GI: Diarrhea - Ascites Flashcards
PTs may define diarrhea as ?
Frequent, more than 3/day
Loose, watery
Urgency
What is the criteria for persistent diarrhea
What is the limit for chronic diarrhea?
Diarrhea lasting between 2 and
4 wks
+4 wks
What are two important considerations in the work up for diarrhea?
Acute vs Chronic
Non vs Inflammatory
Etiology of acute diarrhea
Are these present?
Severe illness (<7days; Fever, Pain, Bloody diarrhea, +6 BMs/24hr, Dehydration)
Immunocompromised
Elderly +70yrs
What is the next step for treating acute diarrhea if the severe illness, immune compromise of non-elderly criteria are NOT met?
Sx therapy: anti-diarrhea- loperamide, bismuth subsalicylate
What is the next step when treating acute diarrhea and the severe illness, immune compromise of non-elderly criteria are ARE met or illness is present after 7-10 days after Sx therapy?
Stool sample for: Fecal leukocyte Routine stool culture C Diff Ova/parasite testing- if travel, +10day, water outbreak, relationship criteria is met
Acute diarrhea meeting severe illness/immune/elder criteria or or lasting 7-10 days after Sx therapy will have stool samples tested for ova/parasite. Empiric ABX therapy is considered while waiting culture if ?
\+ fecal leukocyte Bloody diarrhea Fever Ab pain Dehydration/ +8 BMs/24hrs Immunocompromised Hospitalization REQ'D
Acute diarrhea lasting less than 2wks is most commonly caused by ?
Acute non-inflamm: virus, non-invasive bacteria
Acute inflamm: invasive or toxing producing bacteria
Characteristics of acute inflammatory diarrhea?
Blood, pus or fever
Invasive/toxin producing bacteria
Stool cultures: E Coli O157:H5 and O157:H7, C Diff and Ova/parasite
What are the Viral causes of noninflammatory diarrhea?
Norovirus* Rotavirus* Astrovirus Adenovirus Sapovirus
What are the Protozoal causes of non-inflammatory diarrhea?
Giardia*
Crytposporidium
Cyclospora
What are the bacterial causes of non-inlfammatory diarrhea?
Preformed enterotoxins= Staph A, Bacillus Cereus, Clostridium Perfringens
Enterotoxin production= E Coli ETEC, V Cholera, Vibrio Vulnificus
What are the viral and protozoal causes of inflammatory diarrhea?
V= cytomegalovirus P= entamoeba histolytica
What are the bacterial causes of inflammatory diarrhea?
Cytotoxin producing- EHEC H5/H7, V parahaemolyticus, C Diff
CYCLASES PY
Mucosal invasion= Shigella, C Jejuni, Salmonella, EIEC, Aeromonas, Plesiomonas, Yersinia entercolitica, Chlamydia, N Gonorrheoae or Listeria Monocytogenes
What are the relevant Hx facts for acute diarrhea?
Bloody vs watery (nonbloody) Recent travel Diet/new places ABX use Sick contacts
What are the essentials of Dx for non-inflammatory diarrhea?
Duration less than 2wks Watery, non bloody Mild, self limited Virus/non invasive bacteria SMALL Bowel Dx eval only if severe/+7 days
What are the common etiologies of non-inflammatory diarrhea?
Viral- Norovirus, Rotavirus
Protozoa- Giardia (water park)
What are the S/Sx of non-inflammatory diarrhea?
Loose water stool 10 bm/day Cramps Bloat N/V Signs of dehydration- dizzy, light headed, OHOTN
What are the essentials of Dx for Acute Inflammatory diarrhea
Less than 2wks
Blood, pus, or fever usually caused by invasive/toxin producing bacteria in
LARGE bowel
What does diagnosis evaluation require for Acute Inflammatory Diarrhea?
Routine stool culture for E Coli O157:H7
Testing is indicated for C Diff and parasite/ova
What are the common etiologies of Acute Inflammatory Diarrhea?
E Coli
Shigella
Salmonella
C Diff- if recent ABX use
What are the Sx of Acute Inflammatory Diarrhea?
Loose bloody stools but lower in vol
Fever and severe LLQ pain
Tenesmus
What are the Signs of Acute Inflammatory Diarrhea that prompt evaluation?
Signs of inflammatory diarrhea: fever, WBC +150K, Blood diarrhea w/ severe ab pain Frail elderly/nursing home PT Immunocompromised Nosocomial, onset in 3 days ABX exposure Systemic illness
What are the evaluation steps for Non/Inflammatory Diarrhea?
Non= Self limited and mild
Labs usually not req’d unless persists +7 days or constant/severe dehydration
Inflammatory= prompt eval for ALL cases
If PT presents with acute diarrhea, what findings/signs prompt a immediate/further evaluation?
Peritoneal findings present with W Diff or STEC
What are the lab tests needed for acute diarrhea?
Fecal leukocytes- will be neg in non-inflammatory PTs
Stool culture- OP, 3 samples needed
C Diff if recent ABX use
Fecal Lactoferrin- marker for intestine inflammation
What are the general treatment strategies for acute diarrhea?
BRAT Avoid high fiber foods, fats, dairy and caffeine Re-hydrate PO liquids Oral rehydration salts
What pharmacotherapy is recommended for acute diarrhea PTs?
What is the down side/consideration for these?
Antidiarrhea
Loperamide
Bismuth subsalicylate
Used to allow PT to continue work/mission, works AGAINST the body’s mechanisms
When are ABX considered to be given to Acute Diarrhea PTs?
Not always indicated
Non-hospital acquired diarrhea w/ mod/severe fever, tenesmus or bloody stool, or presence of fecal lactoferrin
Immunocompromised PTs
Significant dehydration
Emipiric treatment may be considered for what acute diarrhea PT while their stool cultures are growing?
Non-hospital acquired diarrhea w/ mod/severe fever Tenesmus Bloody stool No STEC suspicion Immunocompromised PTs Significant dehydration
What is the pathophysiology of Traveler’s Diarrhea
Most commonly from ETEC in PTs w/ Hx of recent travel that presents w/ abrupt, watery diarrhea, cramping and nausea w/in 10 days of return
How is Traveler’s Diarrhea managed?
ETEC most commonly caused S/Sx
Rehydrate, Cipro, Azithromycin- if pregnant
Diarrhea, Ab cramping, Nausea, Bloating
What ABX are used for empiric treatment for acute diarrhea?
Fluoroquinolones are DOC Ciprofloxacin 500mg BID Ofloxacin 400mg BID Levofloxacin 500mg QD All for 5-7days Others: Trimethoprim-sulfamethoxazole 160/800mg BID Doxycycline 100mg BID
Are ABX recommended for Traveler’s Diarrhea?
Diarrhea onset w/in 10 days of return- ABX can shorten duration by days
Rx can also be given to PTs prior to travel
What meds are given for inflammatory Traveler’s Diarrhea?
PO DOC for empiric treatment: Ciprofloxacin 500mg Ofloxacin 400mg or, Levofloxacin 500mg 1/day for 1-3 days Alternatives= Trimethoprimsulfamethoxazole 160/800mg BID Doxy 100mg BID
What meds are used for Inflammatory Traveler’s Diarrhea non-empirically?
Fluoroquinolones- 3 day course but not useful in SE Asia
Azithromycin 1 g single dose
Rifaximin 200mg TID x 3 days
Fluoroquinolones, Azithromycin and Rifaximin are specific treatments for Inflammatory Traverl’s Diarrhea that are caused by what microbes?
Shigellosis Cholera Extraintestinal Salmonellosis Listeriosis Traveler's D C Diff Giardia Amebiasis
What meds are used for non-inflammatory Traverl’s Diarrhea?
Rifaximin- 200mg BID x 3 days and Azithromycin 1g single dose or 500mg daily x 3 days for EMPIRIC treatment
When are PTs with Traveler’s Diarrhea considered for admission?
Severe dehydration of IV fluids especially if intolerable to PO fluids
Bloody diarrhea
Severe ab pain
Fever +39.5*C or sepsis
+70 y/o or immunocompromisesd w/ worsening diarrhea
S/Sx of hemoytic-uremic syndrome
What PO fluids are recommended for Traveler’s Diarrhea rehydration?
Water Gatorade Tea Flat carbonated beverages Or re-hydration salts if necessary
When considering chronic diarrhea, what exclusions must be ruled out?
Causes of acute Lactose intolerance IBS Previous gastric surgery/ileal resection Parasitic infection Meds Systemic Dz
What labs/tests are done for a chronic diarrhea PT?
Fecal leukocytes and occult blood
Colonoscopy with biopsy
Small bowel imaging with barium, CT or MRE
What does it mean if chronic diarrhea labs/tests come back abnormal?
Inflammatory bowel dz
Cancer
What is the next step if chronic diarrhea labs/tests come back abnormal?
Stool E+, osmolality, weight/24hrs and quantitative fat
ALMOST ALL CASES REFERRED TO GI
What are the next steps/considerations if chronic diarrhea PT has an increased osmotic gap?
Inc fecal fat= malabsorption, pancreatic insufficiency or bacterial overgrowth
Norm fecal fat= lactose intolerance, Sorbitol/Lactulose laxative abuse
What are the next steps/considerations if chronic diarrhea PT has a normal osmotic gap?
Normal stool weight= IBS or factitious diarrhea
Inc weight= secretory stool weight
For diarrhea to be considered “chronic”, it must be present for how long?
What are the common causes that must be immediately ruled out?
Longer than 4wks
Meds
Chronic infections
IBS
What are causes of chronic diarrhea?
Osmotic/secretory diarrhea Inflammation conditions Meds Malabsorption syndromes Motility disorders- IBS Chronic infections Systemic disorders
What are the Hx questions for Chronic Diarrhea?
Continuous / intermittent Relation to meals Nightly occurence? Fasting occurence? Appearance Ab pain/cramping Meds Weight loss Stressors
What are the most common causes of chronic diarrhea and need to be ruled out prior to work up?
Meds
IBS
Lactose intolerance
What findings/Sx are inconsistent with the most common causes of chronic diarrhea and warrant further evaluation?
Nocturnal diarrhea
Weight loss
Anemia
Pos FOBT
What is the first part of the work up for chronic diarrhea?
Exclude most common causes (Med, LI, IBS)
Evaluation directed at most likely etiology based on Sx and Hx
What are the lab tests for Chronic Diarrhea?
CBC Chem 17 LFT Thyroid studies ESR CRP
What stool studies are ordered for chronic diarrhea?
Culture Leukocytes Lactoferrin Occult blood O&P E+
Why is a colonoscopy with biopsy warranted for a chronic diarrhea PT?
What are the “other” tests that can be ordered?
Exclude IBD and neoplasm
24hrs stool collection- total weight/total fat
What are the clues for Osmotic Diarrhea
Stool volume decreases w/ fasting
Increased osmotic gap that resolves with fasting
What are the etiologies for osmotic diarrhea?
*Carbohydrate malabsorption- consider in all Pts w/ chronic posprandial diarrhea, ask about dairy/artificial sweetener intake
Lax abuse
Malabsorption syndrome
How is Osmotic Diarrhea identified?
Elimination trial: Laxative abuse, malabsorption
Diagnosis of carb malabsorption can be established after how long of an elimination trial?
2-3 wks or,
H breath test
What are the most common causes of Osmotic Diarrhea?
Carbohydrate malabsoprtion- lactose, fructose, sorbitol
Laxative abuse
Malabsorption syndromes
Osmotic diarrhea resolve during ___ and are characterized by ?
Resolve during fasting
Characterized by- abnormal distension, bloating, and flatulence from inc colonic gas
What is the definition/criteria for Secretory Diarrhea?
+1L/day
Normal osmotic gap that doesn’t change w/ fasting
Inc intestinal secretion and/or decreased absorption
What are the etiologies of Secretory Diarrhea?
Endocrine Tumors
Bile Salt malabsorption
What are the clues of inflammatory chronic diarrhea?
Fever
Hematochezia
Ab pain
What are the causes of inflammatory diarrhea?
IBDz- Crohn’s, Ulcerative colitis
Microscopic colitis
Malignancy- lymphoma, adenocarcinoma
What types of meds can cause chronic diarrhea?
SSRs NSAIDs PPIs ARBs Metformin Allopurinol
What are the clues for malabsorption from diarrhea?
Weight loss
Fecal fat >10g/24hrs
Abnormal labs
What are the clues of motility diarrhea?
Systemic dz or ab surgery
Systemic= DM, scleroderma, hyperthyroid, IBS
Pain/altered bowel habis w/o evidence of organic dz
What are the clues for chronic diarrhea?
Parasites or AIDS
Parasites= Giardia, E Histolyitca, Cyclospora or intestinal nematodes
Systemic= Thyroid Dz, Diabetes
Define Factitious Diarrhea
Osmotic diarrhea subset from magnesium (laxatives and anti-acids)
What are the initial diagnostic tests for chronic diarrhea in order of sequence?
Routine lab tests
Routine stool studies
Endoscopic exam
What are the lab tests ordered for chronic diarrhea?
CBC Serum E+ Liver chemistry Ca, PO4 Albumin TSH Vit A and D levels INR, ESR, CRP
Most PTs with chronic diarrhea and ALL pts with signs of malabsorption receive what lab test?
Celiac Dz- IgA tissue transglutaminase
Anemia can occur in which malabsorption syndromes?
Folate
Fe deficiency
Vit B12
Inflammatory conditions
Hypoalbuminemia is present in what conditions?
Malabsorption
Protein-loss enteropathies
Inflammatory dz
Hyponatremia and nonanion gap metabilic acidosis occur in what type of diarrheas?
Secretory
Inc ESR or CRP suggests what GI issue?
Inflammatory bowel disease
What are stool samples examined for during a chronic diarrhea PTs?
Ova/parasites E+ Sudan stain for fat Occult blood Leukocytes/lactoferrin
Cryptosporidia, Giardia, E Histolytica and Cyclospora may be diagnosed how?
Stool Ag or,
Microscopy
Pos fecal fat stain indicates what?
Presence of fecal leukocytes or lactoferrin suggest ?
Malabsorption disorder
Inflammatory bowel dz
Endoscopic exams for chornic diarrhea are perfromed to exclude ?
Inflammatory Dz- Crohns, Ulc. Colitis
Microscopic colitis
Colonic neoplasia
When are upper endoscopy performed on PTs with chronic diarrhea?
Abnormal labs/pos fecal occult suggest small intestinal malabsorptive disorder (Celiac, Whipple)
AIDS to document Crypto/Microsporidia or M Aviumintracellulare infection
What further studies can be performed when chronic diarrhea causes are not apparent after the first three standard tests?
24hr stool collection quantification of weight/fat
X-ray/CT
Serological Screening for Neuroendocrine tumors
Breath tests
Stool samples with weights less than 200-300g/24hrs excludes ? and suggests ?
Excludes diarrhea
Suggests functional disorder- IBS
Stool samples with weights more than 1000-1500g/24hrs suggests ?
Suggests significant secretory process- neuroendocrine tumor
Fecal fat exceeding 10g/24h suggests?
Confirms malabsorptive order
Fecal elastase less than 100mcg/g may be caused by ?
Pancreatic insufficiency
Abdominal x-ray on a PT with chronic diarrhea showing calcification confirms what Dx?
Chronic pancreatitis
What antidiarrheal agents can be used in PTs with chronic diarrhea?
Loperamide* Bismuth subsalicylate* Diphenoxylate w/ atropine Codein/Deodorized opium tincture Clonidine Bile salt binders
What are the signs of an upper GI bleed?
Hematemesis- bright red blood or coffee grounds
Melena in most cases
Hematochezia in massive upper GI bleeds
Possible pain- epigastric, abdominal
For upper GI bleeds, how is the amount of blood loss determined?
Volume status
HcT is poor early indicator
What are the four types of GI bleeds?
Upper Lower Obscure
Occult
What are the essentials of Dx for acute upper GI bleeds?
Hematemesis
Varying hypovolemia
Possible melena
Hematochezia in massive bleed
What are the etiologies of acute upper GI bleeds?
PUD
Portal HTN= esophageal varices
Mallory Weiss tear- strong association with alcohol abuse
Vascular abnormals
Neoplasm
Other- erosive gastritis/esophagitis/Booerhave Synd
What is the most common presentation of upper GI bleeds?
Hematemesis or melena
Melena from 50-100mL of loss
Hematachezia reqs 1L
Severe upper GI bleeds present with hematochezia in 10% of cases
Upper GI bleeding is self limited in __% of PTs while the rest of PTs require?
80%
Rest require urgent medical therapy and endoscopic evaluation
What type of PT have a low risk of recurrent bleeding?
PTs w/ bleeding more than 48hrs prior to presentation
Initial eval/treatment for upper GI bleeds?
Stabilize- SBP below 100mm or HR above 100bpm= high risk
If upper GI bleeds do not need blood transfusion, what next step is considered?
What do you not do?
NG tube- useful in assessment and triage
Aspiration of red blood/coffee grounds confimrs upper GI source
NO GASTRIC LAVAGE
What meds are given/used for upper GI bleeds?
Erythromycin 250mg IV 30min prior to gastric emptying
Did not add any cards
Below blood replacement of Upper GI BLeed
Clinical predictors of increased risk of rebleeding and death include what factors?
\+60y/o Comorbid illnesses SBP below 100mm HR +100bpm Bright red blood NG aspiration or rectal exam
What are the characteristics of the High/Low risk PTs after upper GI triage?
High: Admit to ICU, endoscopy performed in 2-24hrs
Low: admitted to step down unit/ward
Non-emergent endoscopy within 12-24hrs
PUD ulcers account for __% of major upper GI bleeds with a _% mortality rate
Portal HTN accounts for _%
Mallory Weiss tears ?%
40% at 5%
10-20%
5-10%
What are the most common cause of vascular anomalies of GI bleeds?
Angioectasias- distorted vessesl from chronic/intermittent obstruction of submuccosal veins most commonly in R colon
What are the causes of gastric mucosal erosions that can lead to erosive gastritis and upper GI bleeds?
NSAIDs
Alcohol
Severe medical/surgical illness
What are the steps of care if PT presents as unstable during an upper GI bleed?
Start IV
CBC, PT/INR, CMP, Type/Screen
Fluid/blood replacement- isotonic fluid, 2-4 units
NG tube
EGDs are warranted for which upper GI bleeds?
ALL with active bleeds within 24hrs of presentation
What are the three benefits of an ednoscopy in an upper GI bleed?
ID source
Determine re-bleed risk
Intervene- cautery, vasoconstrict, band/clip
Homeostasis
What is the follow on pharmacotherapeutic care fo upper GI bleeds?
PPI- reduce rebleed risk factors
Octreotide- red BP and risk of re-bleed risk
What is defined as mild lower GI bleeding?
Bright red blood dripping into bowl or is mixed with brown stool
Eval’d on outpatient setting
What is the etiology of lower GI bleeds?
IBDz- especially ulcerative colitis
What are the other S/Sx of lower GI bleeds?
Ab pain
Tenesmus
Bleeding from occult to recurrent hematochezia
Brown stools mixed/streaked with blood predict the source being where?
Rectosignmoid or anus
Large volumes of bright red blood suggest a bleeding source where?
What if blood is maroon color?
Colonic source
Maroon- lesion in R colon or small intestine
Painless large volume lower GI bleeds are indicative of ?
Diverticuli bleed
What type of lower GI bleed is a colonoscopy the preferred initial study?
Acute large volume bleeds requiring hospitalization
Treatment for all lower GI bleeds includes?
Triage/Stabilization
Blood replacement
What are the purposes and perks of a therapeutic colonoscopy?
High risk lesions treated endoscopically w/ epinephrine injection/cautery/metal clips or TC-325 powder
What is the major common side effect/reaction to a lower GI bleed endoscopy?
Ischemic colitis- 5%
Re-bleed- 25%
When is surgical treatment indicated for PTs with lower GI bleeds?
What usually causes this type of bleeds?
Ongoing bleeds requiring more than 6 units of blood in 24hrs or,
10 total and endoscopic treatment has failed
Caused by bleeding diverticulum or angioectasia
Surgical treatment may be a consideration for diverticulum PTs meeting what criteria?
Two or more hospitalizations for diverticular hemorrhage
Define Anorectal disease
Hemorrhoids, fissures; usually cause small amount of red blood on TP or streaking in bowl
Hemorrhoids in 10% of admitted PT w/ lower bleeds
Rectal ulcers usually present in what PT population?
8% of elderly or debilitated PTs w/ constipation
What PT population is ischemic colitis usually seen in?
Older PTs with atherosclerotic disease
Younger= vasculitis, coagulation disorder, estrogen therapy, long distance running
What S/Sx will a PT with ischemic colitis present with?
Hematochezia or bloody diarrhea w/ mild cramps where bleeding is mild/self-limited
What does radiation induced proctitis cause after a time delay?
Anorectal bleeding revealing telangiectasias
What are all of the etiologies of lower GI bleeds?
Diverticulosis Angioectasias- common +70y/o Neoplasms IBDz Anorectal Dz- hemorrhoid, fissure, ulcer Ischemic/infection colitis Other- telangiectasias
Bleeding from the small intestines can be ? or ? but manifest as ?
Overt or occult
Melena, maroon stools or bright red blood per rectum
What is the most common cause of small intestinal bleeds in PTs younger than 40?
Neoplasms- stromal tumor, lymphomas, adenocarcinoma or carcinoids
Crohns Dz
Celiac Dz
Meckel Diverticulum
Also occur in PTs +40 but angioectasias and NSAID induced ulcers are more common
Define occult bleed
Bleeding not apparent to PT, can be less than 100ml/day and not cause any changes in stool
How are occult bleeds found in adults?
Pos FOBT
FIT- only detects lower bleeds
Fe deficiency anemai
What are the most common causes of occult bleeds with Fe deficiency?
Neoplasm Vascular abnormality Acid-peptide lesion Infection Meds IBDz
Majority of acute lower GI bleeds arise from what part of the GI system?
Colon
Lower risk of serious blood loss than upper GI bleed
Most likely consideration for PTs less than 50y/o and have lower GI bleeds?
Anorectal Dz
IBDz
Infectious colitis
Most likely considerations for PTs over 50y/o and have lower GI bleed?
Diverticulosis
Malignancy
Angioectasias
Ischemic Colitis
Bright red blood = ? source
Maroon color?
Black?
Left colon- hemorrhoids, fissures, diverticulitis, IBD, colitis
Sm intestine or R colon
Upper GI
Painful defecation/rectal pain means what issues?
External hemorrhoids
Anal fissure
Abdominal pain/cramps means what types of issues?
IBD
Colitis
Painless bleeding is caused by ?
Internal hemorrhoids
Diverticular bleeds
Small volumes of blood loss indicate what issues?
IBD- bloody diarrhea
Hemorrhoids
What labs are drawn for acute lower GI bleed?
CBC
CMP
Anemia is ominous sign, particularly for suspected neoplasm
What is the diagnostics testing methods for acute lower GI bleeds?
First exclude upper GI source
Anoscopy Sigmoidscopy Colonoscopy Technetium scan Angiography Capsule endoscopy
What are the treatment methods for acute lower GI bleeds with large volumes of blood loss?
Therapeutic colonoscopy- vasoconstrictive band, cautery and clips/bands
Intra-arterial embolization
Surgery- +6 units in 24hrs or ten total
Occult GI bleeds must have what lab drawn to check for what?
CBC for anemia
PTs w/out + FOBT and no anemia= ?
PTs with +FOBT and anemia= ?
Colonoscopy
Upper endoscopy and colonoscopy
Who normally has no or some peritoneal fluid?
Men- o
Women- 20mL depending on cycle
What are the two broad categories of ascites?
Associated w/ normal peritoneum
Due to Dz peritoneum
What is the most common cause of ascites?
Portal HTN 2* to CLDz (80% of PTs with ascites)
What is the most common cause of nonportal HTN ascites?
Infections- TB
Intrabdominal malignancy
Inflammatory disorder
Ductal disruption- chylous, pancreatic, biliary
What are the S/Sx of clinical findings for ascites?
Inc girth
Pain may be present depending on cause
What questions need to be asked to ascites PTs?
Liver dz ETOH consumption Transfusions Tattoos Injection drugs Hx of viral hepatitis/jaundice Born in hepatitis endemic area
Fever in a PT with ascites indicates what issue?
Infected peritoneal fluid (bacterial)
PTs with CLDz and ascites are at greatest risk for developing spontaneous bacterial peritonitis
What type of ascites need to be considered if PT is an immigrant, immunocompromised, or malnourished alcoholics?
TB peritonitis
Define Budd-Chiari Syndrome and when would it be found?
Thrombosis of hepatic vein
During ascites work up/PE
What are the lab tests for ascites?
Abdominal paracentesis
Routine- albumin/total protein
What imaging methods are performed for ascites PTs?
Abdominal US
CT/US can distinguish between causes of portal / nonportal HTN ascites
When are laparoscopy procedures in ascites PTs?
PTs with nonportal HTN ascites (low SAAG)
Mixed ascites
What are the etiologies of ascites?
Spontaneous bacterial peritonitis
Malignant ascites
Familial Mediterranean Fever
Stopped at
Etiology of Acites