Quesmed arthritis Flashcards
Which type of arthritis has no systemic manifestations?
Osteoarthritis
What is the most common cause of septic arthritis?
Staphylococcus aureus, typically from haematogenous spread due to abscess
What is the most common cause of septic arthritis in sexually active young people?
Neisseria gonorrhoea
What are the features of septic arthritis?
Acute swollen joint, (knee in adults) which is warm to the touch and fever.
What is rheumatoid factor?
IgM reacting against IgG
Rhomboid crystals
Calcium pyrophosphate
What do thiazide diuretics increase risk of?
Gout
What increases Uris acid levels?
Cytotoxic drugs like chemotherapy
High cell turnover
Severe psoriasis
How does inflixmab work?
Anti-TNF monoclonal antibody to reduce macrophage release for inflammation
Reduces tumour activity and is used in CML
What is psoriasis?
Mediated by Th1 cells and affects extensor aspects, which is improved in sunlight, It can cause nail pitting and on hypnosis.