Feline Flash Notes - Injection Site Sarcoma Flashcards
what is the common signalment of cat affected by an injection sit sarcoma?
adult cat 7-9 years old with an enlarging skin mass
what are injection site sarcomas associated with?
inactivated, killed vaccines - adjuvant (rabies & FeLV)
other injections with multiple injections given at one site
what is the biological behavior of injection site sarcomas?
locally aggressive, invasive, high recurrence, & low metastasis
what is the test of choice for diagnosing an injection site sarcoma?
INCISIONAL biopsy & consultation with a board certified oncologist & surgeon
what is the treatment of choice for injection site sarcomas?
aggressive surgical excision with complete margins
radiation therapy to treat microscopic disease
T/F: the first treatment of injection site sarcomas have the best chance of successful outcome
true
what does the prognosis of injection site sarcomas depend on?
depends on the stage, location, ability to resect the tumor with margins, & if mets are present
how are injection site sarcomas prevented?
vaccinate at locations that allow for aggressive surgical removal (distal limbs)
use non-adjuvanted products
avoid multidose vials & polyvalent vaccines
a 7 year old cat presents with a 5 month history of an enlarging, non-painful mass between her shoulders. the cat has been vaccinated annually with FVRCP, rabies, & FeLV. the cat isn’t showing any signs of overt illness. physical exam, cbc, chem, & UA are all normal. injection site sarcoma is suspected.
what is the most appropriate test to support the presumed diagnosis?
incisional biopsy & consult with board certified oncologist & surgeon
what is the treatment of choice for injection site sarcoma?
aggressive surgical excision with complete margins & radiation therapy for microscopic disease
what are 4 things that can be done to prevent/decrease the chances of injection site sarcomas?
vaccinate at the distal limbs
avoid multidose vials
avoid polyvalent vaccines/products
use non-adjuvanted vaccines
what are two risk factors for development of injection site sarcomas?
- inactivated killed vaccines with adjuvants - rabies/FeLV
- multiple injections given in one location
