A&P 1: Special Senses Flashcards
What are the two classes of sensory modalities?
General senses
Special senses
General senses include what two senses?
Somatic Senses
Visceral Senses
What is the first step in the process of sensation?
Activation of sensory receptors by stimulus
Sensory receptors comprise either _____ or _____
Specialized cells
Dendrites of sensory neuron
4 events required for sensation
Stimulation
Transduction
Generation
Integration
For stimulation of the sensory receptor to occur, the stimulus must occur within _______?
Receptive field of the receptor
Body region where stimulation causes a response
Sensory receptors transduces energy in a stimulus into a _______
Graded potential
Sensory receptors can be placed into 3 classifications
Microscopic appearance
Origin of stimuli
Type of stimulus
3 classifications by microscopic appearance
Free nerve endings
Encapsulated nerve endings
Separated cells
Define Free Nerve Endings
Bare dendrites with no structural specialization
Define Encapsulated Nerve Endings
Dendrites enclosed in connective tissue capsule
Define Separate Cells
Specialized cells that synapse with first order sensory neurons
What do separate cells detect?
Hearing/equilibrium hair cells
Photo receptors
Gustatory receptors
Sensory receptors produce what two types of graded potentials?
Generator potential
Receptor potential
What produces Generator Potentials?
Free Nerve endings
Encapsulated nerve endings
Receptive part of olfactory receptors
A cold-sensitive receptor is an example of what type of sensory receptor?
Free Nerve Ending
Lamellated corpuscle is an example of what type of sensory receptor?
Encapsulated nerve ending
Of the two types of graded potentials made by sensory receptors, which one is not a first-order neuron?
Receptor potential
Define Adaptation
Decrease in generator/receptor potential amplitude to a prolonged stimulus
3 examples of rapidly adapting receptors
Touch
Pressure
Smell
3 examples of slow adapting receptors?
Pain
Proprioception
Chemical
Define somatic sensations
Arise from stimulation of sensory receptors in skin/subcutaneous layer in mucus membrane, muscles, tendons, joints and inner ear
Define Cutaneous sensations
Somatic sensations that arise from stimulating surface of skin
Free nerve endings of tactile sensations sense what stimuli?
Encapsulated sense what?
Itch and tickle
Touch, pressure, vibration
Define Touch Sensation
Stimulation of tactile receptors in skin or subcutaneous layer
What are the 2 types of touch?
Crude- Something is contacting but can’t determine location, shape, size and texture
Fine- specific information is provided, location, shape, size, texture
Define Pressure
Sustained sensation that is felt over larger area than touch due to deformation of deeper tissues
Define Vibration
Rapid and repetitive sensory signals from tactile receptors
What are the 2 types of receptors for vibration?
Meissner corpuslces- low-frequency vibrations
Pacinian corpuscles- higher frequency vibrations
Define itch
Stimulation of free nerve endings by certain chemiclas, possible local inflammatory response
Define tickle
Sensations arising from free nerve endings and lamellated corpuscles
Thermoreceptors are unspecialized free nerve endings that respond to changes primarily within the ____ range
Innocuous
Where are thermal sensation receptors?
Skin
Cornea
Tongue
Bladder
Pain receptors are found in every tissue in the body except?
Brain
Tissue irritation/injury release what 3 chemicals that stimulate nociceptors?
Kinins
Prostaglandins
K+ ions
Define Kinins
Polypeptides that cause vasodilation, increase vessel permeability, and chemotactic agents for phagocytes
Define Prostaglandins
Lipids that intensify effects of histamine, kinin and stimulate emigration of phagocytes through capillary walls
Types of pain are differentiated based on?
Types of nerve fibers that propagate impulses
Where in the body the type of pain can occur
Fast pain fibers are AKA?
Acute
Sharp
Pricking
Pain by location of receptors can be divided into 3 types
Superficial
Deep
Visceral
When does referred pain usually occur?
Nerve fibers from HIGH sensory input and fibers from LOW input converge on same levels of the spinal cord
What are the 3 types of proprioceptors
Muscle spindles
Tendon organs
Joint kinesthetic receptors
Define Muscle spindles
Proprioceptors in skeletal muscles that participate in stretch reflexes
Define Tendon Organs
Located at junction of tendon and muscle, provide info about changes in muscle force
What is the purpose of Tendon Organs?
Protect tendons and muscles from damage from tension
Define Joint Kinesthetic Receptor
Provide info about parameters associated with movement of synovial joints
What are the parameters of joint kinesthetic receptors?
Pressure
Velocity changes
Tension
Where are joint kinesthetic receptors located?
Around articular capsule of synovial joint
Olfaction produces a ____
Gustation produces a _____
O= generator potential G= receptor potential
Olfactory epithelium consists of what 3 kinds of cells?
Olfactory receptors
Supporting cells
Basal stem cells
Olfactory supporting cells are AKA ?
Sustentacular cells
Olfactory receptors are what kind of neurons?
Bipolar first-order neurons
Each olfactory receptor has what 3 parts?
Axon ending in olfactory bulb
Knob shaped dendrite
Cilia projecting from dendrite
What are the olfactory hairs?
Cilia projecting from dendrites of olfactory receptors
What is the site of olfactory transduction?
Olfactory hairs
How are olfactory responses initiated?
Chemical stimulation of odorant molecule that produces a generator potential
What are the olfactory supporting cells?
Columnar cells of mucous membrane lining the nose
Supporting cells in the nose provide what 3 things?
Physical support
Nourishment
Electrical insulation
What is unique about the basal stem cells?
Undergo continuous division producing new olfactory receptors since they only life for a month
What are Olfactory Glands
What are they AKA?
Produce mucus
Bowman’s glands
What is the function of the Olfactory Glands?
Moisten epithelium
Dissolve ordorants
What CN innervates supporting cells and olfactory glands?
CN7
Where do olfactory nerves terminate?
Olfactory bulbs- paired gray matter masses
Site of end of first order and synapse with second order neurons
What is formed when olfactory bulb axons extend posteriorly?
Olfactory tract
Where is the primary olfactory area?
Lateral olfactory area
Site of conscious smell beginning
What is unique about the olfactory pathway?
Only sensation that reaches cerebral cortex without synapsing with thalamus first
How do olfactory senses trigger emotion/memory linked responses to odors?
Olfactory tract projects to limbic system and hypothalamus
Where do second order olfactory neurons project to?
Olfactory bulb to brain to form a sensory map
What kind of deficiency is the cause of many cases of anosmia?
Zinc- growth factor for receptors of chemical senses
Taste buds are located in what 4 areas?
Tongue
Soft palate
Pharynx
Epiglottis
Taste buds consist of what 3 types of cells?
Gustatory receptor cell
Supporting cell
Basal cell
Where is a taste pore?
Apex of taste bud
Define gustatory hair
Long, single microvillus projecting through taste pore
What is the sequence of cellu progression for gustatory cells?
Basal->supporting->gustatory
Gustatory live for 10 days
What is the site of taste transduction?
Gustatory hairs
Sweet tastes are associated with what?
Why?
Safe food
Requirement for carbs
What is the conventional receptor location for sweets?
Tip of tongue
Sour tastes are associated with what?
Spoiled foods
What is the conventional receptor location of sours?
Back sides of tongue
Bitter tastes are associated with what?
Poisonous foods
Where is the conventional receptor location of bitters?
Back middle of tongue
Salty tastes are associated with what?
Sodium Chloride
Where is the conventional receptor location of salty?
Sides of tongue
Umami is the taste of what?
Amino acids
Meaty, savory, broth like
Taste buds occur in elevations of the tongue called what?
Papillae
What are the 3 types of papillae?
Vallate
Fungiform
Foliate- lost during childhood
Define filiform papillae
Papillae with tactile receptors to distinguish food textures but can’t taste
What taste has the lowest threshold?
Bitter
Sour slightly higher
Define flavor
Combination of taste plus odor (retronasal olfaction)
Define retronasal olfaction
Volatile food chemicals carried into nasal cavity from behind
Olfactory epithelium can act in what two types of olfaction?
Retronasal
Orthonasal
What sense pathway doesn’t have an axon?
What are they called instead?
Gustatory
Graded potential produced called receptor potentials
What 3 CNs make up the gustatory pathway?
CN 7- anterior 2/3 of tongue
CN 9- posterior 1/3 of tongue
CN 10- throat and epiglottis
Where is the gustatory nucleus?
Medulla obonglata
Where do gustatory axons project to from the medulla?
Limbic
Hypothalamus
Thalamus
Where is the primary gustatory area?
Parietal lobe of cerebral cortex to give conscious perception of taste
3 functions of palpebrae
Protect from light
Protect from objects
Spread lubrication
Define palpebral fissue
Space between upper and lower eyelids
Define Commissures
Angles of the palpebral fissure
Define lacrimal caruncle
Medial commissure containing sebaceous and sudoriferous glands
What are the structures of the eyelid from superficial to deep?
Epidermis Dermis Subcutaneous tissue Fibers of orbicularis oculi muscle Tarsal plate Tarsal glands Conjunctiva
Define Tarsal Plate
Fold of CT that gives form and support to eyelids
Define Tarsal Glands
Secretes fluid to keep eyelids from adhering to each other
Tarsal glands are AKA ?
Meibomian glands
Define Palpebral conjunctiva
Define Bulbar conjunctiva
P= lines inner aspect of eyelid B= on anterior surface of eyeball, covers sclera but not cornea
Define lacrimal apparatus
Group of structures that produce and drain tears
What are the 3 parts of lacrimal fluid
Salts
Mucus
Lysozyme
How is lacrimal fluid drained into the eye?
Excretory lacrimal duct on surface of conjunctiva of upper lid to pass medially over eye ball
What CN innervate the extrinsic eye muscles?
CN 3 4 6
Define cardinal directions of gaze?
6 of the 8 eye movements that are associated with a single extrinsic muscle
Define Strabismus
Imbalance of extrinsic eye muscles so lines of vision are not parallel
Deviant eye input disregarded and becomes functionally blind
What is the layman term for Strabisus?
Lazy eye
Define Nystagmus
Rapid involuntary movement of eyeballs
Sign, not a disease
What type of nystagmus is more frequent?
Horizontal
Define Vestibular Nystagmus
Eye movements that occur during/after rotational motion
What is horizontal gaze nystagmus useful?
Police use it to test field sobriety
What are the 3 layers of the eye?
Fibrous tunic
Vascular tunic
Retina
Define Fibrous Tunic
What are it’s two parts?
Superficial coat of eye that is avascular
Cornea and Sclera
Define Cornea
Transparent coat that covers iris
Curved so it can focus light
Sclera covers entire eye except for where?
Cornea
What is the function of the sclera?
Eye shape/rigidity
Define Vascular Tunic
What are the 3 parts?
Middle layer of eye
Choroid, ciliary body, iris
What are the functions of the choroid?
Vascularized to provide nutrients to posterior surface of sclera
What are the two parts of the Ciliary body?
Ciliary process
Ciliary muscle
Define Ciliary processes
Contain blood capillaries that secrete aqueous humor
Define Ciliary Muscle
Alters shape of lens
When the lens more spherical, what type of vision is allowed?
Contracted Ciliary, reduced tension of suspensory ligaments, more spherical shape for closer vision
Where does the iris connect to the eye?
Ciliary processes
What does the Parasympathetic and Sympathetic systems alter in the eye?
Parasymp- sphincter pupillae (circular muscle) to decrease pupil size
Symp- dilator pupillae (radial muscle) increases puil size
What is the inner coat of the eye?
Retina
What does the retina mark the beginning of?
Visual pathway
What is the only place in the body where blood vessels can be directly viewed and examined?
Retina
What is the optic disc?
Site where optic nerve exits eyeball
What two structures are adjacent to the optic disc?
Central retinal artery
Central retinal vein
What is the function of pigmented layer of the eye?
Absorbs stray light to prevent reflection/scattering
What is the neural layer of the retina?
Outgrowth of brain
What are the 3 layers of the neural layer?
Photoreceptor
Bipolar
Ganglion
What are the 2 zones of the neural layer?
Outter/inner synaptic layer
What are the two types of photoreceptors found in the neural layer?
Rods- low threshold, only see shades of gray
Cone- higher threshold, color vision
Define Macula Lutea
Exact center of visual axis of eye in posterior retina
What is the small depression in the center of the macula lutea and what does it contain?
Central fovea, only cones
What part of the eye has the highest visual acuity/resolution?
Fovea centralis
What is the blind spot of the eye?
Optic disc, no rods or cones
What does age-related macular disease effect in the eye?
Degeneration of retina and pigmented layer within macula lutea
What kind of vision do age related macular disease PTs have?
Retain peripheral
Lose straight ahead sight
What are the two types of age-related macular degeneration?
Dry- central layer fades due to pigmented layer atrophy/degeneration, no treatment
Wet- new blood vessels form and leak plasma/blood under retina, treated with laser surgery
Where is the lens located?
Behind pupil and iris
What are the proteins of the lens called?
Crystallins
What is the variably refractive medium of the eye?
Lens
Define cataract
Loss of lens transparency
How are cataracts repaired?
Removal of lens and implantation of new artificial lens
What divides the eye into its two cavities?
Lens
What are the two chambers of the anterior chamber?
Anterior- between cornea and iris
Posterior- behind iris, front of lens
What type of liquid is in the chambers of the anterior cavity?
Aqueous humor
Which fluid makes up the majority of intraocular pressure?
Aqueous humor
How is aqueous humor made?
Filtration of blood by capillaries of ciliary processes
Where does aqueous humor flow within the eye?
Between iris and lens, through pupil, into anterior chamber, drains to scleral venous sinus at junction of sclera and cornea, returns to blood
How often is aqueous humor replaced?
90 min
What is the Scleral venous sinus AKA?
Canal of Schlemm
Define Glaucoma
High intraocular pressure
What type of damage does glaucoma cause on the eye?
Optic nerve and retina damage leading to blindness
What causes glaucoma?
Impaired drainage of aqueous humor
Define the ocular angle
Canal of Schlemm at vertex of the angle formed by intersection of cornea and iris
What are the two types of glaucoma?
Closed- posterior chamber pushes iris forward, closing ocular angle, prevents drainage of aqueous humor
Open- abnormality of trabecular meshwork of Schlemm cana impede outflow of aqueous humor
How is glaucoma treated?
Cholinergic agonists- constrict pupil, contract ciliary muscles, decreases pressure
How does glaucoma treatment work in closed or open angle glaucoma?
Closed- pupil constriction lowers intraocular pressure by pulling iris away from Schlemm to open angle
Open- ciliary muscle contraction stretches trabecular meshwork to open tubules
What is the larger chamber of the eye?
Vitreous chamber
What part of the eye holds retina against choroid?
Vitreous body
What part of the eye is phagocytic and provides unobstructed vision?
Vitreous body
What are the 3 parts of the vitreous body jelly?
Water
Hyaluronic acid
Collagen
Where does the vitreous body attach to the retina?
What is this junction important?
Behind ora serrata at the optic disc
Retinal tears/detachment
Define Ora Serrata
What does it mark?
Junction between retina and ciliary body
Transition from non-photosensitive area of retina to photosensitive region
Where does the vitreous body attach to the Ora Serrata?
Anteriorly behind ora serrata
Define blepharitis
Inflammation of eyelid
Diabetic retinopathy is degeneration from what type of diabetes?
Diabetes mellitus
Define Exotropia
Outward turning of eyes
Define Keratitis
Inflammation/infection of cornea
Define miosis
Constriction of pupil
Define Mydriasis
Dilation of pupil
Define Ptosis
Falling/dropping eye lid
Define Scotoma
Reduced/lost vision in visual field
Define Tonomieter
Measures intraocular pressure
Define Trachoma
Serious form of conunctivitis
Greatest single cause of blindness
Define refraction
Light passing through transparent substance and passes into second transparent substance with a different density
What causes refraction?
Light hitting and bending at different times and being refracted
What type of lens causes convergence?
What type of lens causes divergence?
Convex
Concave
How are images received on the retina?
Upside down
Left to right reversal
Light rays reflect from objects are seen as parallel if they are at least ___ ft from the viewer
Why is this?
20ft
Ciliary muscle is relaxed, lens if flat
What happen if light rays are received from objects closer than 20ft?
Not parallel
Lens must be thicker to focus
Define accommodation
Ciliary muscle contracts, reduces tension on ligaments, lens becomes more spherical
Increased curvature for near vision
Without tension from suspensory ligaments, lens assumes what shape?
Convex
What happens to make the lens less convex?
Ciliary muscles relax
Choroid is spring like pulls lens through ligaments
How does the lens become thicker?
Ciliary muscle contracts
Choroid stretched, releasing tension on lens
Define Near Point of Vision
Minimum distance from eye that an object can be clearly focused
Define Presbyopia
Loss of elasticity of the lens due to age
People need glasses
Glasses need bifocals
A normal eye is termed as _____
Emmetropic
What are 3 refraction abnormalities?
Myopia- nearsightedness
Hyperopia- farsightedness
Astigmaism- irregular cornea curvature
What causes myopia?
Eye is too long relative for focusing power of the cornea/lens
What type of image is formed with myopia?
How is this corrected?
In front of retina due to eleongated eye/thick lens
Concave lens
How does hyperopia occur?
Eye is too short relative to focusing power of cornea/lens
What type of image is produced with hyperopia?
How is it corrected?
Focused behind retina due to shoretened eye/thin lens
Convex lens
What causes Astigmatism
Irregular curvature of cornea/lens
What type of image is produces with astigmatism?
How is this corrected?
Blurred/distorted/out of focus
Lens that rotate axis of lens
Define binocular vision
What does this provide?
Both eyes focus on only one set of objects
Depth and 3D
How does binocular vision occur?
Light rays from object stike corresponding points of two retinas and each eye sees same image from different angles
Define stereoscopic vision
Brain fusing binocular vision input into two different images from each eye
“seeing solid”
Define Convergence
Medial movement of eyes so both are toward object being viewed
Where are cones more numerous?
Where are rods more numerous?
Cones= central fovea Rods= ring around foveal pit
What is the cone peak?
Central fovea, area with the most cones
What part of the rod/cone is the area that light energy is transduced?
Outer segment
What does the outer segment of the cone look like?
What does the tip of each rod look like?
Cone- folds, pleated fabric
Rods= stacked discs
When does rod and cone phagocytosis occur?
Rod- exposed to light
Cone- darkness
What are the 3 structures contained within the inner segment of rods and cones?
Nucleus
Golgi app.
Mitochondria
What end of the rod or cone expands in the synaptic terminal?
Proximal
Define photopigments
Colored, integral proteins in membrane of outer segment of rods/cones that undergo structural changes when light is absorbed
What are the two parts of photopigments?
Retinal- derived from Vit A
Opsin- glycoprotein
What is the photopigment in rods?
What does it absorb?
Rhodopsin
Blue and green
What aer the 3 photopigments in cones?
Photopsin I- yellow
Photopsin II- green
Photopsin III- blue-violet
What portion of photopigment is different in each of the different photopigments?
Opsin portion
What part of the photopigment is key in transducing light?
Retinal
What happens to retinal in darkness?
Cis-retinal
What happens when cis-retinal abosrobs light photons?
Trans-retinal
Define isomerization
Cis to trans conversion
Define regeneration
Light-induced insomerization of cis-trans causing rhodopsin to decompose
Photopigments need to be re-made
Cis-retinal can rebind to opsin forming functional photopigment
What is the normal color of rhodpsin?
Red
Define Bleaching of Photopigment
Presence of light causes cis-retinal converted to trans-retinal
Opsin is without retinal is colorless
What enzyme isomerases trans to cis retinal?
Retinal isomerase
What is causing the painful bright light when someone goes from dark to light?
Photopigments being broken down
Define nyctalopia
What causes it
Inability to see well in low light levels
Low Vit A
How many rods synapse with a bipolar cell?
How many rods synapse with a bipolar cell?
Rod- 6-600
Cone- 1
Convergence of many rods into a single biopolar cells causes _____ light sensitivity and a _____ in image acuity
Increase
Decrease
Cone vision is ____ sensitive and ____ acuity
Less
Higher
When does the optic nerve stop and the optic tract begin?
Passage through optic chiasm
Where does the otpic tract terminate?
Lateral geniculate nucleus of thalamus
Thalamus forms optic radiation and projects them to where?
Primary visual area in occipital lobes of cerebral cortex
What is the visual field?
What is the field of binocular vision?
VF- everything seen by that eye
FoB- where two visual fields overlap
Visual field of each eye is divided into what two regions?
Nasal (central half)
Temporal (peripheral half)
How is light received from each part of the visual field?
Nasal half light fall on temporal half of retina
Light from temporal half fall on nasal half of retina
Which optic field does not cross over to the opposite half of the brain?
Temporal
What part of the eye govern constriction of pupils and coordinate head and eye movements?
Axon collaterals of retinal ganglion
How is circadian rhythms formed?
Collaterals go to suprachiasmatic nucleus of hypothalamus
Define Optic Radiations
Projections of axons from thalamus to primary visual area of cortex on the same side
Define Amblyopia
Loss of visual in a normal eye caused by no/poor transmission of visual stimuli to optic nerve and brain
“Lazy Brain”
3 systems within the cerebral cortex process and interpret visual signals based on what 3 input?
Shape
Color
Movement/location/spatial
What are the 3 regions of the ear?
External- collects and funnels sounds
Middle- conveys vibrations to oval window
Internal- receptors for hearing and equilibrium
What are the 3 parts of the external ear?
Auricle
External auditory canal
Eardrum
What is the helix of the ear?
What is the inferior portion called?
Outer rim
Lobule
Define Tragus?
What structure is opposite to it?
Pointed eminence projecting back over meatus
Antitragus
What structures are near the region of the outer ear?
Mastoid process posterior to lobule
Superficial temporal artery anterior to tragus
How/where does the incus articulate?
Laterally w/ malleus
Medially w/ stapes
Which ossicles produce bulges on the TM and can be viewed?
Handle/lateral process of malleus
Long limb of incus
What are the 2 skeletal muscles that attach to ossicles?
Tensor tympani muscle
Stapedius muscle
Where does the Tensor Tympani originate and insert with what CN?
Wall of auditory tube
Inserts on handle of malleus
CN5
What is the function of the Tensor Tympani muscle
Limits movement
Increases tension on eardrum to prevent damage from loud noises
Where does the Stapedius muscle origninate, insert and get innervated by?
Poasterior wall of ear cavity
Stapes
CN7
What is the function of the Stapedius muscle?
Dampens large vibrations of stapes due to lout noises
What is the smallest skeletal muscle in the huan body?
Stapedius muscle
What is the visual appearance of a normal TM?
Pearly gray and translucent
What is the cone of light?
What is it AKA?
Reflection of otoscope illuminator
Light reflex- radiates anterioinferiorly in healthy ear
The Eustacian Tube is AKA?
Auditory Tube
Pharyngotympanic tube
What does the Eustacian tube connect?
Middle Ear with Nasopharynx
What 2 events opens the eustacian tube?
Yawn
Swallow
Opening the eustacian tube allows pressure to equalize where and prevents what?
Middle ear and atmosphere
Pain and vertigo
Inner ear is AKA ? with waht 2 divisions
Labyrinth
Bony and Membranous
What are the 3 areas of the bony labyrinth?
Semicircular canas
Vestibule
Cochlea
What/where is the membranous labyrinth?
Sacs and tubes in the bony labirynth
Define Perilymph and its location
Similar to CSF surrounding membranous labyrinth
Where is Endolyph found?
What does it have a high level of?
Membranous lbyrinth
K+
Define Vestibule
Oval center of bony labirynth and part of membranous in the center
What two structures make the vestibule?
Utricle
Saccule
Where is the oval window?
Vestibule
AKA Vestibular window
What appearance do the semicircular canals have?
Right angles to each other
Anterior/Posterior- vertical orientation
Lateral- horizontal
What structure is at the end of each semicircular canal?
AMpulla
Parts of the membranous labyrinth are in the semicircular canals and are called ? and connect to ?
Semicircular ducts
Connect to urticle
Define Menieres Disease
Increased endolymph
Fluctuating hearing loss
Tinnitus
Whirling vertigo
The vestibular branch of CN8 is made of what 3 nerves?
Ultricular
Saccular
Ampullary
Where are CN8 sensory neuron cell bodies located?
Where are the motor neurons located?
Vestibular ganglia
Pons- project to semicircular, saccule and utricle
What is the center of the chochlea called?
Modiolus
Cochles has a Y-shaped partition that forms what 3 channels?
S. Media- AKA cohclear duct
S. Vestibuli- ends @ oval window
S. Tympani- ends @ round window
S. Vestibuli and S. Tympani are both filled with what fluid?
Perilymph
S. Vestibuli and S. Tympani are separated except for where?
Helicotrema
“hole in the spiral”
Scala media is a continuation of ?
Membranous Labyrinth
What two membranes contain perilymph within the respective scalae?
Vestibular Mem- S. Vestibuli
Basilar Mem- S. Tympani
Spiral organ/Organ of Corti is on what membrane?
Basilar within cochlear duct
Where are the hair cells that are the receptors for hearing located?
Cochlea
Hair cells in the spiral organ are in what 2 groups?
Inner- single row
Outer- three rows
What do the inner and outer hair cells synpase with?
1st order sensory neurons
Motor neurons from Cochlear Branch of CN8
Where/what are the only neurons that have a myelin sheath surround the cell body?
Afferent fibers from cochlea
Cell bodies of sensory neurons are located in the ____
Cell bodies of motor neurons are located in the _____
Spiral ganglion
Pons
Which membrane projects over and contact the cochlea hair cells?
Tectorial
Define sound
Alternating High and Low pressure regions of a medium
Frequency = \_\_\_\_\_ Amplitude = \_\_\_\_\_
Pitch
Volume= intensity
Sound is _____ vibrations
sympathetic
What is the most acute and audible frequency ranges?
Acute= 500-5000 Herts/cps Audi= 20-20K Hz
Amplitude threshold is defined as ?
0 dB at 1000 Hz
When healthy ear can detect sound from silence
Normal conversation = _dB
OSHA hearing req @ __dB
Rock concert = _dB
60
90
110
How are shorter sterocilia connected to taller sterocillia?
Tip link protein
What kind of ion channel is associated with tip link proteins?
Mechanically gated ion channel
Steps of hearing
Sterocilia bend towards taller hair
Transduction channels open
Cations enter enolymph and depolarize
Opposite bending closes channel
Axons of the cochlear branch synapse with which neurons?
Cochlear nuclei in medulla oblongata
Neurons that dcussate in medulla and ascend to where?
Lateral lemniscus on opposite side to terminate in inferior colliculus of the midbrain
Axons from the cochlear nuclei that don’t go to the medulla end where?
Superior olivary nucleus in pons
How can we tell the direction of sounds?
Difference in timing of impulses arriving to superior olivary nuclei
Where are impulses sent to after the inferior colliculus?
Medial geniculate nucleus of the thalamus
Then
Primary auditory area of cerebral cortex
Exceptionally loud noises damages what part of the hearing sequence?
Sterocilia
What are the two types of deafness?
Sensorineural- damage/disease of pathway of CN8
Conduction- impaired mechanisms of external/middle ear
Define Otoacoustic Emissions and their usefulness
Sounds produced by cochlea and are used to test infants for deafness
What are the two types of equilibrium
Static- position against gravity
Dynamic- position against sudden movement
What are the receptor organs for equilibrium?
Vestibular apparatus- includes saccule, utricle and semicircular ducts
Where/what is the macula
Walls of utricle and saccule
Horizontal to utricle
Vertical to saccule
Maculae is made up of what 2 kinds of cells?
Hair- sensory receptors
Supporting- form otolithic membrane
What are the two types of hairs that are in a bundle?
Sterocilia- actually microvilli
Kinocilium- one per bundle, true cilium, longer than longest sterocilia of the bundle
What covers the surface of the otolithic membrane?
Otoliths- calcium carbonate crystals
What causes the otolithic membrane to slide over hair cells?
Head tilts or Acceleration that causes inertia
Maculate respond only to what two types of changes?
Acceleration or Velocity of the head
3 parts that make up Dynamic Equilibrium
3 semicircular ducts
Saccule
Utricle
What is located in the ampullas that are found at the end of each semicircular canal?
Crista Ampullaris
Each Crista Ampullaris contains what 3 things?
Hair cells
Supporting cells
Cupula- gelatinous material
Define Vestibular Nystagmus
Strange eye movements that occur after rotational movements
Equilibrium cell bodies are located where?
Vestibular ganglia
Equilibrium pathway axons comprise what?
Vestibular part of CN8
Most axons of vestibular branch synapse where?
Vestibular nuclei in medulla oblongata
What happens to the equilibrium axons that dont synapse in the medulla?
Enter cerebellum through inferior cerebellar peduncles
How are the cerebellum and vestibular nuclei connected?
Bidirectional pathways
Define Cochlear Implant
Device that translates sounds into electrical signals for brain interpretation
Define Presbycusis
Age related loss of hearing
Define Otalgia
Earache
Define Sensorineural deafness
Impairment of hair cells in cochlea or damage to cochlear branch of CN8
Define Conduction Deafness
Deafness caused by impairment of external/middle ear mechanisms ability to transmit to cochlea
Define Ottitis Media
Middle ear infection
Define Tympanotomy
Tube placed into eardrum to drain fluid from middle ear
Define Barotrauma
Damage/pain from pressure changes, usually affecting the middle ear
Define Vertigo
Sensation of spinning, either world or person