Canine Top 20 Diseases - Part 1 Flashcards
what is the classic case presentation of diabetes mellitus?
PU/PD/PP + weight loss
what is the classic case presentation of a very ill or DKA patient?
vomiting, inappetence, & lethargy
what is the classic case presentation of hyperadrenocorticism?
PU/PD/PP/PANTING
pot bellied appearance, truncal alopecia, cutaneous thinning, & calcinosis cutis
what is the classic case presentation of collapsing trachea?
toy/small breed middle aged dog with a honking cough that is elicited with increased activity or exercise that ends with the animal retching
what is the classic case presentation of IMHA?
patient is icteric, lethargy, weak, increased pallor, variable degrees of organomegaly, & discolored urine from hemoglobinuria or bilirubinuria
what is the classic case presentation of IVDD?
PAIN!!! in the neck or back, arched back or head down, ataxia, paraparesis, tetraparesis, or paraplegia
what is the classic case presentation of a severe case of collapsing trachea?
cyanosis & exercise intolerance
how is diabetes mellitus diagnosed?
chemistry panel - hyperglycemia
fructosamine - elevated levels indicate BG levels over 2 weeks
urinalysis - glucosuria, elevated USG, +/- ketonuria
how is hyperadrenocorticism diagnosed? include expected findings on CBC, chemistry, UA, urine cortisol:creatinine, ACTH stim test, LDDST, endogenous ACTH, HDDST, & abdominal ultrasonography.
CBC - stress leukogram (neutrophilia, lymphopenia, eosinopenia) + thrombocytosis
chemistry - elevated ALP & hypercholesterolemia
UA - hyposthenuria +/- proteinuria
urine cortisol:creatinine: if normal, rules out cushings, if abnormal, further testing indicated
ACTH stim: test of choice for iatrogenic cushings (excessive cortisol response)
LDDST: more sensitive for PDH/ADH (no suppression, or loss of suppression at 8 hours)
endogenous ACTH: used to differentiate between PDH & ADH (if low, PDH, if normal to high, ADH)
HDDST: in PDH 75% will suppress & 25% will not but in ADH, there will be no suppression
abdominal ultrasound: in PDH, same size of adrenals or bilateral enlargement, in ADH: one adrenal gland is enlarged & the other is small or not seen
how is collapsing trachea diagnosed?
rads - may be hard to see dynamic collapse
fluoroscopy - I would think this is best
endoscopy - requires general anesthesia
how is IMHA diagnosed? include expected findings on CBC, saline agglutination test, coomb’s test, etc.
CBC - anemia, +/- reticulocytosis, spherocytes, polychromasia, & anisocytosis, icteric serum on PCV
positive saline agglutination test
positive coomb’s test for antibodies against RBC
infectious disease testing - 4DX test!!!
how is IVDD diagnosed?
MRI - safe, fast, & best quality
CT - safe & faster than MRI but lower quality
myelogram - invasive & seizures may occur during recovery
how is a stable diabetes mellitus patient treated?
long acting insulin (NPH or vetsulin)
increased fiber in the diet & RX diabetic diet
how is an ill/DKA patient treated?
hospitalization with supportive care, regular insulin CRI until controlled, & potassium/phosphorus derangements are corrected
what test can be done to rule out stress hyperglycemia when trying to diagnose diabetes mellitus?
fructosamine