CNS TUMORS Flashcards

1
Q

what are the CNS TUMORS?

A

astrocytoma
-diffuse
-pilocytic
meningiomas

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2
Q

about 80% of adult primary brain tumors

mutation in p53 and Rb genes and gain of function in p13k pathways

seizures, headache, focal neurologic deficits

Grading
Low grade astrocytoma
Anaplastic Astrocytoma
Glioblastoma Multiforme

what is this astrocytoma, a CNS TUMOR?

A

Diffuse Astrocytoma

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3
Q

what is this astrocytoma, a CNS TUMOR??

a tumor in kids and teens/young adults

Found in cerebellum – cystic lesions w/ mural nodules, and Rosenthal fibers

Usually benign; (behaves in a benign fashion in the majority of cases)

A

Pilocytic Astrocytoma

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4
Q

usually benign (slow-growing) adult tumor

Attached to the dura – arise from meningothelial cells of arachnoid

Compress the underlying brain

Among the varied histologic patterns are

syncytial
fibroblastic
transitional
psammomatous
secretory

what tumor is this?

A

Meningiomas

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5
Q

this tumor is diffuse or pilocytic?

A

astrocytoma

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6
Q

where is diffuse astrocytoma found?

A

cerebral hemispheres

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7
Q

major cause of diffuse astrocytoma?

A

p53 and Rb genes

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8
Q

grading of diffuse astrocytoma is based on?

A

degree of differentiation

low grade astrocytoma
anapestic astrocytoma
glioblastoma multiforme

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9
Q

where are pilocytic astrocytoma found?

benign or malignant

A

cerebellum

benign

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10
Q

meningiomas are benign or malignant?

A

benign

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11
Q

major histologic pattens of meningiomas?

A
syncytial
fibroblastic 
transitional
psammomatous
secretory
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