B15 Drugs: Steroid Drugs

Question 1

What is hydrocortisone?

Answer 1

Corticosteroid given for ulcerative colitis and adrenocortical insufficiency due to Addison’s disease or thyrotoxic shock. It reduces the production of pro-inflammatory mediators and promotes the production of pro-inflammatory mediators.

It should be avoided with active infection and leads to Cushing’s syndrome, anxiety and muscle wasting and osteoporosis.

Question 2

What is Fludrocortisone?

Answer 2

Mineralcorticoid which is given for adrenocortical insufficiency such as salt-wasting congenital hyperplasia or Neuropathic postural hypotension.

It causes bloating, hypertension, hypokalemia and muscle wasting. Should be avoided in active infection.

Question 3

What is Beclamethasone?

Answer 3

It is an inhaled corticosteroid given for asthma, allergic rhinitis and allergic skin conditions. It reduces the production of pro-inflammatory mediators.

Side effects are increased risk of pneumonia with COPD, voice alteration and oral candiadis. Should be avoided in active nasal infection or pulmonary tuberculosis.