Geriatrics Flashcards
Geriatric clinical approach includes ? three domains that affect ? and ?
What are the 3 main outcome of the assessment for this population
Older PTs care about what 3 results of a prognosis?
Function, Social, Psych
Well being/Quality of life
Prognosis
Patient goals
Functional status
Function Independence Dementia
What are the Activities of Daily Living
What are the instrumental activities of daily living?
Continence Feed Toilet
Transfer Bathe Dress
Drive Meds Telephone Shop
Misenplace Clean Laundry Finance
How is a Functional Evaluation conducted
What is the leading cause of non-fatal injuries and death in older PTs?
How often is this leading cause assessed?
Time to get up from chair
Walk 10ft, return to chair
>30sec= impaired mobility
Falls, Gait
Incidence and Frequency annually
How is gait assessed?
What are the 4 parts of the PTs gait that are assessed?
Can PT rise from chair w/out hands- quad strength
Symmetry Length Height
Width
What are the intrinsic RFs for a fall?
What are the secondary RFs
How can their near/far vision and hearing be tested?
Meds Vision PHOTN
Atrophy Vit D- 800IU/day
Light Footwear Trip hazard Safety
Near- Jaeger
Far- Snellen
Hearing- whisper test
Define the mini cognition test
What is the next step if they fail this test?
How is depression screened for?
3 item recall, clock drawing- 2min
Both norm- dementia unlikely
Mini mental exam- 10min
MOCA, specific- 30min
PHQ 2: two questions, one pos warrants investigation
What are the two questions asked during the PHQ 2 and what are they assessing?
Past 2 wks, felt down, depressed, hopeless- depressive mood
Past 2 wks, felt little interest or pleasure doing things- anhedonia
How does the eye and vision change due to increased age?
These changes lead to ? condition
Why do PTs have difficulties w/ reading in dim light
Lens becomes less flexible, less accommodation
Presbyopia
Dec light to retina
? is the leading cause of vision impairment in the US/world
What are the typical Sxs of this MC
What will be seen on PE
Cataracts
Blurred yellow vision w/ increase sensitivity to glare
Central opacity
Dec red reflex
What is the leading cause of irreversible vision loss in PTs >65y/o
What are the two types and characteristics of each
Age related macular degeneration
Non-neovascular, dry (MC):
Gradual central blurring
Difficult reading fine print/street signs, facial recognition
Rx: antioxidants and Zinc
Neovascular, wet:
Rapid central vision loss
Refer for Tx w/ anti-VEGF
How does Diabetic Retinopathy present
How is it managed
What exam is needed annually
Blurred vision
Field constriction
Scotoma
Observe w/ referral
Dilated funduscopic exam
What are 4 types of eye complaints that require immediate referral?
Cerumen impaction will present w/ ? PE findings
What age related deterioration is overlooked but a contributor to morbidity
Rapid Painful Monocular
Vision loss
Weber to L
Rinne BC>AC on L
Hearing loss
Hearing loss is independently associated w/ ? issues in PTs
What is the MC type of hearing loss
What causes conductive hearing loss in these PTs
Incident dementia Accelerated cognitive decline Poor neurocognitive function Increase falls Gait disturbance
Sensorineural HL- presbycusis
Perfs Impaction Effusions
What are the Aminoglycoside antibiotics associated w/ hearing loss?
What is the criteria for OHOTN
Gentamicin Amikacin Vancomycin Erythromycin Neomycin Streptomycin
SBP dec 20mm
DBP dec 10mm <3min of Sxs
How is cognitive impairment different from normal aging to concerning?
Define Mild Cognitive Impairement
Normal aging- PT remembers later w/ intact learning and subtle deficits in memory function w/out functional impairment
Cognitive function below normal for age/education but severe enough for dementia
MCI is characterized by what 3 parameters
Subjective complaints validated by second person
Evidence of objective cognitive impairment in one of more domain
Intact functional status
If PT presents w/ memory loss and draws all numbers on one side of a clock, ? is Dx
When does the Dx of Dementia begin and how quickly does the risk increase?
Vascular dementia
Starts at 60
Doublex every 5yrs
What are the 5 types of dementia in order of frequency and RFs for each
Alzheimer-
RF: Age FamHx
Lewy Body- Parkinsonism Visual hallucinations Cognitive fluctuant
Vascular-
RF: DM Age Smoking HTN Lipidemia
Frontotemporal- Personality/Social behavior changes Nonfluent speech
Neurodegenerative-
Huntingtons Metabolic abnormalities
What are the key features of Dementia
What is focused on during PE
PTs present w/ memory loss, temper change worse at end of day and disagrees w/ caregiver, what assessment is done
Gradual, stable onset
ADL interference
Inattention on gradient
Non-reversible cognitive decline
Functional assessment w/ ADL/IADLs
Neuro exam
Mini Mental state exam- 3 item recall, clock test
Both norm= r/o dementia
When/what PT would be considered high risk for dementia
How often are Mini Mental State Exams repeated?
What does this test indicate or suggest for Dx
> 80y/o
q6-12mon
Cognitive decline, suggests Dx of MCI, dementia
MOCA test is more influenced by ? and is more ? than MMSE
What general labs are ordered for a Dementia work up
What specific labs would be ordered?
Education
Sensitive, particularly for detecting MCI
CBC Chem-18 (Kidney E+ Glucose Liver)
BETCH CDR
B12 ETOH TFTs Ca HIV
CSF Drug/Tox screen RPR
What other Dx co-exists w/ dementia in half of PTs
Why is identifying this co-existing Dx important
How would this underlying issue be suspected
Depression
Can be cause of cognitive defecits
Must be ID’d/r/o prior to Dx of dementia
Memory complaints OOP to deficits
Define Delirium
What is the classic triad for Alzeimers
Sensory deficit Other psych d/0 Delerium Depression Alcohol abuse Meds- BEERS LIST
Memory impairment
Visuospatial problems
Language impairment
Alzheimer
Early: retain social function, fail complex tasks
Disorientation:
Time Place Person
Languae:
Anomic Fluent Mutism
Lost in familiar places
Behavior changes common
Lewy Body Dementia
2nd MC dementia:
Parkinsonism after/w/ onset
Parkinson dementia is late in dz
Fluctuating cognitive impairment
Visual hallucination- can differ real from fantasy w/out concern
REM sleep d/o and severe sensitivity to antipsychs- suggest LBD
Vascular Dementia
Dx base on radiographic evidence of cerebrovascular dz
Sudden onset after stroke/step wise, not continuous
Patchy deficit, not as severe as Alzheimer
Fronto Temporal Dementia
Younger onset, 50y/o, Mis-Dx as Pysch d/o
Picks Dz:
Behavior/Personality changes w/ intact memory
Hyperorality
Loss of social awareness, spares visuospatical abilites
Develops new artistic talent
Progressive aphasia
Semantic dementia
What meds are used in Dementia Tx for Cognitive Impairement
Cholinesterase inhibitor, ChEI- Galantamine Rivastigmine Donepezil Differ in t1/2, titrate x 8-12wks S/e: GI Syncope Bradycardia Improved MMSE/MOCA 6-12mon= effective
Memantine- NMDA antagonist
Added to ChEl when dementia reaches moderate severity
S/e: HA
How is Vascular dementia Tx
What non-pharmaceutical Tx can be done for behavior problems
Tx RFs for stroke:
Tobacco HLD AFib DM
Permissive HTN- SBP 150+
Consider ChEI (GRD), Memantine
Bright light Music Walk Pets
What meds can be used for Dementia induced behavior problems?
SSRI Mood Antipsych stabilizer ChEIs
Olanzapine/Risperidone-
Anti-psych, best effectiveness
BBW: mortality, CV events, Tardive diskinesia in dementia PTs
Citalopram- SSRI
Carbamazepine/Valproic Acid- mood stabilizer
What Tx methods are not recommended for dementia due to lack of efficacy/potential for harm?
What are the criteria for major depression
Gingko biloba Estrogen NSAID Vit E
Two weeks w/ at least:
Depressed mood and/or Anhedonia
Plus 3-4: SIGECAPS
Sleep Interest Guilt Energy Concentration Appetite Psychomotor SI
What screening tool is used for detecting depression in in older adults?
What are the DDxs?
PHQ-2
Delirium
Cognitive impairment
Chronic medical condition (weak/fatigue)
What meds are used for depression in adults and their s/e
SSRIs: Esc/Citalopram Fluoxetine Paroxetine Sertraline
Citalopram: QT prolongation, Torsades- Max 20mg
Fluoxetine: long t1/2, P-450 inhibitor
SNRI: Des/Venlafaxine Duloxetine
TCA: Amitriptyline Imipramine Doxepin
Rarely used in older adults d/t s/es
Mirtazapine- appetite stimulant, insomnia
Buproprion- smoking cessation
What are the risks of SSRIs as a class
What are the risks of TCAs
Seratonin Syndrome HTN HypoNa Inc bleeding risk w/ anti-coagulants Fall risk
OD
OHOTN
Arrhythmia
Cognitive impairment
When do depressed PTs need to be referred to Psych
What are three meds that are hydrophilic and would bind to proteins and decrease available amount?
What 3 classes of drugs cause 2/3 of hospital admissions
Mania/Psychosis
Failure x 2 meds
Electroconvuslive therapy
RF for SI
TSH Warfarin Phenytoin
Anticoagulant/platelets
Diabetes
What is the two types of Pneumoccoccal vaccine given at 65y/o
When are herpes zoster vaccines given?
What age are cervical screenings stopped
PPSV23 and PCV 13
50y/o
65y/o
When are lung CTs needed for smoking PTs
When is osteoporosis screened for ?
How often is hyperlipidemia screened for
55-80y/o w/ 30ppy or quit <15yrs
F >65y/o, initial
M >70y/o, consider
Initial, q5yrs
Urgency Incontinence Sxs
Causes
Tx
Detrusor over activity- Involuntary loss followed w/ urgency
Stroke
Alzeihmers/Parkinson
BPH w/ overflow
Anticholinergic
Stress urinary incontinence Sxs
Causes
Tx
Loss of urine w/ strain/exertion from sphincter failure
Pelvic floor weakness (surgery/birth)
Prostate surgery Hx
Topical estrogen
Mixed urinary incontinence Sxs
Causes
Involuntary loss of urine w/ urge and w/ exertion/stress
Combo of urge and stress
Overflow incontinence Sxs
Causes
Tx
Weak stream, incomplete emptying
BPH
Impaction/fibroids
Diabetic neuropathy
Pelvic organ prolapse
Alpha adrenergic blockers
PT presents w/ stress urinary incontinence, what test is used to confirm Dx?
What two tests can be ordered for urinary incontinence
Bladder stress test
UUI: bladder competence/detrusor over activity
SUI: urethra function, post-void residual
How do anticholinergics contribute to urinary incontinence?
How do diuretics contribute to urinary incontinence?
How do opioids contribute to urinary incontinence?
Affect bladder wall/sphincter
Inc volume/diuresis
Receptor induced dysfunction
How do A-adrenergic agonists contribute to urinary incontinence?
How do A-adrenergic antagonists contribute to urinary incontinence?
How do CCBs contribute to urinary incontinence?
Urethral sphincter constriction
Urethral sphincter relaxation
Dec smooth muscle contractility
How is stress incontinence Tx
How is Urge incontinence Tx
How is overflow Tx
Kegels/Pessaries
Estrogen
Surgery
Estrogen
Antimuscarinic- Oxybutynin
B-agonists- Mirabegron
Alpha blocker- Doxazosin
5a inhibitors- Finasteride
Cath/Surgery
Define Scoliosis
Define Kyphosis
Define Lordosis
Spine is C or S shaped
Thoracic spine curves out
Lumbar spine curves inward
How does OA present
What will be seen on PE
What would be seen on x-rays
Mechanical pain worse w/ activity, better w/ rest
Joint line tenderness w/ bone enlargements
Narrowing, osteophytes, sclerosis and cysts
What meds are used for OA Tx
Where are fragility Fxs due to osteoporosis likely to occur
What algorithm is used to calculate a PTs 10yr Fx risk
Acetaminophen- initial choice
NSAIDs- acetaminophen failure
Tramadol
Hip Vertebrae Wrist
FRAX
What are the three classifications of osteoporosis
Type 1: post-menopause loss of estrogen
Type 2: >75y/o, loss of Zinc, lack of Ca intake
Secondary: chronic dz or medication induced (GCSS); equal in M-F
What DEXA measurements correlate to normal and osteoporosis
When are DEXA scans recommended
Normal: -1.0 or more
Penia: -1.0 - -2.5
Porosis: -2.5 or less
Severe/established: -2.5 or lower and fragility Fx
65y/o or older
What meds are given for Osteopenia
What DEXA score is osteopenia but is changed to porosis based on criteria
Ca/Vit D 1000/800 w/ weight bearing exercises
Penia w/ FRAX 10yr probability of hip Fx 3% or more or,
10yr probability of other major porosis Fxs 20% or more
What lab tests are ordered for Secondary causes of osteoporosis
Hypogonad- T, Prl
Primary HyperPara- PTH
Secondary HyperPara- 25 Hydroxy Bit D, PTH
Multiple myeloma- eletrophoresis, free light chains
HyerThyroid- TSH
Malabsorption- transglutaminase Ab
Hypercortisolism- urine cortisol
Mastocytosis- tryptase, urine N-methylhistidine
What meds are first line Tx for Osteoporosis
What selective estrogen receptor modulator may be sued
Bisphosphonates-
AIR-onate
Zoledronic acid
Raloxifene
Delirium
Abrupt onset that fluctuates over hrs-wks
Impaired attention, alertness, orientation
Disrupted sleep-wake cycle
Agitated/withdrawn
Dementia
Insidious onset w/ slow decline over mon-yrs
Attention intact early, impaired later in dz
Normal sleep, alertness
What is pathognemonic for delirium
What other key features may be seen
Acute change in baseline mental status over hrs/days
Fluctuating Rambling Alerted LoC Inattention Disorganized thinking
What is the leading precipitating factor to delirium
What are examples of this leading cause
Medications
Sedative hypnotics Opiates Anticholinergics Polypharm Benzos ETOH TCAs CCS H2 receptor antagonists
? may be the first sign of serious underlying dz
What must be carefully r/o
Delirium
Occult infection
Define the Confusion Assessment Method
What are two features not seen in mild/mod dementia
Worsening confusion above baseline cognitive impairment suggests ? Dx
Acute onset, fluctuating and,
Inattention and
Disorganized thought or Altered LoC
Inattention
Altered LoC
Delirium
What are the steps of delirium Tx
What meds are last line choices for Tx
What needs to be avoided
ID/Tx underlying cause
Eradicate contributing factors
Manage Sxs
Risperidone Olanzapine Benzos
Haldol Quetiapine
Restraints
What are the 4 characteristics of Parkinsons
What causes these Sxs
What is the name of the gait they adopt
Bradykinesia
Muscle rigidity- cog wheel
Posture instability- late
Resting tremor- pill rolling
Loss of substantia nigra and depletion of dopamine
Festinating
? is the second MC degenerative neuro d/o after Alzheimer
With an onset between 60-65, if a PT present older than ?, Dx is usually primary or secondary
What is a required feature for Dx
Parkinsons
> 75
Bradykinesia plus 1 Sx
? is the MC cause of Parkinson’s
What presentations are red flags for secondary causes
What is the strongest alerting factor
Idiopathic
Symmetric
Lack of tremor
Atypical features
Lack of response to high dose of dopamine/Levodopa
What are two classes of drugs that can induce Parkinsons
Define Parkinson Plus Syndrome
What are the first and second line meds for depression in Parkinson PTs
Antiemetic/psychotic
Atypical Parkinsons- associated w/ disabling features (autonomic failure, early fall/dementia)
1: SSRI, 2: SNRI
Parkinson PTs may need to have ? meds d/c as Dz progresses
What medication may be added for PTs that develop dystonia/involuntary movements while on carbi/levodopa
Anti-HTN
Pramipexole- dopamine agonist
S/e: drowsy hallucinations risk-taking behavior
? is the DOC for Parkinson PTs >70y/o and <70y/o
Above is the DOC because ? meds work poorly in these age groups?
What enzyme converts Levodopa into Dopamine
> 70:Levodopa
<70: Pramipexole, Ropinirole
Pramipexole
Amantadine
Ropinirole
Anticholinergics
DOPA-decarboxylase