Peds Block 2 Flashcards
What are the three categories of fever?
Short duration- localized S/Sxs; dx w/ history and PE
W/out focus- often kids <3y/o; Hx or PE fail to show cause
Unknown origin- Fever >8 days w/out identifiable etiology despite PE, labs or after 1wk of hospitalization
Teething kids usually don’t have a fever higher than ?
What are two main causes of Fever Without Focus/Source?
100.4*
UTI and pneumonia
Serious bacterial infections in neonates/infants are usually due to ? 3 things
What is the most and second most common microbe?
Bacteremia UTI Meningitis
E Coli*, GBS
HSV induced virus is considered if PT is febrile and younger than ?
Peds who appear well but with fever are more likely to have ?
<28days
Virus
Peds under ? w/ fever need to be evaluated by the ER and NOT given ?
Tachypnea= ? Tachycardia= ?
2mon, no antipyretics
> 60breaths pm
180bpm
How do you determine petechiae from other rashes?
All kids <1mon w/ fever w/out focus or source have what follow up step done
Petechiae= no blanching, more concerning
Admitted
CBC, culture, UA/culture, LP, CXR, stool WBC/culture if diarrhea is present
Post-labs: start ampicillin/gentamycin
Kids w/out fever but have toxic signs and are 1-36mon get
Admitted CBC, blood culture, UA/culture, LP (if 1-3mons and irritable*) Stool WBC/culture if diarrhea CXR if Temp >102.1 and WBC >20K Empiric Ceftriaxone or Cefotaxime
What are 2 common bacterial infections in kids?
Acute Otitis Media- bulging, erythematous, and non-mobile TM
Strep Pharyngitis- seen late fall/winter, uncommon <3y/o
Prevent heart complications w/ PCN
What are the female risk factors for UTIs?
What re the risk factors for males?
White, <1yr, 102.2* or higher, Fever 2 days or longer
Uncircumcised, nonblack, temp 102.2 for more than 1 day
What are the two main types of bacteremia?
What are the more common agents?
Source: pneumonia, cellulitis
Occult: +culture in well appearing child
Pneumococcus
H Influenza Type B
Define Fever of Unknown Origin
What’s the difference between FOUO and Fever of Known source?
Fever >100.4 no origin +8 days
Duration
PT >6yo w/ fever is usually due to ? while adolescents w/ fever are more likely due to ?
Preterm infants less than <32wks have not received all maternal ?
Low birth weigh babies can summon ? type of immune reaction?
Respiratory/GU
TB autoimmune IBD lymphoma
IgG- cross placenta during second half of last trimester via active transport
IgM
Define Sepsis and Severe Sepsis
Systemic Inflammation Response Syndrome
Severe= end organ compromise
Temp >101.3
Tachy >2SD for age or,
Hypoxemia <70mm room air
HR >2SD for age or,
HOTN <2SD for age or,
Cap refill >3 sec
Lactic acidosis
Oliguria
AMS
Bacterial meningitis will present with what type of opening pressure?
What type of defect cause kids to be susceptible meningitis?
What two PT populations are more likely to get Strep Pneumo meningitis infections?
High
C5-8 defects w/ spleen issues
Functional asplenic- sickle cell
HIV
How is meningitis transmitted and what PT populations may be more susceptible?
What PT populations are more likely to get N Meningitidis infections?
What 4 serogroups are in the MCV4 vaccine?
Respiratory tract secretion/droplet
Native American/Eskimo
Younger than 5y/o, 15-24y/o
A C W Y X (verify)
B- has own vaccine
A: MC in Africa
B: MC in US
HIB infections more common during what part of life?
N Meningitidis has what 6 serogroups?
N Meningitidis mengingitis presents w/ what 2 S/Sxs?
70% of cases in first 5yrs of life
Peak at 6-9mon
A B C X Y W-135
Pruprua + non blanching
Since ABX are usually started prior to obtaining an LP, what lab results can be elevated for days later?
Traumatic LP taps are less likely to affect Gram stain, culture and glucose but can affect what two results?
Pleocytosis w/ neutrophils
Elevated protein
Red glucose
Leukocytes and Protein
What are 3 meningitis DDx?
Partially treated bacterial meningitis
Encephalitis- changes in mental status, greater risk for seizures, global neuro abnormalties
CNS abscess- focal neuro signs, Dx w/ CT
What ABX for meningitis is recommended for kids outside of neonatal period?
Vancomycin w/ 3rd gen Ceftriaxone
Meropenem- PCN/cephalosporin allergy
L monocytogenes suspected= ampicillin
Imm compromised/gram neg microbe- Cefepime/Meropenem
Three potential complications of meningitis Tx
Which microbe causes the survivors to have sequelaes of deaf, seizure, blind or learning disabilities?
SIADH
Hearing loss
Subdural effusion w/ S Pneumo and H Influenza
Pneumococcal infection
What part of a meningitis presentation indicates a poor prognosis?
Define Encephalitis and the 3 types
Young Long duration Seizure/coma Shock Low/no CSF ImmComp PT
Inflammation of brain parenchyma causing dysfunction (post infxn, chronic degeneration, viral)
What are the most common cause of viral meningoencephalitis?
Picornaviridae- neonate (functionally immcomp) and ImmComp PTs
Arbovirus: arthropod vector, most are zoonotic
What does HSV1 cause?
What does HSV2 cause?
Sporadic encephalitis
Coma/death in 70% of PTs
Neonatal encephalitis vix vertical transmission
What is a common Sx at presentation of acute infectious encephalitis
PTs w/ suspected acute infectious encephalitis get what serological studies?
Seizure
Cat scratch dz- from kitten Lyme dz Epstein-Barr Arbovirus Mycoplasma pneumo