flashcards_glomerulonephritis

Question 1

What is the most common cause of glomerulonephritis in children?

Answer 1

Minimal change disease.

Question 2

What are the management steps for nephrotic syndrome with minimal change disease?

Answer 2

Steroids (prednisolone).

Question 3

What are the management steps for nephrotic syndrome with membranous nephropathy?

Answer 3

Low salt and low protein diet, ACE inhibitor or ARB if hypertension and/or proteinuria, statin for hypercholesterolaemia, furosemide if oedema, poor response to steroids/immunosuppression but considered in high risk of progression.

Question 4

What are the management steps for nephrotic syndrome with focal segmental glomerulosclerosis (primary)?

Answer 4

Low salt and low protein diet, ACE inhibitor or ARB if hypertension and/or proteinuria, statin for hypercholesterolaemia, steroids if symptomatic or significant proteinuria, consider adding alternative immunosuppressants if ineffective (e.g., ciclosporin).

Question 5

What are the management steps for nephritic syndrome with IgA nephropathy?

Answer 5

ACE inhibitor or ARB if hypertension and/or proteinuria, consider steroids (and other immunosuppressants) if persistent proteinuria.

Question 6

What are the management steps for nephritic syndrome with post-streptococcal glomerulonephritis?

Answer 6

Low salt and low protein diet, ACE inhibitor or ARB if hypertension and/or proteinuria, furosemide if oedema, consider phenoxymethylpenicillin to prevent spread.

Question 7

What are the management steps for rapidly progressive glomerulonephritis with anti-GBM glomerulonephritis?

Answer 7

Oral prednisolone (plus additional immunosuppressants), plasma exchange.

Question 8

What are the management steps for rapidly progressive glomerulonephritis with ANCA vasculitis?

Answer 8

Oral prednisolone (plus additional immunosuppressants).