INFLAMMATION II HIGH YIELD

Question 1

what are the cells of chronic inflammation?

Answer 1

monocyte
lymphocyte
mast cells
eosinophils
neutrophils

Question 2

what are the predominant cell types of granulomatous inflammation?

Answer 2

activated macrophage with epitheloid appearance, multinucleate giant cells

Question 3

what are the two types of granulomatous inflammation?

Answer 3

foreign body granulomous

immune granulomous

Question 4

what are the morphologic patterns in acute and chronic inflammation?

Answer 4

serous inflammation
fibrinous inflammation
suppurative/purulent inflammation

Question 5

what is an example of suppurative/purulent inflammation?

Answer 5

abscess

Question 6

ulcers are commonly encountered in?

Answer 6

mucosa of mouth, stomach, intestines of genitourinary tract

skin and subcutaneous tissue of lower extremities in older people with circulatory disturbances

Question 7

what are the systemic effects of inflammation?

Answer 7

fever
leukocytes
elevated plasma levels of acute phase reactants

Question 8

chemical mediators of inflammation?

Answer 8

from plasma or produced locally

usually use receptors

amplification of response

short lived

may act on only one target cell or on a few target cells

potential for harmful effects

Question 9

what terminates the acute inflammatory response?

Answer 9

short half lives of chemical mediators

inflammation triggers

• leukotrienes to lipoxins
• liberates TGFB
• neural impulses inhibits production of TNF in macrophages

Question 10

what are the anti-inflammatory mechanisms?

Answer 10

lipoxins
complement reg proteins
IL-10
TGFB