CELLULAR RESPONSES TO INJURY Flashcards
what is the nature of injurious stimulus?
altered physiological stimuli; some nonlethal injurious stimuli
reduced oxygen supply; chemical injury, microbial infection
metabolic alterations, genetic or acquired; chronic injury
cumulative sublethal injury over long lifespan
what are the cellular responses? and also for apoptosis
cellular adaptations
cell injury
intracellular accumulation; calcification
cellular aging
for this injurious stimulus, what is the effect?
altered physiological stimuli; some nonlethal injurious stimuli
increased demand and stimulation
decreased nutrients and stimulation
chronic irritation
for this injurious stimulus, what is the effect?
reduced oxygen supply; chemical injury, microbial infection
acute and transient
progressive and severe including DNA damage
for cellular response, what is the effect?
cellular adaptations
hyperplasia
atrophy
metaplasia
for cellular response, what is the effect?
cell injury
acute reversible injury, cellular swelling fatty change
irreversible injury to cell death
necrosis