Harvluck B11 W1 Flashcards

1
Q

What is the decidual septa?

A

Decidua is the modified endometrium that projects into the intervillous space to form septa and divide the placenta into cotyledons, maximising nutrient exchange. The decidual septa contain a core of maternal tissue and are surrounded by synctial cells.

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2
Q

What happens to DNA at conception?

A

Undergoes methylation- acetylation must occur to allow cells to differentiate.

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3
Q

Cumulus cells

A

Derived from granulosa cells

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4
Q

What forms the surface of the chorionic villi in first trimester?

A

Synctiotrophoblast

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5
Q

When is abdominal palpation offered in pregnancy?

A
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6
Q

Parthenogenetic activation

A

Egg activated in absence of a sperm

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7
Q

Precursor to yolk sac

A

Hypoblast

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8
Q

PLuriblast

A
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9
Q

What causes the blastocyt to expand?

A

Na=/K+ ATPase pump

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10
Q

Intracyptoplasmic sperm injection

A

Injecting sperm cell directly into the egg for men with fertility issues.

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11
Q

Foetal surface of placenta

A

Chorionic plate

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12
Q

Maternal surface of placenta

A

Decidua

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13
Q

Colour of pregnancy notes book

A

Green

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14
Q

Decidua basalis

A

Portion of decidua connected to the chorion

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15
Q

pO2 in foetal blood

A

0mmHg

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16
Q

How long after fertilisation does implantation occur?

A

6-12 days after ovulation

17
Q

How does oestrogen affect blood volume?

A

Releases nitric oxide for vasodilation, increases angiogenesis and venous distensibility. Increases Levels of angiotensin II.

18
Q

When is foetus larger than placenta?

A

17 weeks

19
Q

When does placenta perform endocrine role?

A

Second trimester
Aromatises androgens to produce oestrogen
Produces progesterone
hCG
Somatomammotrophin

20
Q

Where do ectopic pregnancies implant?

A

Ampulla of Fallopian tube

21
Q

How does the egg prevent polyspermy?

A

Membrane depolarises and zona pellucida hardens in the cortical reaction. This occurs when it fuses with the sperm’s membrane.

22
Q

What regulates invasion of trophoblast cells?

A
23
Q

What erodes maternal tissue to access blood supply?

A

Synctiotrophoblasts- they erode the primary decidua, which are the cells underlying the endometrium

24
Q

Nuclear material of cytotrophoblasts

A

Mononuclear

25
Q

Where does embryo implant?

A

Utero-tubule junction

26
Q

Role of mucin

A

Anti-adhesive protein for the hatching of blastocyst from the glycocalcyx.

27
Q

Perivitelline space

A

Located between membrane of egg and zona pellucida

28
Q

Trimester where nervous system develops of foetus

A

Trimester 2

29
Q

What interdigitates with uterine epithelia?

A

Villous trophoblast

30
Q

Female infertility

A

Ovulatory disorder, tubular disease, endometriosis

31
Q

Hormones which increase maternal insulin resistance

A

Prolactin
Cortisol
Human placental lactogen

32
Q

Effect of progesterone on hypothalamus

A

Increases action of thirst centre for aldosterone release

33
Q

First ultrasound scan

A

13-14 weeks

34
Q

Amnion components

A

Endoderm and mesoderm

35
Q

Terminal villi

A
36
Q

Foetal lobule

A

Converted spiral artery

37
Q

Triploidy type 2
Triploidy digynic

A
38
Q

UK fertility rate

A
39
Q

What causes urinary stasis?

A

Relaxation of ureter and bladder due to effect of progesterone