5

repair and scar formation

Question 6

gliosis is the most important indicator of CNS injury that involves?

Answer 6

shrinkage of astrocytic cytoplasm

tightly interwoven cellular processes

Rosenthal fibers

Question 7

oligodendrocytes used for? found?

Answer 7

production and maintenance of CNS myelin

most common in white matter

Question 8

ependymal cells used for?

Answer 8

lining of ventricular walls in brain and central canal of spine
-targeted in infectious agents (CMV)

Question 9

microglial cells is used as what in the CNS?

Answer 9

phagocytosis in the CNS derived from bone marrow

Question 10

what are the features unique to the brain?

Answer 10

brain fxn localized in NS

Brain protects and more vulnerable to insult

similar symptoms produced through different pathological mech

certain diseases are unique in neuropathology