ABNORMAL WBC MORPHOLOGY Flashcards

1
Q

types of abnormal WBC morphology?

A

Auer rods
toxic granulation
dohle inclusion bodies
hypersegmentation

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2
Q

linear or spindle shaped red-purple inclusions in blasts or promyelocytes

derivatives of azurophilic granules

usually seen in pathologic conditions (AML)

A

Auer rods

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3
Q

dark blue to purple cytoplasmic granules, peroxidase positive

found in severe infections or other toxic conditions

A

toxic granulation

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4
Q

small oval inclusions in the peripheral cytoplasm of neutrophils which stain pale blue with wrights stain

remnants of free ribosomes or rough ER

frequently accompanies toxic granulation

A

dohle inclusion bodies

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5
Q

normal neutrophils have 2-5 lobes connected by a thin chromosome strand

hypersegmentation occurs if:
>5% of neutrophils have 5 lobes or more

1% of neutrophils have 6 lobes or more

seen in?

A

hypersegmentation

megaloblastic anemia, B12 deficiency

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