TYPE II ANTIBODY MEDIATED Flashcards

1
Q

what are the antigens?

A

normal molecules intrinsic to cell membrane or ECM

absorbed exogenous antigens

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2
Q

what are the mechanisms of antibody mediated response and disease?

A

opsonization and phagocytosis

inflammation

antibody mediated cellular dysfunction

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3
Q

what are the two types of antibody mediated cellular dysfunction?

A

graves disease

myasthenia gravic

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4
Q

TSH receptor
antibody mediated stimulation of TSH receptors
hyperthyroidism

A

graves disease

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5
Q

acetylcholine receptor
antibody inhibits acetylcholine binding, down modulates receptors
muscle weakness, paralysis

A

myasthenia gravis

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