haemolytic_disease_newborn_flashcards
What is the prevention strategy for Haemolytic Disease of the New-born?
Anti-D immunoglobulin.
How can Anti-D immunoglobulin be administered for prevention?
As a 1500IU single dose at 28 weeks and delivery, or as two doses of 500IU at 28 and 34 weeks, and delivery.
When should further doses of Anti-D immunoglobulin be given?
In any sensitizing events.
What is the resuscitation approach for a baby with Haemolytic Disease of the New-born?
A to E approach, particularly if preterm, anaemic, or hydropic.
When is phototherapy used for a baby with Haemolytic Disease of the New-born?
If there is significant jaundice (test with transcutaneous bilirubin).
When is exchange transfusion indicated for a baby with Haemolytic Disease of the New-born?
If bilirubin is rapidly rising (>8-10 μmol/l/hr) despite adequate phototherapy, severe hyperbilirubinaemia insufficiently responsive to phototherapy and supportive care, or significant anaemia (Hb <100 g/l).
When is IVIG used for a baby with Haemolytic Disease of the New-born?
Only for immune haemolysis if bilirubin continues to rise by > 8.5mmol/L/hour.
What follow-up is required for a baby with Haemolytic Disease of the New-born?
Check for late anaemia at 4-6 weeks (consider folate supplementation) and hearing screen.
What should parents be counselled on regarding Haemolytic Disease of the New-born?
Recurrence of HDN in subsequent pregnancies.
