TEST I HIGH YIELD Flashcards

1
Q

cellular response to injury is based on?

A

type
duration
severity

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2
Q

consequences of cell injury depends on?

A

type
state
adaptibility

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3
Q

vulnerability of systems based on?

A

cell membrane
aerobic respiraton
protein synthesis
genetic apparatus

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4
Q

mechanisms of cell injury?

A
ATP depletion
mitochondrial damage
influx of calcium
accumulation of oxygen
defects in membrane permeability 
damage to DNA
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5
Q

ROS is produced by?

A

endogenous redox reactions
phagocytic production
nitric oxide

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6
Q

what are the intracellular accumulations?

A

abnormal metabolism
protein mutation
lack of enzyme
ingestion of indigestible materials

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7
Q

necrosis is based on?

A

ischemia
free radicals
nuclear damage
types of necrosis

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8
Q

2 pathways that activate caspases?

A

mitochondrial pathway

death receptor pathway

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9
Q

what are the signs of swelling?

A

rubor
tumor
dolar
calor

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10
Q

definitions of inflammation?

A

edema
exudate
purulent exudate
transudate

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11
Q

steps to getting WBCs outside blood vessel?

A

margination/rolling
adherence
transmigration
chemotaxis

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12
Q

outcomes of acute inflammation?

A

resolution
abscess
scar formation
chronic inflammation

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13
Q

main products of arachidonic acid metabolites?

A

cyclooxygenases
lipoxygenases
platelet activating factor
cytokines

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14
Q

cytokines involved in acute inflammation?

A

TNF
IL-1
IL-6
chemokines

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15
Q

cytokines involved in chronic inflammation?

A

IL-12
IFN-gamma
IL-17

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16
Q

plasma proteases comprises of?

A

complement
kinin
clotting systems

17
Q

characteristics of chronic inflammation?

A

tissue destruction
repair
infiltration

18
Q

causes of chronic inflammation?

A

persistent infections
prolonged exposure to toxic agents
autoimmunity

19
Q

what are the of chronic inflammation?

A
monocyte
lymphocytes
mast cells
eosinophils
neutrophils
20
Q

morphologic patterns in acute and chronic inflammation?

A

serous inflammation
fibrinous inflammation
suppurative inflammation
ulcer