toxoplasmosis_flashcards
What is the management for symptomatic babies with toxoplasmosis?
Refer to paediatric infectious diseases, Pyrimethamine + Sulfadiazine + Folinic acid for 1 year, monitor LFTs and FBCs every 4-6 weeks, add glucocorticoids (prednisolone) if CSF protein >1g or active chorioretinitis threatens vision.
What is the treatment regimen for symptomatic toxoplasmosis in the newborn?
Pyrimethamine + Sulfadiazine + Folinic acid for 1 year.
How often should LFTs and FBCs be monitored in symptomatic toxoplasmosis?
Every 4-6 weeks.
When should glucocorticoids be added to the treatment of symptomatic toxoplasmosis?
If CSF protein >1g or active chorioretinitis threatens vision.
What is the management for asymptomatic babies with positive serology for toxoplasmosis?
No definitive guidelines, discuss individual cases with infection and virology specialists, ongoing ophthalmology and audiology assessment recommended for delayed presentation.
