GI: Diarrhea - Ascites Flashcards
PTs may define diarrhea as ?
Frequent, more than 3/day
Loose, watery
Urgency
What is the criteria for persistent diarrhea
What is the limit for chronic diarrhea?
Diarrhea lasting between 2 and
4 wks
+4 wks
What are two important considerations in the work up for diarrhea?
Acute vs Chronic
Non vs Inflammatory
Etiology of acute diarrhea
Are these present?
Severe illness (<7days; Fever, Pain, Bloody diarrhea, +6 BMs/24hr, Dehydration)
Immunocompromised
Elderly +70yrs
What is the next step for treating acute diarrhea if the severe illness, immune compromise of non-elderly criteria are NOT met?
Sx therapy: anti-diarrhea- loperamide, bismuth subsalicylate
What is the next step when treating acute diarrhea and the severe illness, immune compromise of non-elderly criteria are ARE met or illness is present after 7-10 days after Sx therapy?
Stool sample for: Fecal leukocyte Routine stool culture C Diff Ova/parasite testing- if travel, +10day, water outbreak, relationship criteria is met
Acute diarrhea meeting severe illness/immune/elder criteria or or lasting 7-10 days after Sx therapy will have stool samples tested for ova/parasite. Empiric ABX therapy is considered while waiting culture if ?
\+ fecal leukocyte Bloody diarrhea Fever Ab pain Dehydration/ +8 BMs/24hrs Immunocompromised Hospitalization REQ'D
Acute diarrhea lasting less than 2wks is most commonly caused by ?
Acute non-inflamm: virus, non-invasive bacteria
Acute inflamm: invasive or toxing producing bacteria
Characteristics of acute inflammatory diarrhea?
Blood, pus or fever
Invasive/toxin producing bacteria
Stool cultures: E Coli O157:H5 and O157:H7, C Diff and Ova/parasite
What are the Viral causes of noninflammatory diarrhea?
Norovirus* Rotavirus* Astrovirus Adenovirus Sapovirus
What are the Protozoal causes of non-inflammatory diarrhea?
Giardia*
Crytposporidium
Cyclospora
What are the bacterial causes of non-inlfammatory diarrhea?
Preformed enterotoxins= Staph A, Bacillus Cereus, Clostridium Perfringens
Enterotoxin production= E Coli ETEC, V Cholera, Vibrio Vulnificus
What are the viral and protozoal causes of inflammatory diarrhea?
V= cytomegalovirus P= entamoeba histolytica
What are the bacterial causes of inflammatory diarrhea?
Cytotoxin producing- EHEC H5/H7, V parahaemolyticus, C Diff
CYCLASES PY
Mucosal invasion= Shigella, C Jejuni, Salmonella, EIEC, Aeromonas, Plesiomonas, Yersinia entercolitica, Chlamydia, N Gonorrheoae or Listeria Monocytogenes
What are the relevant Hx facts for acute diarrhea?
Bloody vs watery (nonbloody) Recent travel Diet/new places ABX use Sick contacts
What are the essentials of Dx for non-inflammatory diarrhea?
Duration less than 2wks Watery, non bloody Mild, self limited Virus/non invasive bacteria SMALL Bowel Dx eval only if severe/+7 days
What are the common etiologies of non-inflammatory diarrhea?
Viral- Norovirus, Rotavirus
Protozoa- Giardia (water park)
What are the S/Sx of non-inflammatory diarrhea?
Loose water stool 10 bm/day Cramps Bloat N/V Signs of dehydration- dizzy, light headed, OHOTN
What are the essentials of Dx for Acute Inflammatory diarrhea
Less than 2wks
Blood, pus, or fever usually caused by invasive/toxin producing bacteria in
LARGE bowel
What does diagnosis evaluation require for Acute Inflammatory Diarrhea?
Routine stool culture for E Coli O157:H7
Testing is indicated for C Diff and parasite/ova
What are the common etiologies of Acute Inflammatory Diarrhea?
E Coli
Shigella
Salmonella
C Diff- if recent ABX use
What are the Sx of Acute Inflammatory Diarrhea?
Loose bloody stools but lower in vol
Fever and severe LLQ pain
Tenesmus
What are the Signs of Acute Inflammatory Diarrhea that prompt evaluation?
Signs of inflammatory diarrhea: fever, WBC +150K, Blood diarrhea w/ severe ab pain Frail elderly/nursing home PT Immunocompromised Nosocomial, onset in 3 days ABX exposure Systemic illness
What are the evaluation steps for Non/Inflammatory Diarrhea?
Non= Self limited and mild
Labs usually not req’d unless persists +7 days or constant/severe dehydration
Inflammatory= prompt eval for ALL cases