Harvluck B11 W1 Flashcards

1
Q

What is the decidual septa?

A

Decidua is the modified endometrium that projects into the intervillous space to form septa and divide the placenta into cotyledons, maximising nutrient exchange. The decidual septa contain a core of maternal tissue and are surrounded by synctial cells.

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2
Q

What happens to DNA at conception?

A

Undergoes methylation- acetylation must occur to allow cells to differentiate.

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3
Q

Cumulus cells

A

Derived from granulosa cells

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4
Q

What forms the surface of the chorionic villi in first trimester?

A

Synctiotrophoblast

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5
Q

When is abdominal palpation offered in pregnancy?

A
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6
Q

Parthenogenetic activation

A

Egg activated in absence of a sperm

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7
Q

Precursor to yolk sac

A

Hypoblast

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8
Q

PLuriblast

A
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9
Q

What causes the blastocyt to expand?

A

Na=/K+ ATPase pump

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10
Q

Intracyptoplasmic sperm injection

A

Injecting sperm cell directly into the egg for men with fertility issues.

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11
Q

Foetal surface of placenta

A

Chorionic plate

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12
Q

Maternal surface of placenta

A

Decidua

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13
Q

Colour of pregnancy notes book

A

Green

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14
Q

Decidua basalis

A

Portion of decidua connected to the chorion

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15
Q

pO2 in foetal blood

A

0mmHg

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16
Q

How long after fertilisation does implantation occur?

A

6-12 days after ovulation

17
Q

How does oestrogen affect blood volume?

A

Releases nitric oxide for vasodilation, increases angiogenesis and venous distensibility. Increases Levels of angiotensin II.

18
Q

When is foetus larger than placenta?

19
Q

When does placenta perform endocrine role?

A

Second trimester
Aromatises androgens to produce oestrogen
Produces progesterone
hCG
Somatomammotrophin

20
Q

Where do ectopic pregnancies implant?

A

Ampulla of Fallopian tube

21
Q

How does the egg prevent polyspermy?

A

Membrane depolarises and zona pellucida hardens in the cortical reaction. This occurs when it fuses with the sperm’s membrane.

22
Q

What regulates invasion of trophoblast cells?

23
Q

What erodes maternal tissue to access blood supply?

A

Synctiotrophoblasts- they erode the primary decidua, which are the cells underlying the endometrium

24
Q

Nuclear material of cytotrophoblasts

A

Mononuclear

25
Where does embryo implant?
Utero-tubule junction
26
Role of mucin
Anti-adhesive protein for the hatching of blastocyst from the glycocalcyx.
27
Perivitelline space
Located between membrane of egg and zona pellucida
28
Trimester where nervous system develops of foetus
Trimester 2
29
What interdigitates with uterine epithelia?
Villous trophoblast
30
Female infertility
Ovulatory disorder, tubular disease, endometriosis
31
Hormones which increase maternal insulin resistance
Prolactin Cortisol Human placental lactogen
32
Effect of progesterone on hypothalamus
Increases action of thirst centre for aldosterone release
33
First ultrasound scan
13-14 weeks
34
Amnion components
Endoderm and mesoderm
35
Terminal villi
36
Foetal lobule
Converted spiral artery
37
Triploidy type 2 Triploidy digynic
38
UK fertility rate
39
What causes urinary stasis?
Relaxation of ureter and bladder due to effect of progesterone