Poultry Top Topics - Top 20 Poultry Diseases Part 1 Flashcards
what is the other name for newcastle disease?
avian pneumoencephalitis
what is the classic case presentation of newcastle disease?
acute onset of severe respiratory and/or neurologic and/or gi signs
what respiratory signs are seen in newcastle disease?
gasping, sneezing, coughing, facial edema causing square head, & reddened lower eyelid over the lymphoid patch
what neuro signs are seen in newcastle disease?
paralysis, tremors, droopy wings, torticollis, circling, but bright & alert despite severe neuro deficits
what gi signs are seen in newcastle disease?
watery green diarrhea
what other clinical signs apart from respiratory, neuro, & gi may be seen in chickens with newcastle disease?
sometimes sudden death
decreased egg production with thin shells & watery albumin
what is the etiology of newcastle disease?
RNA avian paramyxovirus-1
what is the gold standard test for dead & alive birds with newcastle disease?
dead birds - virus isolation on lung, kidneys, or gi tract
live birds - virus isolation from nasopharyngeal & tracheal exudate swabs
what lesions seen on necropsy are almost pathognomonic for newcastle disease?
multifocal necrosis, hemorrhagic intestinal mucosa especially at lymphoid foci (cecal tonsils)
how is ICPI used in chickens?
for newcastle disease - day old chicks are inoculated to determine virulence of newcastle
how will a newcastle disease positive chicken test on hemagglutination?
positive
how is RT-PCR used on newcastle chickens?
done for pathotyping & genotyping
how is newcastle disease treated?
no treatment - have to cull all birds on the premises
how is newcastle disease prevented?
good management practices as the disease spreads quickly through facilities through aerosol exposure
indoor operations are better - outdoor flocks are at a higher risk
vaccines in countries where virulent virus disease outbreaks occur
T/F: outdoor flocks are at a larger risk of getting newcastle than indoor flocks
true
how are the different types of avian paramyxovirus labeled based on ICPI?
how fast they kill embryos post-inoculation
lentogenic - slow, used in vaccines & not reportable
mesogenic - medium
velogenic - fast & divided into 2 categories: viscerotropic (gi) velogenic newcastle disease & neurotropic (brain) velogenic newcastle disease
how do different strains of APV1/PMV-1 vary?
differences in surface glycoproteins, hemagglutinin-neurominidase (HN), & fusion (F)
what strains of newcastle disease are reportable in the united states?
mesogenic & velogenic strains
what is the zoonotic risk of newcastle disease?
causes transitory conjunctivitis in humans
what is the classic case presentation of marek’s disease?
clinical signs based on which organs/tissues t-lymphocytes infiltrate
sciatic nerve paralysis - one foot forward & one back
gray eye - lymphocytic infiltration of iris
affects young chickens 2-5 months old - decreased growth rate, egg production, & enlarged feather follicles which are a cause of condemnation
what is the etiology of marek’s disease?
oncogenic lymphotrophic alphaherpesvirus genus mardivirus
how is marek’s disease diagnosed?
virus isolation, PCR (for viral dna in lymphoid tumors), AGID
histopath & IHC
what found on necropsy helps to distinguish marek’s disease from lymphoid leukosis?
the bursa is rarely affected & is usually atrophic in marek’s
where are lymphoid tumors from marek’s disease found in the body? what else is seen at necropsy?
liver, spleen, gonads, heart, lungs, kidney, muscles, & proventriculus
enlarged peripheral nerves - especially sciatic nerve
how is marek’s disease treated?
none - supportive care in pet poultry
what prophylactic treatment is done to prevent marek’s disease?
vaccinate in ovo or day old chicks to decrease shedding