GROWTH FACTORS Flashcards
1
Q
what are the GFs involved in ECM deposition and scar formation?
A
TGF-B
platelet derived growth factor
cytokines
2
Q
name this growth factor?
stimulates production of collage, fibronectin, proteoglycans and inhibits collagen degradation
- decreases proteinase activity
- increases activity of TIMPS (tissue inhibitors of metalloproteinases)
A
TGF-B
3
Q
name this growth factor?
causes migration and proliferation of fibroblasts and smooth muscle cells
A
platelet derived growth factor (PDGF)