A&P - Chapter 27 (Part 3) Flashcards
Polycythemia
Bone marrow produces too many RBCs leading to an abnormally high RBC count
What is dangerous about polycythemia?
Blood may become too thick and not flow properly
What can polycythemia result in? (2)
- Stroke
2. Heart attack
What is the opposite of polycythemia?
Anemia
Erythropoeisis
Formation of RBCs
How long does it take for the maturation process of hemocytoblast to matured RBC?
4 days
Where does the formation of RBCs begin?
In the red bone marrow
Why do RBCs have to be continually replaced?
Because they are continually destroyed
How many RBCs are created/destroyed everyday?
200 billion
What is the average lifespan of a circulating RBC?
105-120 days
How do we get rid of RBCs?
Through macrophages in the liver and spleen
What do macrophages try and do?
Recycle old, abnormal and broken down RBCs
What is released when Hb is broken down? (3)
- Amino acids
- Iron
- Bilirubin
What are the 2 main types of systems by which human blood can be classified?
- ABO systems
2. Rh systems
ABO system
Blood types are identified by self-antigens in the plasma membranes of RBCs