HEMOSTASIS INTRO Flashcards
process involved in formation of fibrin clots
Coagulation
result of well-regulated processes which maintains blood in a fluid state in normal
Hemostasis
hemostasis involves?
vascular wall w/ lining endothelium
platelets
coagulation proteins
primary hemostasis involves?
*steps
platelets and blood vessels
*brief period of vasoconstriction
platelet adhesion
platelet change shape
platelets release granule causing more recruitment
platelet aggregates and form a hemostatic plug
secondary hemostasis involves?
*steps
coagulation proteins
*endothelial cells release tissue factor
tissue factor causes platelets to express phospholipid complex
phospholipid complex activates thrombin
thrombin causes fibrin polymerization
controlled bleeding, counter regulatory mech set into motion