TYPE II ANTIBODY MEDIATED Flashcards
1
Q
what are the antigens?
A
normal molecules intrinsic to cell membrane or ECM
absorbed exogenous antigens
2
Q
what are the mechanisms of antibody mediated response and disease?
A
opsonization and phagocytosis
inflammation
antibody mediated cellular dysfunction
3
Q
what are the two types of antibody mediated cellular dysfunction?
A
graves disease
myasthenia gravic
4
Q
TSH receptor
antibody mediated stimulation of TSH receptors
hyperthyroidism
A
graves disease
5
Q
acetylcholine receptor
antibody inhibits acetylcholine binding, down modulates receptors
muscle weakness, paralysis
A
myasthenia gravis