A&P - Chapter 27 (Part 6) Flashcards

1
Q

What is the largest WBC?

A

Monocytes

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2
Q

What are 2 characteristics of monocytes?

A
  1. Mobile
  2. Highly phagocytic
    - aggressive (engulf larger pathogens and cancerous cells)
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3
Q

Macrophages

A

Are specialized monocytes that grow to several times their original size after they migrate out of the blood
- large eaters

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4
Q

What kind of tissues are RBCs and WBCs produced by? (2)

A
  1. Myeloid tissue
    - red bone marrow
  2. Lymphatic tissue
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5
Q

Hematopoeisis

A

RBC and WBC formation

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6
Q

What are hematopoietic stem cells?

A

Precursors of RBCs, WBCs and platelets

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7
Q

Where is myeloid tissue mainly found? (3)

A

In adults…

  1. Sternum
  2. Ribs
  3. Hip bones
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8
Q

What do myeloid tissues form?

A

All types of blood cells

- although most lymphocytes and monocytes develop in lymphatic tissue

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9
Q

Where are lymphatic tissue found? (3)

A
  1. Lymph nodes
  2. Thymus
  3. Spleen
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10
Q

What do lymphatic tissues form? (2)

A
  1. Lymphocytes

2. Monocytes

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11
Q

Thrombocytes

A

Blood clotting cells

- Platelets

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12
Q

What is the shape of platelets?

A

Small, irregular spindles or oval disks

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13
Q

What are 3 important properties of platelets?

A
  1. Agglutination
  2. Adhesiveness
  3. Aggregration
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14
Q

What essential role do platelets play?

A

Blood clotting roles

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15
Q

How do platelets work? (6)

A
  1. Injury to a blood vessel
    - rough/damaged lining
  2. Clotting factors are released at the injury site produce prothrombin activator
  3. Platelets become sticky and accumulate at the injury site
    - soft temporary platelet plug
  4. Prothrombin activator and calcium convert prothrombin into thrombin
  5. Thrombin reacts with fibrinogen and changing it to fibrin
  6. Fibrin then traps RBCs to form a clot
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16
Q

Prothrombin

A

A protein normally present in the blood

17
Q

Thrombin

A

A protein important to blood clotting

18
Q

Fibrinogen

A

A soluble blood protein

19
Q

What does fibrin look like?

A

Tangle of threads

20
Q

What does fibrin do?

A

Traps RBC to form a clot

21
Q

What is an example of coagulation?

A

Vitamin K

22
Q

What does vitamin K do?

A

Stimulates liver cells to increase synthesis of prothrombin

23
Q

What does it mean if you have a faster production of thrombin?

A

Faster formation of clots

24
Q

What can clots do?

A

Shut off blood supply to vital organs

25
Q

What can clots lead to? (2)

A
  1. Strokes

2. Heart attack

26
Q

Thrombus

A

A stationary blood clot

- stays where it is formed

27
Q

Thrombosis

A

Condition of having a thrombus

28
Q

Embolus

A

Term used for a part of a thrombus which dislodges and circulates through the bloodstream
- may block a blood vessel

29
Q

Embolism

A

Condition of having an embolus

30
Q

What is hemophilia characterized by?

A

An inability to form blood clots

31
Q

What is hemophilia related to?

A

X-linked inherited disorders

- x recessive

32
Q

Who do x-linked traits effect?

A

Males

33
Q

Hemophilia

A

Failure to produce one or more of the plasma proteins involved in blood clotting

34
Q

What happens if hemophilia is left untreated?

A

It can be life threatening