Chronic Lung Disease of Prematurity (Bronchopulmonary Dysplasia)_flashcards
What is Chronic Lung Disease of Prematurity (Bronchopulmonary Dysplasia)?
A complication of preterm birth, defined as an oxygen requirement in preterm infants at 36 weeks corrected gestational age, associated with classical CXR findings and previous mechanical ventilation.
What is the prophylactic treatment for Chronic Lung Disease of Prematurity?
Corticosteroids for women in suspected, diagnosed or established preterm labour <34 weeks (consider if 34-36 weeks).
What is the recommended respiratory support for Chronic Lung Disease of Prematurity?
High flow oxygen, CPAP, and invasive ventilation with surfactant administration.
What is the caution with high flow oxygen in Chronic Lung Disease of Prematurity?
Care is taken not to over-oxygenate the infant with supplementary oxygen.
What is preferred over intubation and ventilation for Chronic Lung Disease of Prematurity?
CPAP.
What is given during invasive ventilation for Chronic Lung Disease of Prematurity?
Surfactant.
What other management options are there for Chronic Lung Disease of Prematurity?
Caffeine citrate, formal sleep studies, long-term oxygen, and palivizumab.
What is the role of caffeine citrate in Chronic Lung Disease of Prematurity?
Stimulates the respiratory effort.
What is the role of formal sleep studies in Chronic Lung Disease of Prematurity?
These assess the child’s oxygen saturations during sleep, which guides management at home.
How is long-term oxygen managed in Chronic Lung Disease of Prematurity?
Long-term oxygen can be given at home, and children are followed up to wean the oxygen level over the first year of life.
What is the role of palivizumab in Chronic Lung Disease of Prematurity?
Given on a monthly basis to reduce the risk and severity of bronchiolitis.
