flashcards_kawasaki_disease
What is the initial treatment for Kawasaki Disease?
IVIG infusion (single dose, may be repeated 36 hours after completion of the first dose).
What is the role of high-dose aspirin in Kawasaki Disease management?
High-dose aspirin is given to reduce thrombosis risk for 24-72hrs after the fever, then low-dose aspirin is given for 8 weeks.
What are the 2nd line treatment options for Kawasaki Disease resistant to IVIG?
Corticosteroids and infliximab.
What are the 3rd line treatment options for Kawasaki Disease?
Cyclosporin, anakinra, or plasma exchange.
What is the first line risk assessment tool for coronary artery aneurysms in Kawasaki Disease?
Echocardiogram.
What is the management for low-risk coronary artery aneurysms in Kawasaki Disease?
No further medications after 8 weeks of aspirin.
What is the management for moderate-risk coronary artery aneurysms in Kawasaki Disease?
Low dose aspirin until aneurysm regression is demonstrated, with ECG and echo follow up annually.
What is the management for high-risk coronary artery aneurysms in Kawasaki Disease?
Low dose aspirin long term, with ECG and echo follow up twice a year, long term warfarin (INR target: 2-3), and may need clopidogrel.
What additional treatments may be needed for high-risk coronary artery aneurysms in Kawasaki Disease?
Long term warfarin (INR target: 2-3) and may need clopidogrel.
