NEOPLASIA BASICS TERMS

Question 1

neoplasia equals?

Answer 1

new growth

Question 2

Abnormal mass of tissue whose growth exceeds and is uncoordinated with that of
the normal tissues

Answer 2

Neoplasm

Question 3

made up of transformed

neoplastic cells

Answer 3

Parenchyma

Question 4

connective tissue, blood

vessels, and lymphatics

Answer 4

Supporting stroma

Question 5

– It will remain localized

– Amenable to local surgical removal

Answer 5

Benign Neoplasms

Question 6

Implies that the lesion can invade and destroy adjacent structures and spread to
distant sites (metastasize) to cause death

Answer 6

Malignant Neoplasms

Question 7

arising from epithelial tissue

Answer 7

Carcinoma

Question 8

arising from mesenchymal tissue

Answer 8

Sarcoma

Question 9

arising from the lymphoreticular

system

Answer 9

Lymphoma

Question 10

arising from hematopoietic

elements

Answer 10

Leukemia

Question 11

– A mass of disorganized tissue indigenous to the particular site, such as the lung or the liver
– Considered a developmental malformation, it has chromosomal aberrations and is considered neoplastic

Answer 11

Hamartoma

Question 12

– A congenital anomaly consisting of a heterotopic nest of cells. For example, a small nodule of well-developed and normally organized pancreatic tissue may be found in the submucosa of the stomach, duodenum, or small
intestine.

Answer 12

Choristoma

Question 13

the extent to which
parenchymal cells of the neoplasm resemble
comparable normal cells, both
morphologically and functionally

Answer 13

Differentiation

Question 14

lack of differentiation

Answer 14

Anaplasia

Question 15

Disorderly growth

Encountered principally in epithelial lesions

Dysplasias do not necessarily progress to
cancer but are precursors

Answer 15

Dysplasia

Question 16

replacement of one type of cell with another type; nearly always found in association with tissue damage, repair, and regeneration

Answer 16

metaplasia

Question 17

benign epithelial neoplasm derived from glands, although they may or may not form glandular structures

Answer 17

adenoma

Question 18

benign epithelial neoplasms producing microscopically or macroscopically visible finger like or warty projections from epithelial surfaces

Answer 18

papillomas

Question 19

macroscopically visible projection above a mucosal surface and projects, for example, into the gastric or colonic lumen

Answer 19

polyp

Question 20

testicular tumor

Answer 20

seminoma

Question 21

benign, focal malformation that resembles a neoplasm in the tissue of its origin

Answer 21

hamartoma