TRANSFUSION COMPLICATIONS Flashcards
1
Q
name the reaction from this cause and mech:
ABO mismatch
Ab-Ag activation, complement cascade, intravascular hemolysis
A
acute hemolytic reaction
2
Q
name the reaction from this cause and mech:
Rh mismatch; IgGs form previous pregnancy/transfusion
extravascular hemolysis (no complement activation)
A
delayed hemolytic reaction
3
Q
name the reaction from this cause and mech:
HLA mismatch; WBC Ags
Ab-Ag release of endogenous pyrogens from WBCs
A
febrile nonhemolytic reaction
4
Q
name the reaction from this cause and mech:
IgA mismatch in IgA deficient patients
Ab-Ag reaction involving IgE
A
anaphylactic reaction
5
Q
name the reaction from this cause and mech:
plasma protein mismatch (other than IgA)
Ab-Ag reaction involving IgE; mast cell degranulation
A
allergic (urticarial) reaction
