flashcards_wilsons_disease

Question 1

What scores are used to assess the severity of Wilson’s Disease?

Answer 1

Nazar score or Kings Wilson score.

Question 2

What is the role of zinc in managing Wilson’s Disease?

Answer 2

Zinc blocks intestinal copper resorption.

Question 3

What are the oral chelation therapies used for Wilson’s Disease?

Answer 3

Penicillamine or trientine.

Question 4

What is the function of trientine in managing Wilson’s Disease?

Answer 4

Trientine increases urinary copper excretion.

Question 5

Why is pyridoxine (vitamin B6) given to Wilson’s Disease patients?

Answer 5

To prevent peripheral neuropathy.

Question 6

What dietary restrictions are recommended for Wilson’s Disease patients?

Answer 6

Reduce liver and shellfish intake.

Question 7

How long may neurological improvement take in Wilson’s Disease?

Answer 7

Up to 12 months.

Question 8

When is liver transplantation considered for Wilson’s Disease patients?

Answer 8

In children with end-stage liver disease.