ANTITUMOR EFFECTOR MECHANISM

Question 1

this is the dominant anti tumor mechanism in vivo

Answer 1

cell mediated immunity

Question 2

specially sensitized cytotoxic T cells

virus associated neoplasms

Answer 2

cytotoxic t lymphocytes

Question 3

lymphocytes capable of destroying tumor cells without prior sensitization

1st line of defense against tumor cells

lyse tumors with IL-2 and IL-15

Answer 3

natural killer cells

Question 4

activated macrophages exhibit selective cytotoxicity against tumor cells in vitro

secretion of reactive metabolites

TNF-alpha lytic for several types of tumor cells

Answer 4

macrophages

Question 5

although there is no evidence for the protective effects of anti humor antibodies against spontaneous tumors, administration of monoclonal antibodies against tumor cells can be therapeutically effective

Answer 5

humoral mechanism

Question 6

what are the two mechanisms involved in the humoral response?

Answer 6

activation of complement system

induction of ADCC by NK cells