Herpes Simplex Virus_flashcards
Does maternal genital herpes cause pregnancy-related complications or abnormalities to the baby?
No, it is not known to cause pregnancy-related complications or abnormalities to the baby.
What is the main risk to neonates from maternal genital herpes?
Transmission of HSV during childbirth, increasing the risk of neonatal herpes simplex infection, which carries high mortality and morbidity.
What is the prophylactic treatment if primary genital herpes is identified before 28 weeks gestation?
Prophylactic regular aciclovir from 36 weeks gestation onwards.
Is vaginal delivery possible with primary genital herpes before 28 weeks gestation?
Yes, if the woman is asymptomatic and it is more than 6 weeks after the initial infection.
What is recommended if the mother is symptomatic with primary genital herpes before 28 weeks gestation?
Caesarean section.
What is the prophylactic treatment if primary genital herpes is identified after 28 weeks gestation?
Aciclovir during the initial infection, followed by regular prophylactic aciclovir.
What delivery method is recommended if primary genital herpes is identified after 28 weeks gestation?
Caesarean section in all cases.
What is the risk of neonatal infection if the mother has recurrent herpes infection before pregnancy?
Low risk due to antibody transfer across the placenta.
What prophylactic treatment is considered for recurrent herpes infection from 36 weeks gestation?
Regular prophylactic aciclovir to reduce the risk of symptoms.
What prophylactic treatment can be given to the baby during the at-risk period?
Aciclovir or valaciclovir.
What is the management for suspected symptomatic neonatal infection?
Blood, swab and CSF PCR, IV aciclovir (do not treat with oral or topical aciclovir).
What is the treatment if infant treatment is required for neonatal herpes?
Aciclovir.
