LAB TESTS

Question 1

normal is 150,000 – 400,000 /mm3

Answer 1

Platelet Count

Question 2

normal is >100,000/mm3

Answer 2

Bleeding Time

Question 3

tests ability of platelet rich plasma to aggregate in presence of ADP, collagen, epinephrine, thrombin, and ristocetin (which is associated w/ vWD)

Answer 3

Platelet Aggregation Studies

Question 4

(PT) time it takes for plasma to form a fibrin clot following the addition of complete tissue thromboplastin and Ca2+

Answer 4

Prothrombin Time

Question 5

(aPTT/PTT) time it takes for plasma to form a fibrin clot
following the addition of Ca2+
,phospholipid reagent, and contact activators (ground glass)

Answer 5

Activated Partial Thromboplastin Time

Question 6

(TT) times it takes for plasma to form a fibrin clot following the addition ofthrombin

Answer 6

Thrombin Time

Question 7

A point-of-care coagulation test (bedside, intraoperative)

Answer 7

Activated Clotting Time (ACT)

Question 8

Designed to measure plasma heparin (unfractionated heparin (UH) and low molecular weight
heparin (LMWH))

Answer 8

Anti-Xa Assay (Heparin Assay)

Question 9

can be assayed both functionally and immunologically

Reduced in both:
▪ Acquired coagulopathies – DIC, liver dysfunction, fibrinolytic states

▪ Hereditary coagulopathies – afibrinogenemia, dysfibrinogenemia, hypofibrinogenemia

Answer 9

Fibrinogen Levels

Question 10

fibrinogen levels reduced in both?

Answer 10

acquired coagulopathies
-DIC, liver dysfunction, fibrinolytic states

hereditary coagulopathies
-afibrinogenemia, dysfibrinogenemia, hypofibrinogenemia

Question 11

If inhibition of Factor X

Answer 11

aPTT & PT are prolonged, normal TT time

Question 12

If inhibition of Factor IX

Answer 12

aPTT prolonged, and PT is normal

Question 13

Decreased fibrinogen

Answer 13

all tests prolonged