INHIBITORS OF COAGULATION TERMS

Question 1

anticoagulant serine protease that inactivates thrombin & factors IXa, Xa, XIa,XIIa

Answer 1

Antithrombin III

Question 2

anticoagulant serine protease that inactivates factors VIa and VIIIa

Answer 2

Protein C

Question 3

a Vitamin-K-dependent cofactor for protein C

Answer 3

Protein S

Question 4

results in venous thrombosis (procoagulant), hereditary or acquired

autosomal dominant is what type of antithrombin III deficiency

caused by pregnancy, oral contraceptives, liver disease,
extensive malignancy, DVT, DIC, major surgery is what type of antithrombin III deficiency

Answer 4

Antithrombin III Deficiency

Hereditary ATIII Deficiency

Acquired ATIII Deficiency

Question 5

results in increased risk of thrombosis(prothrombotic)

Answer 5

Protein C Deficiency

Question 6

results in increased risk of thrombosis

Answer 6

Protein S Deficiency

Question 7

breaks down/ attacks fibrin clot (splits it into various fragments) and reduces fibrin polymerization

Answer 7

Plasminogen-Plasmin

Question 8

▪ Streptokinase, urokinase
▪ t-PA (tissue plasminogen activator)
▪ Factor XIIa
▪ Kallikrein
▪ HMW kininogen

these are the substances of?

Answer 8

plasminogen plasmin sys

*Substances capable of converting plasminogen to plasmin: