B13 Formative Feedback Flashcards
What is Verampil?
Class IV anti-arrythmia which is a L-type calcium channel blocker that slows the plateau phase in an action potential. They reduce inotropy and are used to treat supraventricular tachycardia. However, it would worsen cardiac failure
When is staphylococcus aureus cause pneumonia?
After viral infection and it causes bronchopneumonia.
What is digoxin used to treat?
Atrial flutter.It increases intracellular Ca2+ and has a positive inotropic effect but stimulates the vagus nerve to reduce heart rate. This occurs because there is inhibition of the na+/K+ ATPase which increases activity of the Na/Ca2+ exchanger.
What are ACE inhibitors a prophylaxis for?
Ischaemic heart disease- side effect of ACE inhibitors is first dose hypotension.
Does COPD prevent inspiration or expiration?
Limits expiration which leads to hyperinflation.
What do multiple lesions in the lungs indicate?
Metastatic lung cancer,
What is sarcoidosis?
Multisystem inflammation where there is granuloma formation in multiple areas of the body.THis may lead to hilar lymphadenopathy.
What is legionella pneumonia?
Typically transmitted through tubs through water and the only type of pneumonia that causes hyponatremia.
How is a STEMI myocardial infarction treated?
Complete block of coronary artery so there is thrombolytic therapy and primary Percutaneous coronary intervention.
How is a non-STEMI myocardial infarction treated?
Partial block of coronary artery so there is treatment with:
Antiplatelet therapy, low molecular weight heparin, statins and anti-ischaemic drugs.
This is done to maintain perfusion.
What is a bio marker for thrombosis?
D-dimers, which are protein fragments made when a blood clot dissolves.
What drug will inhibit thrombus formation?
Streptokinase which causes cleavage of plasminogen -> plasminogen to break down the clot.
What is the role of plasmin?
Break down blood clots.
