Peds Final Flashcards

1
Q

Define APGAR

When/why would these be repeated

Why is this done at two different time intervals

A

Appearance:
0- cyanotic 1- Acrocyanosis/blue extremity 2- all pink

Pulse:
0- none 1- <100bpm 2- >100bpm

Grimace w/ nare suction:
0- none 1- grimace/cry 2- sneeze/cough/withdraw

Activity:
0- limp/none 1- some flexion 2- active

Respiration:
0- none 1- weak/slow/irregular 2- strong cry

Rpt q5min if score <8 (max of 10)

1min: tolerance of birth
5min: tolerance to life

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2
Q

Newborn respiratory rate

Newborn HR

What are the next steps taken for abnormal HR ranges

A

30-60/min w/ inc number if premature

120-160

> 100: routine care
60-99: ventilation support
<60: ventilation w/ compressions

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3
Q

What is the compression/ventilation ratio during NRP

How do premature/neonates respond to hypoxia

What is the positioning and rate of ventilations when using BVM

A

3 compression : 1 respiration
Two thumbs > two fingers

Apnea rather than tachypnea

Sniffing position (neck w/ slight extension), 40-60 bpm

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4
Q

What is the next step if infant’s chest fails to rise w/ BMV

When is this next step preferred

What fluids are used during NRP

A

Intubation

Transport

10mL/kg NS for hypo-volemia/tension

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5
Q

What is the next step for asystole/bradycardia unresponsive to O2

Rules for Narcan usage in newborns

? care is routine for all infants and w/ ? goal

A

IV Epinephrine

Only if opiates used during labor
Not if maternal addict or methadone use d/t withdrawal seizures

Nursing- prevent illness/complications w/ high level of morbidity/mortality

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6
Q

What are the two categories of standard nursery care and what is done during each

Which test is state mandated

A

A) Shortly after:
Erythromycin ointment- G/C conjunctivitis
Vit K injection- Hemorrhagic Dz of Newborn
HBV- only vaccine given at birth

B) 24hr Routine Care:
Bilirubin screen
Congenital heart screening
Gene/Metabolic screen (AKA- newborn screen)
Hearing

Genetic/Metabolic:
CF CAH PKU Sickle TSH

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7
Q

Congenital heart dz screening is done at 24hrs of life/before d/c and is interpreted how

A

Spo2 95% or higher w/ 3% or less difference between right hand/foot= negative screening, plan for d/c

SpO2 90-94% in right hand/foot or 3% difference= repeat in one hour; same results- repeat again in one hour; 3 readings in same range= echo

SpO2 <90% in right hand/foot= +screen- order Echo

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8
Q

Infant length is done in ? position until ? time frame and when are inaccurate measurements most likely to occur

Criteria for Low/Very Low birth weights

What are the RFs for LBW

A

Laying down until 2yrs old;
First week d/t positioning

Low: <2500gm; Very: <1500gm

Previous LBW baby
Age <16, >35
Socioeconomic status
Tobacco/ETOH/Drugs
Poor weight gain during pregnancy
Education
No antenatal care
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9
Q

During newborn exam, an anterior fontanelle bigger than ? size suggests ? issue

An absence and totally closed suggests ?Dx

Define Caput Seccedaneum

A

Anterior suture >5cm- hypothyroid

Craniosynostosis

Boggy, edematous swelling crossing lines, self resolves

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10
Q

Define Cephalohematoma

? head malformation is associated w/ vacuum deliveries and how is it Tx

Define Hydrocephalus and the two types

A

Leads to RBC breakdown/jaundice causing swelling w/out crossing suture lines

Subgleal hemorrhage- swelling crosses suture lines, pushes ears anteriorly;
Tx: Compression w/ resuscitation PRN

Inc CSF volume;
Communicates w/ subarachnoid/Obstructed

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11
Q

How does Hydrocephalus present

How is this Tx

What can cause an abnormal red reflex on newborn eye exam

A

Bulging fontanelles
Macrocephaly
Setting sun gaze

Ventriculoperitoneal shunt

Leukocoria: cataract, tumor, retinopathy of prematurity

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12
Q

What optic abnormality can be normal on a newborn exam until 4mon old

What considered normal/abnormal ear positioning

Define Epstein Pearls and Bohn Nodules

A

Disconjugate gaze d/t failure of eyes to move in same direction

1/3 above canthus/occipital protuberance
20* from anterior of lobe to superior helix

EP: Keratin cysts on gums/palate
BN: Keratin cysts on salivary tissues

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13
Q

When conducting new born exams, how do neck bulge locations hint at Dx

How are lower extremity pulses assessed during newborn exam

? abdomen shape suggests diaphragmatic hernia

A

Anterior midline: thyroid d/o
Anterior to SCM: brachial cleft cyst
Posterior to SCM: cystic hygroma

Brachial and femoral together:
Pulse pressure >40mm= r/o PDA
LE < UE pulse= r/o coarctation

Scaphoid

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14
Q

What do each of the following suggest for cardiac d/o/dz

Weak pulse

Bounding pulse

Single second sound

Holosystolic, continuous, harsh

Grade 3/>

Diastolic murmur

Hempatomegaly

A

Weak: poor CO/AS

Bounding: high CO, PDA

Second sound: cyanotic dz- truncus/hypoplastic heart

Holosystolic, continuous, harsh- pathologic

Grade 3/>: pathologic

Diastolic: pathologic

Hempatomegaly: left sided HF

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15
Q

? umbilical finding suggests need for detailed exam

Umbilical cord stump remaining longer than ? needs further work up

? DDxs need to be r/o if red granuloma/stump remnants remain

A

Two vessels: 1 artery, 1 vein instead of normal 2A/1V but no referral needed

1mon

Umbilical polp: sticky surface
Patent Urachas: urinary d/c
Meckels: proximal end of vitelline duct
Vitelline duct: odorous d/c

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16
Q

Since all infants are born w/ limited laxity, what are the three concerns if this persists

RFs for Congenital Hip Dysplasia

A

L > R w/ risk for changes including:
Flat acetabulum
Muscle contraction limiting ROM
Capsule tightening

Female First FamHx
Oligohydramnios
Breech
Swaddling- hips adduct/extended

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17
Q

Define Barlow Maneuver

Define Ortolani Maneuver

If ‘clunk’ is heard, ? is the next step

A

Hipp adduction, forward pressure w/ thumb- can cause femoral head to slip over posterior rim of acetabulum

Flex hips to 90*, abduct hip w/ anterior push/lift of trochanter; resets joints

Hip US at 4-6wks to avoid confusion w/ normal laxity

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18
Q

Congenital Hip Dysplasia referred to Peds Ortho will be placed in ? device for ? age groups

? is the MC foot d/o in infants and what are they at risk for developing ? later in life

How is this MC Dx

A

Pavlik harness- up to 6mon old

Metatarsus adductus- medial deviation of mid and forefoot;
Developmental hip dysplasia

Mid-heel bisector- line between toes 2-3
V-finger- no gap at base of 5th MT (styloid)

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19
Q

How are Metatarsus Adductus cases Tx

Define Talipes Equinovarus

What part of the leg is MC affected and what does this cause

A

Self-resolve, if not w/in 2yrs= Ortho referral

Clubfoot- entire leg involved d/t hypoplastic tarsals and limb muscles

Talus, causes foot shortening/calf atrophy

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20
Q

All cases of Clubfoot need to have ? DDx assessed for

What is a common abnormal seen on fe/male GU exam of a newborn

Define Spina Bifida

A

Hip dysplasia

Retractile testes, Hypertrophy labias

AKA Cleft Spine: Lumbosacral hair tuft concerning for spinal cord defects

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21
Q

When/How is Spina Bifida normally identified during pregnancy

Define Rachischisis and ? risk needs to be r/o

What are the categories of Spina Bifida

A

2nd-Trimester quad screen- maternal A-fetoprotein and fetal US

Spina Bifida Occulta- hair tuft/minor defect w/out neuro S/Sxs;
r/o connecting sinus d/t inc risk for meningitis

Meningocele- meninges herniates through neural arch
Meningomyelocele- meninges and cord herniate through neural arch
Myeloschisis- open skin w/ cord exposed

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22
Q

What are the primitive reflexes tested for on newborn exam

What do these reflexes evaluate

When do these normally disappear

A

Suck Moro Grasp

Brain stem, Basal ganglia

4-6mon d/t increased cerebral inhibition of cerebral influences

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23
Q

Only reflex not present at birth and never disappears

What reflexes disappear at 3, 4, 6 or 12mon

Facial palsy in newborn is associated w/ ?

A

Parachute- appears at 8-10mon; suspended face down, move towards table causes arm extension for protection

3: Asymmetric tonic neck
4: Rooting Placing Gallant
6: Moro Grasp
12: Babinski

Forcep delivery

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24
Q

Define the MC brachial plexus lesion

What reflex is present/absent in this MC

Define Klumpke Palsy and what reflexes are present/absent

A

Erb-Duchenne/Waiter’s Tip- C5/6/phrenic nerve lesion d/t shoulder dystocia

+ grasp, - bicep

C8-T1 lesion;
- grasp +bicep w/ claw hand

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25
Q

What syndrome is associated w/ Klumpke Palsy if a cervical sympathetic nerve root was injured

Define Vernix Caseosa

When is term infant desquamation typically seen

A

Ipsilateral Horner’s Syndrome

Chalky white mixture of shed epithelials cells, sebum, keratin and hair; common in preterms for suspected fetal protection

24-48hrs of life

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26
Q

Define Milia

Define Milia Rubra

Define Cutis Marmorata

A

Smooth, white papules on face/scalp d/t trapped keratin; self limited/resolves 1-4wks

Heat rash d/t overheated/febrile infant w/ erythematous papules; Tx/correct overheating

Mottling- cold response; persistent suggests hypothyroidism/vascular malformation

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27
Q

Define Slate Gray Nevi

Define Cafe Au Lait macules and when are further work ups indicated

Nevus Simplexes are AKA ?

A

Transient dark macule on lower back/buttocks that fade w/ time

Sharply defined, pigmented macules;
6 or more/ 5cm or bigger to r/o NF-1, TB, McCune Albright Syndrome

Salmon patches
Stork bite- nape of neck
Angel kiss- forehead/eyelids

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28
Q

Define Nevus Flameus

? syndrome needs to be r/o depending on location

Define Erythema Toxicum Neonatorum

A

Port Wine Stain; d/t capillary bed malformation

Sturge Weber Syndrome if trigeminal nerve distribution

Pustules w/ erythematous base on trunk appearing 1-2 days after birth, resolves in 14days

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29
Q

What would be seen on microscopy slide of Erythema Toxicum Neonatorum

RFs for neonatal sepsis

Primitive reflexes are usually gone by ? age

A

Eosinophils

Prematurity
GBS
Fetal tachy
Amnionitis
Maternal fever
PROM

4-6mon

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30
Q

Neonatal sepsis etiologies w/ early onsets

Neonatal sepsis etiologies w/ late onsets

A
Mycoplasma
GBS- MC/#1
Klebsiella
Listeria
E coli
Salmonella

Hflu Neisseria CMV HSV Enterovirus
Strep Staph

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31
Q

Early onset neonatal sepsis begins on ? day and presents w/ ?

Late onset neonatal sepsis begins on ? day and is more likely associated w/ ?

A

Fast onset of F/C/HOTN, hypotonia, respiratory distress

Insidious onset on day 8-28:
Bulging fontanelle
Direct hyperbilirubinemia
Seizure
Lethargy
Fever
Poor feeding/tone
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32
Q

What orders are needed for a neonatal sepsis work up

How are these Pts Tx

What two meds may be added after further eval/based on etiology

A
Glucose 
CXR 
CBC
LP 
UA w/ culture 
Blood culture x 2

Draw labs, IV fluid, nutrition and:
IV Ampicillin w/ Genamicin
>3wks old: IV Ampicililn w/ Cefotaxime

Vancomycin: late onset/meningitis
Acyclovir- HSV infection

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33
Q

Three steps for newborn of GBS positive mother

A

1: infant have S/Sxs?
Yes: eval w/ empiric Tx
No: step 2

2: infant <35wks EGS?
yes; limited eval w/ 48hr observation
no: step 3

3: Two maternal ABX doses prior to delivery?
Yes: no eval/therapy, observe x48hrs
No: limited eval w/ 48hr observation

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34
Q

? PE finding is a sign of neonatal respiratory distress

What are 3 possible Dxs that can cause this PE finding

Respiratory Distress Syndrome is AKA ? and caused by ?

A

Grunting (can sound like meowing)

Dec functional residual capacity:
Pneumonia
Pulmonary edema
Peripheral airway obstruction

Hyaline Membrane Dz: dec surfactant from Type 2 pneumatocytes in <34wks EGA

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35
Q

RDS results in ? and looks like ? on CXR

How is RDS Tx prior to birth

How is RDS Tx after birth

A

End expiration atelectasis; Ground glass

Maternal steroids 32-34wks EGA

Intubation w/ surfactant/support via ET tube

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36
Q

What complications can arise from RDS

A

PDA: day 2-4 w/ L-R shunt (systemic to pulm) as pulmonary edema/hepatomegaly;
Tx: Fluid restriction w/ diuretic/NSAIDs

PTX- Sxs get chest tube

Bronchopulmonary dysplasia- caused by O2 toxicity/barotrauma

Retinopathy of prematurity- O2 toxicity vasoconstricts developing vessels= obliteration/blindness (term infant eyes fully vascularized- no risk)

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37
Q

What are the 3 RFs for Bronchopulmonary Dysplasia after RDS

Criteria for Apnea of Prematurity

What are the two types and causes

A

O2 dependence at 36wks old
RDS persists >14days
Prolong mechanical ventilation

10-20sec w/out pulmonary airflow

Central: medulla/pons don’t stimulate phrenic nerve (common in prematures)
Obstructive: malformation/positional

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38
Q

Apnea of Prematurity is traditionally ? type

How are Pts managed/Tx

? is the MC congenital tracheal abnormality

A

Central w/ peripheral component

O2, Stimulants: caffeine/theophylline

Tracheomalacia- floppy trachea worse during expiration (harsh, monophonic wheeze/normal voice/inspiration)

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39
Q

Four possible outcomes from Meconium Aspiration Syndrome

How are non-vigorous babies w/ aspiration managed

How does aspiration appear on CXRs

A

Respiratory distress
Pneumo-nia/nitis/thorax

Suction mouth/trachia
Unsuccessful: BVM w/ PPV

Coarse, irregular infiltrates predisposes Pt to pneumonia/Ptx

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40
Q

What causes Transient Tachypnea of the Newborn

How would this appear on CXR

When is this type of issue more commonly seen

A

Retained amniotic fluid causes hypoxia that resolves <24hrs

Fluid in fissures

C-section, LGA d/t no ‘squeeze’ during birth

41
Q

What are the two forms of P-HTN in term infant that can cause respiratory distress

MCC of Hemolytic Dz of newborn

What are the three reasons all newborn have an elevated bili

A

Primary: Hypoxia w/out CV dz + normal CXR
Non-Primary: induced L to R shunt

ABO incompatibility

Inc RBC turnover
Dec hepatic clearance/gut motility

42
Q

Neonatal hyperbilirubinemia is defined as ? levels

? is the MCC of neonatal jaundice

Define Kernicterus

A

Total Bili >5mg/dL

Hemolytic Dz of the newborn- ABO incompatability is MCC

Bilirubin Encephalopathy- indirect bili deposits in brain, disrupts neurons

43
Q

Early signs of Kernicterus

Late signs of Kernicterus

MC classification of hyperbilirubinemia

A
Day 4 of life w/:
Lethargy
Emesis
Hypotonia
High pitch cry
Irritable
Poor Moro/feeding
Fever
Hypertone
Bulging fontanelle
Opisthotonic posture
Pulmonary hemorrhage
Paralysis of upward gaze
Seizures

Unconjugated, estimated w/ indirect level

44
Q

What causes Physiological Jaundice to occur

What causes Breastfeeding Jaundice

A
Breastfeeding
Premature
Altitude >3100m doubles risk
Inability to excrete/conjugate/degrade bili
Race: Asian/Mediterranean

Inadequate feeds causing dec gut motility
Dec production/intake

45
Q

What causes Breastfeeding Jaundice if adequate feedings are taking place

What lab result would be seen in these cases

Jaundice seen at ? point in time is always pathologic

A

Milk contains inhibitor of bilirubin conjugation and inc hepatic recirculation

Unconjugated hyperbilirubinemia w/out hemolysis

1st day of life

46
Q

How could Pathologic Jaundice present in house

When evaluating jaundice, ? is the first location that needs to be assessed

? is first line test ordered for evaluation of neonatal jaundice

A

Unresponsive to phototherapy or transfusions

Under tongue THEN sclera then down towards toes

Transcutaneous then serum bili

47
Q

How is Neonatal Jaundice Tx if Mild, Mod or Severe

What are the short and long term adverse effects of neonatal phototherapy

A

Mild: lifestyle, breast feed, sunlight
Mod: photo therapy
Sev: exchange transfusion if levels >20

Short:
Diarrhea/GI hyper-motility
Dec bonding
Temp instability

Long:
Asthma, DMT1

48
Q

What is included in a standard well visit

Define Neonate

Define Infant

Define Toddler

Define Pre-Schooler

Define Child

Define Adolescent

A

Growth Development Imms Guidance Screenings

N: 0-28d old

I: 29d-1y/o

T: 1-3y/o

P: 2-5y/o

C: generic for 1-12y/o

13-18y/o

49
Q

Define Growth and Development

Developmental Scales are AKA ? and use ? as more more detailed screening

Define Developmental Milestones

A

G: increase in body size
D: increase in function/process

Ages and Stages;
Denver Developmental Screening Test 2

Observable traits/actions that present/fade at predictable ages

50
Q

What is the MCC of abnormal growth chart results

What are the pros/cons of developmental scales

What are the pros/cons of developmental milestones

A

Operator error

P: Accurate Reproducible
C: Time Tools

P: Fast Easy
C: Experience Judgement

51
Q

What growth charts are used from birth-2y/o and are more accurate for ?

What growth charts are used from 2-20y/o and also account for ? three factors

How much weight loss expected during first few days of life

A

WHO charts; breast fed infants

CDC; Place Obesity Time

5-10% of birth weight

52
Q

Time frame to return to birth weight, double and triple their weight

What is considered normal daily weight gain

By 4y/o, average child length has increased by ? much

A

Return by day 14
Double 4-5mon
Tripled birth weight by 12mon

20-30g x first 3-4mon
15-20g x remainder of first year

Double birth length or, 40”

53
Q

Average head circumference at birth is ? and increases by ? much

Pediatric weight percentiles/categories

How are heights predicted for fe/males

A

35cm at birth
Inc 1cm/mon x first 12mon (2cm/mon first 3mon)

<5th: underweight
5-85th: normal
85-95th: over weight
>95th: obese

Mid-Parental Method:
M: Paternal + Maternal/2 + 2.5
W: Paternal + Maternal/2 - 2.5

2-year x 2 Method:
Height inches at 2y/o x 2

54
Q

What is the most accurate method for predicting height

MC factor affecting growth

Babies born small/premature can be expected to go through ‘catch up’ growth during ? frame

A

Bone age w/ hand x-ray

Nature: Hereditary factors

First 6mon

55
Q

When is medical interventions indicated for deficient growth patterns

Half of a child’s growth occurs during ? period of life and then declines

Nutrition/growth during ? pat of life predict adult stature and health outcomes w/ the most risk for stunted growth being at ?

A

<5% w/out cause
Crosses two percentile lines w/out cause
Discrepancy between Head/Weight/Length

First two years

First 3yrs;
4-24mon

56
Q

It is recommended breast milk as sole nutrition source for premature infants d/t ? benefits

What can be used for Vit D/Fe supplementation for breast feeding mothers

Absolute c/is to breast feeding

A

6mon;
Lower readmission rates
Long term IQ development

Polyvisol

Radiopharmaceuticals
Alcohol: <0.5g/kg
Maternal infection: HIV Active TB H1N1 HSV on breast Varicella
PCP Amphetamines Cocaine

57
Q

What are the three categories of formula

A

Cow milk based:
Fortified w/ Fe, no sterilization needed

Soy based:
Non-lactose alternative w/ possible isoflavone effect

Casein hydrolysate:
Used when absorption/digestion problem exists, $$

58
Q

What is the difference between Surveillance and Screening visits

When are the standard time frames to conduct screenings

What is used for Autism screening and when is it performed

A

Surveillance: ongoing at any visit
Screen: formalized at prescribed times

9, 18 and 24mon

M-CHAT-R at 18 and 24mon;
>2 predictive or >3 total= further eval

59
Q

How are ASQs used for infants born premature?

What are the 5 developmental areas of the ASQs

A

Corrected date of birth if more than 3wks premature up to 2y/o

Problem solving
Communication
Motor
Personal/Social

60
Q

Milestones for 2mon

Milestones for 4mon

Milestones for 6mon

Milestones for 9mon

Milestones for 12mon

Milestones for 15mon

Milestones for 24mon

A

2: Shoulder lift when prone, tracks past midline, smiles and cooes
4: Rolls over, no head lag, reaches for objects, looks at hand, laugh/squeal
6: Sits alone, transfer objects, feeds self, babble
9: Pulls up, pincer grasp, bangs objects, waves/patty cake, two-syllable words
12: Walks, Stacks, Immitates,
15: walks backwards, scribbles, Spoon/Fork, 3-6word sentences
24: Stairs, washes hands, understands ‘today’

61
Q

What are the red flags for Gross Motor

What are the red flags for Language

A

Rolling <3mon old= inc tone
Poor head control at 5mon= dec tone
Lack of sitting at 7mon= dec tone
Hand dominance <18mon= contralateral motor abnormality

Vary pitch by 4mon
Lack of babble by 6mon
No word/gesture by 15mon
No pointing by 18mon
Less than 50% intelligible speech at 24mon
62
Q

All children w/ speech delay need ? tests

When do Well Child Exams take place

BP is not a standard part of VS until ? age and how is it calculated

A

Ear exam
Hearing eval w/ tympanometry and audiometry
Auditory Brain Stem Response- r/o peripheral loss

Day 3-5
Week 2
Mon 2 4 6 9 12 15 18 24 30, then annual

After 3y/o
SBP= 80 + Age x 2
DBP= 2/3 of SBP

63
Q

How is newborn metabolic screening conducted

When are anemia screenings performed

How much lead accumulation can cause irreversible developmental/behavior abnormalities

A

Hgb electrophresis

12mon- healthy
4mon- high risk

5-10ug/dL; screen at 12mon
Screening questions from 6mon-6yrs

64
Q

When do TB screenings begin

What groups are at high risk for TB

When does cholesterol screening begin

A

12mon

Close contact
Heath care workers
Foreign born

Non fasting 9-11y/o and 17-21y/o
Overweight/Obese- fasting
Parents >240= start at 2y/o

65
Q

What are the accepted cholesterol limits in kids

A

Total:
Borderline: <170; High: >200

LDL:
Acceptable: <110
Border: 110-129
High: >130

HDL should be >40

66
Q

Define Active Immunity

Define Passive Immunity

Define Primary Prophylaxis

Define Secondary Prophylaxis

A

Immunity from vaccine/toxoid

Maternal Ab transfer/administration of Abs

Prevent infection before first occurrence

Prevent recurrence after first infective episode

67
Q

How are premature infants immunized

What is the exception to this schedule

When is DTaP given

A

Regardless of birth weight, same chronological age/schedule

Hep B vaccine if <2000g w/ HBsAg negative mother- give first dose at 1mon

5 doses at 2, 4, 6, 15, 48mon
One adult dose at 12

68
Q

When is MCV4 Meningococcal given

When is HPV vaccine given

What are the time frames Rotavirus must be given

A

11-12y/o or prior to college

9-22y/o
Two doses if completed by 15y/o

First dose- 15wks old, final dose NLT 8mon

69
Q

What two vaccinations have cautionary warnings d/t egg allergy

Risks of tobacco smoke

How long should rear facing car seats be used and how long should kids ride in back seat

A

Influenza, Yellow Fever

LBW
SIDS
Respiratory illness- asthma
Otitis media

2y/o;
Back seat until 13y/o

70
Q

What is the sequence of teeth eruptsion

What labs are ordered if delayed tooth eruption is present

Epidemiology of SIDS

A

Deciduous: lower central incisors to upper central incisors to lateral incisors;
Permanent 6-12y/o w/ 3rd molars by 18y/o

TSH, Ca for Hypothyroid/Hypopituitary, Rickets

MCC of death 1-12mon
3rd MCC mortality in USA

71
Q

Define SIDS

? technique may be beneficial in reducing/preventing SIDS

When do cases of plagiocephaly need to be referred

A

Unexpected death <1y/o unexplained by autopsy/CSI and review of clinical history

Pacifiers for first 12mon

No resolution x 4-6mon

72
Q

What are the defining criteria for FTT

What are the three classifications of FTT

A

Weight <3rd percentile
Weight decreases x two major percentiles
Weight <80% of median weight for height

Type 1: Wasting; deficient weight gain d/t malnutrition

Type 2: Shunting; deficient linear growth w/ head circumference spared d/t malnutrition x months

Type 3: Symmetric; proportional loss weight, height and circumference d/t long standing malnutrition, chromosome abnormalities or infection/exposure

73
Q

Majority of FTT cases are d/t ?

How is FTT Tx

Why is Refeeding Syndrome deadly

A

Non-organic: Ignorance Abuse Neglect

Inc calories/protein x >1.5x

Starvation forces nutrient storage for homeostasis
Rapid feeding- loss of fluid/E+; fluid retention, Hypo-Phos/Mg/K/Ca

74
Q

Autosomal dominant congenital malformations

Autosomal recessive congenital malformations

X-linked congenital malformations

A
Huntingtons
Neurofibromatosis
Marfans
Achondroplasia
Polycystic kidney

CF CAH PKU SS

Fragile X- excessive gene base repeats
Muscular dystrophy
Hemophilia A
Color blindness
G6PD deficiency
75
Q

The incidence of chromosomal abnormalities decreases w/ ?

What do all Pts w/ Downs need to have ordered

What are the three forms of Trisomy 21

A

Gestational age

Chromsomal analysis;
If +translocation= parental analysis

MC- maternal non-disjunction
Translocation- part of #21 is stuck on another chromosome prior to replication
Mosaicism- rarest; phenotypical normal Pt

76
Q

What will be seen on PE of Down Syndrome

What are the face characteristics

What are the extremity characteristics

A

Generalized hypotonia- dec Moro reflex
Small head

Flat bridge d/t midface hypoplasia
Up slanting fissures
Macroglossia
Epicanthal folds
Dysplastic pinna

Single palmar crease
Shortened mid-5th phalanx
Wide first toe interspace

77
Q

All Down Syndrome Pts will have ?, two-thirds have ? and half will have ?

What type of hearing loss will majority have

What eye defects will they have

A

All- developmental delay
2/3: polycythemia
Half- cardiac anomalies

SNHL

Cataracts
Refractive error
Ectopic lens
Brushfield spots
Strabismus
78
Q

? type of cardiac anomalies are seen w/ Downs?

? GI complication/x-ray finding in Down Syndrome needs immediate surgical Tx

What is the routine health care check list for all Down Syndrome Pts

A

Enocardial cushion defects: ASD/VSD

Duodenal atresia; seen as “double-bubble” sign

Audio screen q3mon until 3y/o, then annual
Cards for Echo
Optho by 6mon then annual
Annual TSH/CBC, Celiac screen

79
Q

? is the most preventable cause of developmental delay/intellectual disability

What are the classic facial features

What hand feature is seen

A

Fetal Alcohol Spectrum D/o;
3rd MCC developmental delay

Short palpebral fissures
Smooth philtrum
Thin upper lip

Clinodactyly- hockey stick crease

80
Q

? type of motor dysfunction may be seen on ASQs for kids w/ FAS

How much ingestion puts fetus at risk for developing this

What developmental/Neuro problems seen win Fragile X Syndrome

A

Fine motor delay w/ coordination

> 7/wk or >3 drinks per period

Sterotypy (hand flap) Hyperarousal Anxiety Mood lability Epilepsy

81
Q

What physical attributes will be seen in Peds w/ Fragile X Syndrome

How is this definitively Dx

What referral may be needed

A

Joint laxity
Oblong face
Hypotonia
Macro-orchidism

DNA amplification w/ direct analysis

SpEd Neuro (seizure) Autism Genetics

82
Q

Define 45XO

Majority of defects arise from ? side

What may be seen shortly after birth if infant survives to delivery

A

Turner Syndrome d/t no/abnormal X

2/3 of X are maternal

Extremity edema

83
Q

What type of mental development is seen w/ Turner Syndrome

What CV issues are usually seen

What endocrine d/os are seen

A

Poor visual-spacial skills
Superior verbal skills

Coarctation
Early onset HTN
Bicuspid aorta

Hypothyroidism
Osteoporosis
DMT1

84
Q

How is Turner’s Dx

What Dx method is not recommended

How are these Pts Tx/managed

A

Direct karytotyping

Barr body analysis d/t high number of mosaics

Annual TSH, Chem-7, UA
Cards- Echo, MRI, EKG
Endo- GH initiation

85
Q

Define Klinefelter Syndrome

What issue can present

How is this screened, Dx and what would be seen on lab results

How are these Pts Tx and what are they at risk for

A

47XXY: phenotypically normal prior to puberty

Result of testosterone deficiency:
Irregular features
Violent tendencies
Severe MR

Screen: Barr body
Dx: direct karytopying
Inc LH/FSH w/ low T

T replacement
16-30x inc risk for breast Ca

86
Q

What type of genetic defect leads to Marfans

What three systems are affected

Crying from an infant can signal ? possible issues

A

Fibrillin 1 gene on Chrom #15

Ortho: arachnodactyly
CV: AV insufficiency/dissection
Ocular: dislocation

Pain Distress Fatigue Hunger
Pain > Hunger= higher pitch/intensity

87
Q

What body ratios are off in Pts w/ Marfans

What is the correlation to crying if infant is preterm

When is the diurnal variation more common and how loud can it be

A

Reduce upper/lower body
Inc arm span

Little before 40wks old
More than term infant at corrected 6wks

Late afternoon/evening; 80dB

88
Q

What findings suggest a crying infant has colic

What is the Wessel’s Rule of 3 for Colic

When does the Dx of exclusion begin to risk maternal health

A

Paroxysmal crying w/ grimace, leg flexion and flatus

Starting at 3wks:
Crying >3hrs/day
Crying 3d/wk
Crying longer than 3wks
Resolves around 3mon old

Inc PPD risk if crying episodes >20min

89
Q

? is the MC reported behavior problem in kids 2-3y/o

When does this MC become an abnormal

How can these be prevented

A

Temper tantrum

Past 4y/o
Injury to self/others
Lasting >15min
>5/day
Negative mood swings w/ tantrum

Parental education at 12-18mon

90
Q

What is the goal of therapy for Peds w/ special needs

What stages do parents go through after a Dx for special needs

Possible environmental RFs for Autism

A

Maximize potential for adult function

Kubler-Ross stages of grief

Infections- Rubella, CMV
Maternal obesity
Advanced parent age
Premature
Short pregnancy interval
91
Q

What screening form is used for Autism Dx and when

Define Cerebral Palsy

What are 3 potential RFs

A

M-CHAT-R at 18-24mon
Two predictive- hearing concern, finger movement near eye, noise sensitivity or,
Three total

Intrauterine infection
Multiple pregnancies
Infertility Tx

Athetosis, Chorea

92
Q

What are the 6 classifications of Cerebral Palsy

A

Mixed- catch all for Pts that don’t fit other patterns

Ataxic- cerebellar injury causing abnormal posture/coordination

Dyskinetic- involuntary, repetitive movements

Dystonic- rare; stiff/dec movements

Spastic- MAJORITY; pyramidal tract injury to upper neurons w/ two: abnormal movement, inc tone, pathologic reflexes

Choreoathetotic- hyperkinesia, hypotonia; rare now that bilirubin is Tx

93
Q

How is ADHD Dx

What genetic d/os are associated w/ this condition

A

16y/o or :
5 Sxs of inattention or hyperactive impulsitivity
x 6mon in two environments

Fragile X
22a11.2 deletion syndrome
NF-1

94
Q

What is at the core of all ADHD Tx

What meds are used first line

What SNRI can be used

What A-agonists can be used

A

Behavior management

Methylphenidate
Amphetamine

Atomoxetine

Clonidine, Guanfacine

95
Q

? are the two behavior rating checklists for ADHD

Define Oppositional Defiant D/o

Define Conduct D/o

A

Conners, Vanderbilt

Moody, defiant, vindictive behavior

Pattern of behavior where basic rights/norms are violated:
Aggression Destruction Deceit Violation

96
Q

What screening tool is used for OCD

What is the mnemonic for interviewing adolescent Pts

A

Vanderbilt

HEADDSS:
Home/Friends
Education
Alcohol
Drugs
Diet
Sex
Suicide/Depression
97
Q

Average age for female puberty is ? but preccocious puberty is defined as ?

Tanner stages associated w/ TAPuPMe

Completion of Tanner stages takes ? amount of time for male and female

A

11y/o;
6y/o in AfAm; 7 y/o in Caucasian

Thelarche: Tanner 2
Ad/Pub: Tanner 2
Peak: one year after thelarche, tanner 3-4

Female: 4-5yrs
Male: 2.5-5yrs

98
Q

Once female starts menarche, ? much expected height growth is expected remaining

A

a