Neonatal_Hypotonia_Flashcards

Question 1

What are some causes of neonatal hypotonia?

Answer 1

Neonatal sepsis, Werdnig-Hoffman disease (spinal muscular atrophy type 1), hypothyroidism, Prader-Willi.

Question 2

What are some maternal causes of neonatal hypotonia?

Answer 2

Maternal drugs (e.g., benzodiazepines), maternal myasthenia gravis.

Question 3

summarise neonatal hypotonia

Answer 3

Neonatal hypotonia

Causes of neonatal hypotonia include:
neonatal sepsis
Werdnig-Hoffman disease (spinal muscular atrophy type 1)
hypothyroidism
Prader-Willi

Maternal causes
maternal drugs e.g. benzodiazepines
maternal myasthenia gravis

Question 4

You are working on the paediatric ward and are called to see a child who the nurses have noticed is persistently ‘floppy’. You assess the child and find no acute cause for concern and wonder whether there might be an underlying issue.

Which of the following is most likely to be the underlying cause of neonatal hypotonia in this case?

Pierre-Robin syndrome
Becker Muscular Dystrophy
Duchenne Muscular Dystrophy
Congenital Talipes Equinovarus
Prader-Willi syndrome

Answer 4

Neonatal hypotonia: associated with Prader-Willi
Important for meLess important
Hypotonia is associated with Prader-Willi, it is also associated with neonatal sepsis, spinal muscular atrophy and hypothyroidism.