Conditions Of The Eye: Glaucoma, Cataracts And Colour Blindness Flashcards

1
Q

How does the eye drain fluid?

A

Aqueous humour is produced in the anterior cavity of the eye by the ciliary processes using carbonic anhydrase. This drains down the trabecular mesh work to the canal of Schlemm, which is connected to anterior ciliary veins. The intraocular pressure is a measure of the resistance of flow of aqueous humour in the trabecular mesh work.

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2
Q

What is the anterior chamber of the eye?

A

Space between the cornea and the iris containing aqueous humour.

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3
Q

What is the posterior chamber of the eye?

A

Space between the iris and the optic disc containing vitreous humour.

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4
Q

What is chronic glaucoma?

A

Open angle glaucoma caused by resistance to flow of aqueous humour in the trabecular mesh work, with a large angle between the iris and lens in the anterior chamber and results in increased intraocular pressure.

There is a slow and gradual onset that causes loss of peripheral vision, headaches and gradual vision loss generally that is worse at night. Cupping of the optic disc occurs.

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5
Q

What are the risk factors for open angle glaucoma?

A

Myopia (shortsightedness)
Family history
Hypertension due to previous chronic conditions such as diabetes
Long term corticosteroid use
Eye injury

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6
Q

What is acute glaucoma?

A

Chronic glaucoma which is an opthalmagic emergency caused by the iris bulging forward and creating a reduced angle from the lens that blocks the trabecular mesh work for drainage of the aqueous humour. There is painful red eye and blurred vision which progresses to nausea and vomiting.

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7
Q

What is glaucoma?

A

Increased intraocular pressure caused by resistance to aqueous humour flow in the trabecular meshwork that can lead to damage to the optic nerve.

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8
Q

What are the risk factors for closed angle glaucoma?

A

Older Age, Female, East Asian, Family history.

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9
Q

What is the treatment of open angle glaucoma?

A

Prostaglandin analogues which induce vasodilation
Beta blockers which will reduce aqueous humour production.
Carbonic anhydrase inhibitors which reduce aqueous humour production
Sympathomimetics which reduce aqueous humour production and increase flow out of the eye.

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10
Q

What is the treatment of closed angle glaucoma?

A

Carbonic anhydrase inhibitors to induce reduction of aqueous humour production.

Pilocarpine eye drops, a miotic which activates the parasympathetic system for reduction in pupil size and opens channels in the trabecular meshwork and induces fluid to drain from the eye

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11
Q

Which type of glaucoma is more common?

A

Primary open angle glaucoma.

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12
Q

What is cataracts?

A

Opacity of the lens due to degeneration of the proteins, such as the modified epithelial cells which make it up or the lens capsule. It results in vision loss and is the leading cause of blindness worldwide. With cataracts, secondary vision phenomenon can occur where there is correction of previous myopia.

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13
Q

Who is most commonly affected by cataracts?

A

Older people
Caucasian
People with endocrine disorders such as diabetes

Men and women are equally affected

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14
Q

What are the risk factors for cataracts?

A

Smoking
Alcohol
Previous eye trauma
UV radiation
Trauma
Diabetes

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15
Q

How is cataracts treated?

A

Surgical removal of lens and replacement with artificial lens.

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16
Q

How is glaucoma diagnosed?

A

Tonometry to measure the intraocular pressure.
->In the optic disc, there is a tiny centre called the optic cup. Because of death of nerve cells in glaucoma, the optic cup becomes larger in comparison to the disc.

Visual perimeter.

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17
Q

What is visual perimetry?

A

Measures field of vision for any peripheral loss.

18
Q

What is uveosscleral outflow?

A

Alternative less common route for aqueous humour to drain out of the eye into a space between the sclera and the choroid

19
Q

Which drugs reduce aqueous humour inflow?

A

Beta blockers
Carbonic anhydrase inhibitors
Alpha agonists

20
Q

Which drugs increase uveroscleral outflow?

A

Prostaglaindin agonists.

21
Q

Which drugs increase trabecular outflow?

A

Muscarinic agonists.

22
Q

What increases aqueous humour inflow/production?

A

Beta agonists and alpha blockers.

23
Q

What increases aqueous humour outflow?

A

Via trabecular meshwork with muscarinic agonists
OR
Via uveoscleral pathway using prostaglandins analogues

24
Q

What are the types of cone cells?

A

Contains
S-type cells for blue vision, encoded by Chromosome 7
L-type cells for red vision, encoded by X chromosome
M-type cells for green vision, encoded by X chromosome.

25
Q

What is the most common type of colour blindness?

A

Red-greeen colour blindness, an X linked recessive condition that typically affects males.

26
Q

What are the categories of colour blindness?

A

Dichromat
Anomalous trichromatic

27
Q

What is dichromatic colour blindness?

A

Only 2 cone cells are functional.
Includes pronatopia, deutaranopes and tritanopes.

28
Q

What is protanopia?

A

Type of dichromatism where there is red light insensitivity. It is the most common type of colourblindness which is X linked.

29
Q

What is deutaranopia?

A

Type of dichormatism where there is absence of M cones for green light.

30
Q

What is tritanopes?

A

Type of dichromatism where there is an insensitivity to blue light due to absence of S cones, caused by chromosome 7 mutation.

31
Q

What is anomalous trichromatism?

A

There is presence of all 3 cone types but a specific cone type has abnormal spectrum, with a range of severity.
Protanomous trichromatism: L type
Deutaranomous trichromatism: M type
Tritanalamous trichromatism: S type

32
Q

Which nerve controls the pupillary sphincter?

A

Oculomotor nerve.

33
Q

What is the angle of the eye?

A

Space between the iris and lens.

34
Q

Vision worse looking down

A

Trochlear Nerve Palsy which affects the superior oblique

35
Q

Which extraocular muscle has contralateral innervation?

A

Superior rectus
Superior oblique

36
Q

Ipsilateral innervation of extraocular muscles

A

Medial rectus
Inferior rectus
Inferior oblique
Lateral

37
Q

Which cranial nerve is anterior to olives of medulla?

A

Hypoglossal

38
Q

What is the visual cortex pathway??

A
39
Q

What is the nasal field of vision?

A
40
Q

What is the temporal field of vision?

A