A&P - Chapter 27 (Part 2) Flashcards
What is dependant on hemoglobin? (2)
- Transport
2. Exchange of O2 and CO2 between blood and cells
What does Hb transport ? (2)
- O2 and oxyhemoglobin
2. CO2 as carbaminohemoglobin
How many globulin chains are there in Hb?
4
What do the globulin chains attach onto?
The heme groups
Anemia
Inability of the blood to carry adequate oxygen to body cells
When can anemia occur? (2)
- Deficiency of RBCs
- Deficiency of Hb
- even if there are adequate numbers of RBCs
What are 6 types of anemia?
- Aplastic anemia
- Pernicious anemia
- Folate deficiency anemia
- Blood loss or hemorrhagic anemia
- Iron deficiency anemia
- Sickle cell anemia
What types of anemia is related to the number of RBCs? (4)
- Aplastic anemia
- Pernicious anemia
- Folate deficiency anemia
- Blood loss or hemorrhagic anemia
What types of anemia is related to Hb? (2)
- Iron deficiency anemia
2. Sickle cell anemia
Aplastic anemia
Decreased numbers of RBCs following destruction of hemopoietic elements in the bone marrow
Why does aplastic anemia occur? (4)
- Toxins
- Certain drugs
- High dose irradiation
- Chemotherapy
How can you treat aplastic anemia?
Bone marrow transplants
Pernicious anemia
Decrease numbers of RBC
What causes pernicious anemia? (2)
- Dietary deficiency of B12
2. Deficiency of intrinsic factor
What does deficiency of the intrinsic factor lead to?
Decreased absorption of vitamin B12